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Factors associated with the non-completion of conventional anti-tuberculosis treatment in Peru

, : Factors associated with the non-completion of conventional anti-tuberculosis treatment in Peru. Archivos de Bronconeumologia 48(5): 150-155

The non-adherence to tuberculosis treatment is associated with increased infection, antibiotic resistance, increased costs and death. Our objective was to identify factors associated with lack of completion of conventional treatment for tuberculosis in Peru. An unmatched case-control study in patients diagnosed with tuberculosis from 2004-2005 who completed treatment until September 2006. The cases were defined as patients who discontinued treatment for ≥30 consecutive days, while the controls were defined as those who completed treatment without interruption. The factors were identified by logistic regression, calculating odds ratios (OR) and 95% confidence intervals (CI). We studied 265 cases and 605 controls. The non-adherence to treatment in our study was associated with the male sex (OR=1.62; CI: 1.07-2.44), having felt discomfort during treatment (OR=1.76; CI: 1.19-2.62), a prior history of non-compliance (OR=7.95; CI: 4.76-13.27) and illegal drug use (OR=3.74; CI: 1.25-11.14). Also, if we consider the interaction of previous non-adherence history and poverty, the risk of non-completion increases (OR=11.24; CI: 4-31.62). Conversely, having been properly informed about the disease (OR=0.25; CI: 0.07-0.94) and being able to access health-care services within office hours (8 am-8 pm) (OR=0.52; CI: 0.31-0.87) were associated with better adherence. The non-compliance with anti-tuberculosis treatment was associated with non-modifiable factors (male sex, previous non-compliance) and with others whose control would improve compliance (malaise during treatment, illegal drug use and poverty). Likewise, providing access to the health-care system and improving the information given about tuberculosis should be priorities.


PMID: 22377140

DOI: 10.1016/j.arbres.2011.12.008

Other references

Smith, S.A.; Williams, M.A.; Mitchell, J.H.; Mammen, P.P.A.; Garry, M.G., 2005: The capsaicin-sensitive afferent neuron in skeletal muscle is abnormal in heart failure. Background - In heart failure, the cardiovascular response to activation of the skeletal muscle exercise pressor reflex (EPR) is exaggerated. Group IV afferent neurons, primarily stimulated by the metabolic by-products of skeletal muscle work, con...

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Wright Kate; Cygan Randall T.; Slater Ben, 2002: Impurities and nonstoichiometry in the bulk and on the (1014) surface of dolomite. Atomistic computer simulation methods have been used to model the nature of nonstoichiometry and impurity defects in the bulk and at the (1014) surface of dolomite (MgCa(CO (sub 3) ) (sub 2) ). Calcium and Mg in the bulk and at the surface have be...

Miatello, V.R.; Medel, R.; Machado, E., 1958: Renal needle-biopsy: personal experience in 250 punctures. Revista Argentina de Urologia 27(1-3): 81-82

Woelke, Charles, 1962: Inspection of Japanese oyster seed. Pacific Mar Fish Comm Annu Rep 1961 14: 48-50

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Watanabe, T.; Aoki, S.; Ohta, S.; Shirono, K.; Tanaka, A., 1999: Anti-bacterial film suitable for food packaging. Official Gazette of the United States Patent & Trademark Office Patents 1224(4), Jul 27

Turnaev, I.I.; Gunbin, K.V.; Afonnikov, D.A., 2015: Plant auxin biosynthesis did not originate in charophytes. Trends in Plant Science 20(8): 463-465

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