+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Dietary protein and blood pressure: a systematic review

, : Dietary protein and blood pressure: a systematic review. Plos One 5(8): E12102-E12102

Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation to human BP. We performed a MEDLINE search and a manual search to identify English language studies on the association between protein and blood pressure, published before June 2010. A total of 46 papers met the inclusion criteria. Most observational studies showed no association or an inverse association between total dietary protein and BP or incident hypertension. Results of biomarker studies and randomized controlled trials indicated a beneficial effect of protein on BP. This beneficial effect may be mainly driven by plant protein, according to results in observational studies. Data on protein from specific sources (e.g. from fish, dairy, grain, soy, and nut) were scarce. There was some evidence that BP in people with elevated BP and/or older age could be more sensitive to dietary protein. In conclusion, evidence suggests a small beneficial effect of protein on BP, especially for plant protein. A blood pressure lowering effect of protein may have important public health implications. However, this warrants further investigation in randomized controlled trials. Furthermore, more data are needed on protein from specific sources in relation to BP, and on the protein-BP relation in population subgroups.


PMID: 20711407

DOI: 10.1371/journal.pone.0012102

Other references

Bohacova, L.; Uhlirova ; H. ; Lomsky, B., 2004: Forest condition monitoring in the Czech Republic. Annual report ICP forests - data 2003. Faced with the growing concern about forest conditions in Europe, the International Co-operative Programme on Assessment and Monitoring of Air Pollution Effects on Forests (ICP Forests) was established by the UN/ECE under the Convention on Long-ra...

Phillips, T.; Rees, S.; Augood, S.; Waldvogel, H.; Faull, R.; Svendsen, C.; Emson, P., 2000: Localization of metabotropic glutamate receptor type 2 in the human brain. Metabotropic glutamate receptors are a heterogeneous family of G-protein-coupled receptors that are linked to multiple second messenger systems to regulate neuronal excitability and synaptic transmission. To elucidate the physiological role of the...

Pomes, R.; Garcia, A.E., 1998: Nanosecond structural fluctuations of cytochrome P450CAM studied with molecular dynamics simulations. Biophysical Journal 74(2 PART 2): A236, Feb

Wakisaka, G., 1964: Studies On Platelet Antibodies In Idiopathic Thrombocytopenic Purpura And Experimental Thrombocytopenias. Nihon Ketsueki Gakkai Zasshi 27: 663-680

Agnolucci, M.T.; Nava, C., 1964: Histopathologic observations on experimental liver damage "From autologous Liver" (In the Rat). Il Fegato 10: 419-432

Kaczorowski, R., 1999: Connected care. The Andover Working Group. Hospital Quarterly 1(3): 49-52

Kononenko N.I.; Shcherbatko A.D., 1985: Effect of increase of intracellular calcium concentration on the transmembrane current induced by iontophoretic injection of cyclic amp in helix pomatia neurons. The effect of intracellular Ca2+ concentration increase on transmembrane current induced by cAMP injection into a neuron (cAMP-current) was studied on H. pomatia neurons under voltage clamp conditions. The elevation of intracellular Ca2+ concentra...

Canessa M.; Adragna N.; Falkner B., 1982: Measurements of sodium transport in red cells of black patients with essential hypertension. Federation Proceedings 41(5): ABSTRACT 8133

Huchzermeyer, F.W.; Gerdes, G.H., 1993: Newcastle disease virus isolated from ostriches in South Africa. Journal of the South African Veterinary Association 64(4): 140-140

Peters, R.P.H.; Mohammadi, T.; Vandenbroucke-Grauls, C.M.J.E.; Danner, S.A.; van Agtmael, M.A.; Savelkoul, P.H.M., 2004: Detection of bacterial DNA in blood samples from febrile patients: underestimated infection or emerging contamination?. We applied real-time broad-range polymerase chain reaction (PCR) to detect bacteraemia in blood from febrile patients. Interpretation of amplification results in relation to clinical data and blood culture outcome was complex, although the reprodu...