geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Diagnostic accuracy of ultrasound features in thyroid microcarcinomas


, : Diagnostic accuracy of ultrasound features in thyroid microcarcinomas. Endocrine Journal 55(5): 931-938

To establish the usefulness of specific ultrasound (US) features as indications for ultrasound-guided fine needle aspiration biopsy (FNAB) in incidentally found infracentimetric thyroid nodules. The ultrasonographic features and cytology of FNAB samples of 96 histopathologically-proven papillary microcarcinomas (less than 1 cm in long diameter) and 75 less than 1 cm sized benign nodules were analyzed and compared. The risk of malignancy indicated by each US feature was calculated by logistic regression analysis. Among the US features examined, internal content, shape, margin, echogenicity, and calcifications showed statistically significant differences between benign and malignant infracentimetric nodules. Crude odds ratios (OR) and 95% confidence intervals (CI) for risk of malignancy were, for solid content, OR = 39.3 (95% CI = 3.3-4.64); for taller than wide shape, OR = 14.2 (95% CI = 1.43-14.1); for hypoechogenicity, OR = 3.57 (95% CI = 1.31-9.86); for marked hypoechogenicity, OR = 31.33 (95% CI = 6.63-14.8); and for coarse macrocalcifications, OR = 3.43 (95% CI = 1.04-11.3). Infracentimetric nodules that are solid, taller than wide, hypoechogenic or markedly hypoechogenic, and have coarse microcalcifications and macrocalcifications have a high risk of malignancy, indicating further assessment.

US$29.90

PMID: 18612179


Other references

Kozbor D.; Steinitz M.; Klein G.; Koskimies S.; Makela O., 1979: Establishment of anti tri nitro phenol antibody producing human lymphoid lines by pre selection for hapten binding followed by epstein barr virus transformation. Human lymphoblastoid cell lines that produce specific antibody against the hapten trinitrophenyl (TNP) were established by selecting TNP-binding human B [bone marrow-derived] lymphocytes by TNP-rosetting and Ficoll-Isopaque separation, followed by...

Yang, J.; Park, O-Jin.; Kim, J.; Baik, J.Eun.; Yun, C-Heui.; Han, S.Hyun., 2016: Lipoteichoic Acid of Enterococcus faecalis Inhibits the Differentiation of Macrophages into Osteoclasts. Enterococcus faecalis is associated with persistent endodontic infection and refractory apical periodontitis. Recently, we have shown that heat-killed E. faecalis attenuates osteoclast differentiation. Because lipoteichoic acid (LTA) is a major vi...

Olatunji, J.O., 1990: Evaluation of Ekiti-Akoko Agricultural Development Project in Ondo state of Nigeria. The twin problems of food and population in Nigeria are examined, together with the roles that Nigerian administrators (past and present) have been playing to ameliorate or compound these problems. As one of its solutions to frequent clashes betwe...

Kotula, L.; Xu, J.; Ziemnicka Kotula, D.; Merz, G.S., 2000: Human spectrin Scr homology 3 domain binding protein 1 is a marker of macropinocytic vesicles and a potential regulator of macropinocytosis. Molecular Biology of the Cell 11(Supplement): 213a, Dec

Rensch, B., 1943: Die palaontologischen Evolutionsregeln in zooogischer Betrachtung. Biol: 1-55

Xiaodong Pan; Fenqin Chen; Tianxing Wu; Honggang Tang; Zhanyu Zhao, 2009: The acid, bile tolerance and antimicrobial property of Lactobacillus acidophilus NIT. Food Control 20(6): 0-602

Wire, R., 1978: When the difficult coronary patient is your husband. Journal of Nursing Care 11(7): 16-17

Pethiya, B.P., 1999: Comparative profitability of agriculture, agroforestry and farm forestry in Maharashtra State, India. While the Social Forestry Project of Maharashtra State (western India) has given due emphasis to farm-forestry programmes, few studies have been undertaken on the socioeconomic implications of adoption of the farm forestry projects. A survey was m...

Inglis R.J., 1976: Chromatin structure and the role of histone phosphorylation in the cell cycle. Heredity 37(1): 148

Lombroso, P.J.; Murdoch, G.; Lerner, M., 1991: Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. A cDNA clone encoding a neural-specific putative protein-tyrosine-phosphatase (protein-tyrosine-phosphate phosphohydrolase, EC 3.1.3.48) has been isolated from a rat striatal cDNA library. The deduced amino acid sequence predicts a protein of appr...