+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase Two

, : Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase Two. Thorax 65(6): 516-522

The increasing prevalence of asthma and allergy might be related to diet, particularly in Western countries. A study was undertaken to assess the association between dietary factors, asthma and allergy in a large international study including objective measurements of atopy. Between 1995 and 2005, cross-sectional studies were performed in 29 centres in 20 countries. Parental questionnaires were used to collect information on allergic diseases and exposure factors and data from 50 004 randomly selected schoolchildren (8-12 years, 29 579 with skin prick testing) were analysed. Random effect models for meta-analysis were applied to calculate combined ORs. Fruit intake was associated with a low prevalence of current wheeze in affluent (OR(adj) 0.86, 95% CI 0.73 to 1.02) and non-affluent countries (OR(adj) 0.71, 95% CI 0.57 to 0.88). Consumption of fish in affluent countries (OR(adj) 0.85, 95% CI 0.74 to 0.97) and of cooked green vegetables in non-affluent countries (OR(adj) 0.78, 95% CI 0.65 to 0.95) was associated with a lower prevalence of current wheeze. Overall, more frequent consumption of fruit, vegetables and fish was associated with a lower lifetime prevalence of asthma, whereas high burger consumption was associated with higher lifetime asthma prevalence. None of the food items was associated with allergic sensitisation. Except for fruit juice and fruit consumption, no associations were found with atopic wheeze. Food selection according to the 'Mediterranean diet' was associated with a lower prevalence of current wheeze and asthma ever (p(trend)=0.03). Diet is associated with wheeze and asthma but not with allergic sensitisation in children. These results provide further evidence that adherence to the 'Mediterranean diet' may provide some protection against wheeze and asthma in childhood.


PMID: 20522849

DOI: 10.1136/thx.2009.128256

Other references

Opere, C.A.; Tang, L.; A.Z.djali, K.H.; Ohia, S.E., 1994: Are retinal presynaptic prostanoid EP-3-receptors negatively coupled to adenylate cyclase?. Investigative Ophthalmology & Visual Science 35(4): 1887

Retzlaff, K.J., 2015: Don't fear the red pen: AORN journal editors are here to help. Aorn Journal 100(5): 461-463

Nachev Iv, 1969: Geologic development in the Balkan region during the late Alpine cycle. Spisanie na Bulgarskogo Geologichesko Druzhestvo 30(2): 163-174

Anonymous, 2010: Safer surgery: analysing behaviour in the operating theatre Rhona Flin Safer surgery: analysing behaviour in the operating theatre and Lucy Michell (Eds) Ashgate £75 482pp 9780754675365 9780754675365 [Formula: see text. SAFER SURGERY is an expertly edited body of research that looks at the behaviour and outcomes of teams working behind closed doors in surgery and anaesthesia from all perspectives. As the World Health Organization focuses on patient safety in peri...

Sanz, Jús.; García-Vera, Mía.Paz.; Magán, Iés., 2010: Anger and hostility from the perspective of the Big Five personality model. This study was aimed at examining the relationships of the personality dimensions of the five-factor model or Big Five with trait anger and with two specific traits of hostility (mistrust and confrontational attitude), and identifying the similari...

Shin, D.; Nagarajan, R., 2017: Enzymatic Assays to Investigate Acyl-Homoserine Lactone Autoinducer Synthases. Bacteria use chemical molecules called autoinducers as votes to poll their numerical strength in a colony. This polling mechanism, commonly referred to as quorum sensing, enables bacteria to build a social network and provide a collective response...

Redrejo-Rodríguez, M.; Ishchenko, A.A.; Saparbaev, M.K.; Salas, Mía.L.; Salas, Jé., 2009: African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. African swine fever virus (ASFV) encodes an AP endonuclease (pE296R) which is essential for virus growth in swine macrophages. We show here that the DNA repair functions of pE296R (AP endonucleolytic, 3'-->5' exonuclease, 3'-dies...

Bourges F., 1993: Emplacement of a vein system during the Birrimian; the example of gold-bearing quartz veins in Gangaol, Burkina Faso. Publication Occasionnelle - Centre International Pour la Formation et les Echanges Geologiques = Occasional Publication - International Center for Training and Exchanges in the Geosciences 23: 119-123

Robinson, D.P.; Das, S.; Searle, M.P., 2010: Earthquake fault superhighways. Motivated by the observation that the rare earthquakes which propagated for significant distances at supershear speeds occurred on very long straight segments of faults, we examine every known major active strike-slip fault system on land worldwid...

Ogawa, K.; Matsumura, N.; Yoshida, A., 2015: Modified osteotomy for symptomatic malunion of the humeral greater tuberosity. Here, we describe a modified osteotomy for malunion of the greater tuberosity that facilitates bone union and prevents symptom recurrence. The 3 most important features of this technique are: (1) osteotomizing the displaced fragment that includes...