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Detection of toxigenic Clostridium difficile in diarrheal stools by rapid real-time polymerase chain reaction


, : Detection of toxigenic Clostridium difficile in diarrheal stools by rapid real-time polymerase chain reaction. Diagnostic Microbiology and Infectious Disease 67(3): 304-307

The Cepheid Xpert polymerase chain reaction assay (Sunnyvale, CA) had a sensitivity of 100%, specificity of 96.7%, and positive and negative predictive values of 90.5% and 100%, respectively, compared with toxigenic culture for the laboratory diagnosis of Clostridium difficile in diarrheal stool samples. This test appears to be a significant improvement to poorly performing enzyme immunoassays.

US$19.90

PMID: 20542211

DOI: 10.1016/j.diagmicrobio.2010.02.019


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