+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effect of aqueous extract of Bulbine natalensis Baker stem on haematological and serum lipid profile of male Wistar rats

, : Effect of aqueous extract of Bulbine natalensis Baker stem on haematological and serum lipid profile of male Wistar rats. Indian Journal of Experimental Biology 47(4): 283-288

Bulbine natalensis stem extract (25, 50 and 100 mg/kg body weight for 14 days) did not significantly alter the red blood cell count, haemoglobin, packed cell volume, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration and red cell distribution width in male Wistar rats. In contrast, the white blood cell count increased by the end of the experimental period. While the levels of neutrophils, lymphocytes and eosinophils decreased after the administration of single dose of the extract (day 1), those of the platelets and monocytes increased. The extract also reduced the levels of basophils and large unstained cells after the seven daily doses. All the doses increased the serum concentrations of cholesterol and triacylglycerols. Whereas the serum concentration of low-density lipoprotein was unaffected throughout the experimental period, the decrease in high-density lipoprotein cholesterol was accompanied by increase in the atherogenic index. The results showed that aqueous extract of B. natalensis stem exhibited localized systemic toxicity mainly on the white blood cell count and related indices. The alterations in the serum lipid profile may predispose the animals to atherosclerosis especially when consumed repeatedly for two weeks.


PMID: 19382725

Other references

Yoshiura, K.I.hiro; Noda, Y.; Kinoshita, A.; Niikawa, N., 2000: Colocalization of doublecortin with the microtubules: An ex vivo colocalization study of mutant doublecortin. Doublecortin (DCX) plays an important role in neuronal migration and development, and the participation of DCX in neuronal migration has been demonstrated by intensive mutational analysis for patients with X-linked or sporadic lissencephaly, and/o...

Mackenzie, J.W.; Furtick, W.R.; Bond, C.E., 1971: The activity of diquat on. Elodea densa Planch, as influenced by environmental factors and chemical combinations. In laboratory trials diquat showed decreasing speed of activity against E. densa with decreasing water temp, in the range 30 degrees C to 10 degrees C. The addition of low concns. of copper sulfate pentahydrate or disodium endothal did not enhance...

Gulbrandson, Rr, 1984: Save clothing $$$ by relining coats & jackets. NDSU Extension Service ication North Dakota State University: 84 (HE-387)

Skrzypek, E.; Straley, S.C., 1993: Mutational analysis supports a role in virulence for V antigen of Yersinia pestis. Abstracts of the General Meeting of the American Society for Microbiology 93(0): 46

Redman, J.F.; Arnold, W.C.; Smith, P.L.; Seibert, J.J., 1982: Hypertension and urino-thorax following an attempted percutaneous nephrostomy. Journal of Urology 128(6): 1307-1308

Mcfadden, G.H.; Weiser, H.H., 1938: A method for determining the action of certain organisms on nitrogen distribution in milk. The method is a modification of the Hiller and Van Slyke method. Sterilized skim milk is inoculated with 1 cc. of an active milk culture of Lactobacillus acidophilus and allowed to incubate for a desired period. The proteins are precipitated with...

Gmuca, S.; Lieberman, S.M.; Mehta, J., 2017: Pediatric Neuromyelitis Optica Spectrum Disorder and Sjögren Syndrome: More Common Than Previously Thought?. Journal of Rheumatology 44(6): 959-960

Rosas, R.; Croxatto, H., 1962: Vasoactive substances in blood and urine of DCA hypertensive rats. In a study of 20 pairs of rats it was found that production of anephro-tensin, a peptide of acid-incubated blood serum, was increased by dehydrocorticosterone acetate (DCA) treatment of 10 weeks or longer. Intravenous administration of this materi...

Mohapeloa, H.; Christiansen, O.B.; Grunnet, N., 1998: HLA-DR typing of women with recurrent late spontaneous abortion and unsuccessful cervical cerclage. The release of certain cytokines, e.g. tumour necrosis factor (TNF)-alpha, in the amniotic fluid has been suggested to be a cause of preterm birth. The predisposition to excessive liberation of cytokines from peripheral leukocytes has been shown t...

Harms-Ringdahl, M.; Anderstam, B.; Vaca, C., 1987: Heat-induced changes in the incorporation of [H3]acetate in membrane lipids. The effects of heat treatments at temperatures from 42 to 47 degrees C on the rate of incorporation of [3H]acetate into different classes of lipids have been studied in V-79 Chinese hamster cells. Thermotolerance induction and subtoxic heat treatm...