geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Endometrial and conceptus expression of HoxA10, transforming growth factor beta1, leukemia inhibitory factor, and prostaglandin H synthase-2 in early pregnant pigs with gonadotropin-induced estrus


, : Endometrial and conceptus expression of HoxA10, transforming growth factor beta1, leukemia inhibitory factor, and prostaglandin H synthase-2 in early pregnant pigs with gonadotropin-induced estrus. Domestic Animal Endocrinology 38(4): 222-234

This study was conducted to evaluate the effect of estrus induction with gonadotropins on endometrial and conceptus expression of HoxA10, transforming growth factor (TGF) beta1, leukemia inhibitory factor (LIF), and prostaglandin H synthase-2 (PGHS-2) during early pregnancy in pigs. Twenty-four prepubertal gilts received 750 IU of pregnant mare serum gonadotropin (PMSG) and 500 IU of human chorionic gonadotropin (hCG) 72h later. Gilts in the control group (n=23) were observed daily for estrus behavior. Endometrial tissue samples, conceptuses, blood serum, and uterine luminal flushings (ULFs) were collected on days 10, 11, 12, and 15 after insemination. There was no effect of estrus induction on estradiol content in ULFs, or on ovulation and fertilization rates in studied gilts. However, the content of progesterone in the blood serum was greater in naturally ovulated gilts in comparison to gonadotropin-treated animals on day 12 of pregnancy (P<0.05). HoxA10 expression was up-regulated in the endometrium of pregnant gilts, with natural ovulation on days 12 (P<0.05) and 15 (P<0.001) in comparison to days 10 and 11. When compared to control gilts, administration of PMSG/hCG resulted in decreased expression of endometrial HoxA10, TGFbeta, LIF, and PGHS-2 on day 12 of pregnancy (P<0.05). Conceptus expression of studied factors was not affected by gonadotropin treatment. Overall, these results suggest improper endometrial preparation for implantation in prepubertal gilts induced to ovulate with PMSG/hCG.

US$19.90

PMID: 20022444

DOI: 10.1016/j.domaniend.2009.11.001


Other references

Wilson, L.A.; Rocha Herrera, A.; Green, N.K.; Myers, D.J., 1994: Influence of conventional and microwave heating on the aroma, flavor and hotness of spices in foods. Abstracts of Papers American Chemical Society 208(1-2): AGFD 132

Gandemer, G.; Pascal, G.; Durand, G., 1983: Lipogenic capacity and relative contribution of the different tissues and organs to lipid synthesis in male rat. The rates of 3H from 3H2O incorporation into total lipids and fatty acids were measured in vivo in the different organs and tissues of 7-wk old male Wistar rats to compare the lipogenic capacity of those organs and tissues and to determine their r...

Gayathri Gopalakrishnan; MARI.C.istina Negri; William Salas, 2012: Modeling biogeochemical impacts of bioenergy buffers with perennial grasses for a row-crop field in Illinois. Current research on the environmental sustainability of bioenergy has largely focused on the potential of bioenergy crops to sequester carbon and mitigate greenhouse gas emissions and possible impacts on water quality and quantity. A key assumptio...

Qi, H-mei.; Jin, Y.; Duan, Z-jun.; Ye, X-hua.; Cheng, W-xia.; Zhu, L., 2011: Molecular epidemiology of human adenovirus diarrhea among infants and young children in Lanzhou from July 2005 to June 2008. Gastroenteritis is a major cause of childhood morbidity and mortality worldwide. Adenovirus AdV is recognized to be one of the most important pathogens associated with severe dehydrating gastroenteritis. Studies reported elsewhere have shown that...

Bawtree, R.F., 1965: Turtle dove displaying to collared dove. British Birds, 58: 299

Elsing, C.; Fitscher, B.A.; Böker, C.; Kramer, W.; Stengelin, S.; Stremmel, W., 1999: Expression of a bile acid transporter in biliary epithelial cells from normal and cholestatic rat livers. A sodium dependent bile acid carrier has recently been cloned and characterized in rat ileum. The present study demonstrates the presence of a mRNA species specific for the rat ileal bile acid carrier (r-IBAT) in rat biliary epithelial cells. More...

Yu, F.X.; Sun, H.Q.; Janmey, P.A.; Yin, H.L., 1992: Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin. Gelsolin is an actin filament-severing and -capping protein that has profound effects on actin filament organization and assembly. It is activated by Ca2+ and inhibited by polyphosphoinositides (PPI). We have previously shown that PPI inhibit acti...

Salvati, M.E.; Balog, A.; Shan, W.; Wei, D.D.; Pickering, D.; Attar, R.M.; Geng, J.; Rizzo, C.A.; Gottardis, M.M.; Weinmann, R.; Krystek, S.R.; Sack, J.; An, Y.; Kish, K., 2004: Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists. A novel series of isoindoledione based compounds were identified as potent antagonists of the androgen receptor (AR). Co-crystallization of members of this family of inhibitors was successfully accomplished with the T877A AR LBD. A working model o...

Schopp, Ralph, 1936: Observations on life history of lily bulb thrips, Liothrips vaneeckei Priesner. In the natural development of this insect, as determined by a study of the proportions of stages in natural population samples taken at regular intervals, there are 2 groups progressing from the 2 predominant overwintering stages. An alternation o...

Hyland, M.E.; Kenyon, C.A., 1992: Mood variability in asthmatic patients: a case report. British Journal of General Practice 42(362): 395-395