+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effectiveness of breathing through nasal and oral routes in unconscious apneic adult human subjects: a prospective randomized crossover trial

, : Effectiveness of breathing through nasal and oral routes in unconscious apneic adult human subjects: a prospective randomized crossover trial. Anesthesiology 115(1): 129-135

The authors hypothesized that mouth ventilation by a resuscitator via the nasal route ensures a more patent airway and more effective ventilation than does ventilation via the oral route and therefore would be the optimal manner to ventilate adult patients in emergencies, such as during cardiopulmonary resuscitation. They tested the hypothesis by comparing the effectiveness of mouth-to-nose breathing (MNB) and mouth-to-mouth breathing (MMB) in anesthetized, apneic, adult subjects without muscle paralysis. Twenty subjects under general anesthesia randomly received MMB and MNB with their heads placed first in a neutral position and then an extended position. A single operator performed MNB and MMB at the target breathing rate of 10 breaths/min, inspiratory:expiratory ratio 1:2 and peak inspiratory airway pressure 24 cm H₂O. A plethysmograph was used to measure the amplitude change during MMB and MNB. The inspiratory and expiratory tidal volumes during MMB and MNB were calculated retrospectively using the calibration curve. All data are presented as medians (interquartile ranges). The rates of effective ventilation (expired volume > estimated anatomic dead space) during MNB and MMB were 91.1% (42.4-100%) and 43.1% (42.5-100%) (P < 0.001), and expired tidal volume with MMB 130.5 ml (44.0-372.8 ml) was significantly lower than with MNB 324.5 ml (140.8-509.0 ml), regardless of the head position (P < 0.001). Direct mouth ventilation delivered exclusively via the nose is significantly more effective than that delivered via the mouth in anesthetized, apneic adult subjects without muscle paralysis. Additional studies are needed to establish whether using this breathing technique during emergency situations will improve patient outcomes.


PMID: 21572315

DOI: 10.1097/ALN.0b013e31821d6c69

Other references

Gary, NE.; Witherell, PC.; Lorenzen, K., 1980: Distribution of foraging honey bees to multiple, small floral plots of various species. Using Gary's magnetic tag retrieval method [AA 444/72] the distribution of bees from 955 colonies in 28 apiaries was studied on 35 plots within an area of 60 km. On plots of lucerne (Medicago sativa), white clover (Trifolium repens), Lippia n...

Bezmen N.I.; Zharikov V.A.; Koshemchuk S.K.; Suk N.I., 1990: Water and hydrogen solubility in an albite melt (1200 degrees C, 2 kbar). Pages 10-11 1990

Podesta, H.A.; Ruiz, J., 1971: Diabetic arteriopathy and its differential diagnosis with arteriosclerosis. Prensa Medica Argentina 58(11): 559-568

Obade,P.T.; Koedam,N.; Soetaert,K.; Neukermans,G.; Bogaert,J.; Nyssen,E.; Nedervelde,F.van; Berger,U.; Dahdouh-Guebas,F., 2008: Impact of anthropogenic disturbance on a mangrove forest assessed by a 1D cellular automaton model using Lotka-Volterra-type competition. Mangrove forests are ecologically and economically important and frequently dominating protected coastal areas in the tropics and subtropics at suitable intertidal zones and are often subjected to disturbances that disrupt the structure of an ecos...

Villegente, M.; Marmey, P.; Job, C.; Galland, M.; Cueff, G.; Godin, Béatrice.; Rajjou, Lïc.; Balliau, T.; Zivy, M.; Fogliani, B.; Sarramegna-Burtet, Vérie.; Job, D., 2017: A Combination of Histological, Physiological, and Proteomic Approaches Shed Light on Seed Desiccation Tolerance of the Basal Angiosperm Amborella trichopoda. Desiccation tolerance allows plant seeds to remain viable in a dry state for years and even centuries. To reveal potential evolutionary processes of this trait, we have conducted a shotgun proteomic analysis of isolated embryo and endosperm from m...

Sakamoto, S., 1967: Cytogenetic studies in the tribe Triticeae. V. Intergeneric hybrids between two Eremopyrum species and Agro-pyron tsukushiense. The following pentaploid hybrids were produced: (1) A. buonapartis var. buonapartis x A. tsukushiense, (2) A. buonapartis var. sublanuginosum x A. tsukushiense and (3) A. orientale x A. tsukushiense. All F1S were perennial and showed complete poll...

Uqvist, J.; Kolmodin, K., 2002: Computational modelling of protein tyrosine phosphatase reactions. Abstracts of Papers American Chemical Society 223(1-2): PHYS 83

Anonymous, 2001: Canadian Cardiovascular Society 2000 Consensus Conference: Women and Ischemic Heart Disease. Canadian Journal of Cardiology 17 Suppl D: 3d-69d

Beaton, L.A.; Marro, L.; Malone, S.; Samiee, S.; Grimes, S.; Malone, K.; Wilkins, R.C., 2013: Investigating γ H2AX as a Biomarker of Radiosensitivity Using Flow Cytometry Methods. Background and Purpose. This project examined the in vitro   γ H2AX response in lymphocytes of prostate cancer patients who had a radiosensitive response after receiving radiotherapy. The goal of this project was to determine whether the γ H...

Grako, K.A.; Anderson, C.M., 1999: Inhibition of mitochondrial-produced ATP contributes to insulin resistance. Diabetes 48(SUPPL 1): A448