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Extraesophageal manifestations of gastroesophageal reflux disease

, : Extraesophageal manifestations of gastroesophageal reflux disease. Gastroenterology Clinics of North America 42(1): 71-91

This article discusses the current state of knowledge regarding the relationship between gastroesophageal reflux disease (GERD) and pulmonary and ear/nose/throat manifestations of reflux and outlines the recent developments in the diagnostic and treatment strategies for this difficult group of patients. Upper gastrointestinal endoscopy and pH monitoring are poorly sensitive for diagnosing reflux in this group of patients. Instead it is recommended that in those without warning symptoms, an empiric trial of proton-pump inhibitors be the initial approach to diagnosing and treating the potential underlying cause of these extraesophageal symptoms.


PMID: 23452632

DOI: 10.1016/j.gtc.2012.11.004

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