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Effect of inhomogeneities and source position on dose distribution of nucletron high dose rate Ir-192 brachytherapy source by Monte Carlo simulation

, : Effect of inhomogeneities and source position on dose distribution of nucletron high dose rate Ir-192 brachytherapy source by Monte Carlo simulation. Journal of Cancer Research and Therapeutics 6(1): 54-57

The presence of least dense dry air and highly dense cortical bone in the path of radiation and the position of source, near or far from the surface of patient, affects the exact dose delivery like in breast brachytherapy. This study aims to find out the dose difference in the presence of inhomogeneities like cortical bone and dry air as well as to find out difference of dose due to position of source in water phantom of high dose rate (HDR) 192 Ir nucletron microselectron v2 (mHDRv2) brachytherapy source using Monte Carlo (MC) simulation EGSnrc code, so that the results could be used in Treatment Planning System (TPS) for more precise brachytherapy treatment. The settings and design are done using different software of the computer. For this study, the said source, water phantom of volume 30 x 30 x 30 cm 3, inhomogeneities each of volume 1 x 2 x 2 cm3 with their position, water of water phantom and position of source are modeled using three-dimensional MC EGSnrc code. Mean and probability are used for results and discussion. The % relative dose difference is calculated here as 5.5 to 6.5% higher and 4.5 to 5% lower in the presence of air and cortical bone respectively at transverse axis of the source, which may be due to difference of linear attenuation coefficients of the inhomogeneities. However, when the source was positioned at 1 cm distance from the surface of water phantom, the near points between 1 to 2 cm and 3 to 8 cm. from the source, at its transverse axis, were 2 to 3.5% and 4 to 16% underdose to the dose when the source was positioned at mid-point of water phantom. This may be due to lack of back scatter material when the source was positioned very near to the surface of said water phantom and overlap of the additional cause of missing scatter component with the primary dose for near points from the source. These results were found in good agreement with literature data. The results can be used in TPS.


PMID: 20479548

DOI: 10.4103/0973-1482.63567

Other references

Islas F., 1968: Biological observations on the pine g bark beetle dendroctonus adjunctus coleoptera scolytidae dendroctonus frontalis pinus hartweggi g mexico. Boletin Tecnico Instituto Nacional de Investigaciones Forestales Mexico (25): 1-21

Hollosy, K., 1957: The tuberculotic mamma. Tuberkulozis 10(1-2): 21-24

Smirnov F.L.; Marshintsev V.K.; Moskvitina L.V.; Uskov M.N., 1976: The typomorphic characteristics of apatite from deposits and occurrences on the Aldan Shield. Pages 5-31 1976

McEachin, R.C.; Keller, B.J.; Zandi, P.P.; Almani, M.; McInnis, M.G., 2008: Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE). Complex diseases are characterized by multiple genetic and environmental influences on disease susceptibility. Since the multiple genetic influences converge on a single phenotype, some commonality may be evident among genes that influence the dis...

de Bros, E., 1985: Liste der beobachteten und nach Fotos () bestimmten Arten, Exkursion-Grenzacherhorn vom 17.6.84. Mitteilungen der Entomologischen Gesellschaft Basel, 354: 154-156

Szabo, Balazs., 1998: Data for the burden caused by lead and cadmium in wildfowls the study of differences between the sexes and the species Adatok nehany vadlud es vadrece faj olomes kadmiumterheltsegehez az ivarok es a fajok kozotti kulonbsegek vizsgalata. Ornis Hungarica, 8: 95-99 (Suppl 1

Torregrosa, J.V.; Campistol, J.M.; Fenollosa, B.; Montesinos, M.; Romar, A.; Martinez de Osaba, M.J., 1996: Role of secondary hyperparathyroidism in the development of post-transplant acute tubular necrosis. Post-transplant cure tubular necrosis (ATN) represents the most frequent cause of delayed graft function in the immediate post-transplant period. Several causes have been associated with the development of post-transplant ATN such as donor and rec...

Green; Baird; Gibb, 2000: Reduced-symmetry deep-cavity cavitands. The syntheses of reduced-symmetry deep-cavity cavitands by two-stage stereoselective bridging with substituted benzal bromides is reported. Conditions for the optimal formation of the trisbridged derivatives were readily established. However, it w...

Iwanowa, T.S., 1958: Structure of type II nerve cells according to Dogiel. Zeitschrift für Mikroskopisch-Anatomische Forschung 63(4): 523-528

Dumitru, C.; Chan, S.M.H.; Turcanu, V., 2012: Role of Leukotriene Receptor Antagonists in the Management of Pediatric Asthma. At present, the main indications for leukotriene receptor antagonists (LTRA) in pediatric asthma are as add-on therapy to inhaled corticosteroids (ICS) and as initial controller therapy in children with mild asthma, especially those who cannot or...