geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Feasibility of commercial interferon-gamma-based methods for the diagnosis of latent Mycobacterium tuberculosis infection in Finland, a country of low incidence and high bacille Calmette-Guérin vaccination coverage


, : Feasibility of commercial interferon-gamma-based methods for the diagnosis of latent Mycobacterium tuberculosis infection in Finland, a country of low incidence and high bacille Calmette-Guérin vaccination coverage. Clinical Microbiology and Infection 13(8): 836-838

The performances of the QuantiFERON-TB Gold in Tubes (QFGT), T SPOT-TB (ELISPOT) and the Mantoux test were compared for the diagnosis of latent tuberculosis infection in Finland, a country of low tuberculosis incidence. In Cohort A (16 students), freshly isolated peripheral blood mononuclear cells (PBMCs), and in Cohort B (21 school children), cryopreserved PBMCs, were used for the ELISPOT assay. Cryopreservation of cells in fetal calf serum, but not in serum-free medium, produced false-positive results. Discrepancies between the results of the assays were observed. It was concluded that the accuracy of these ex-vivo methods needs additional evaluation.

US$19.90

PMID: 17501976

DOI: 10.1111/j.1469-0691.2007.01750.x


Other references

Kirsch, J.; Barber, N.; Herbert, C.; Nejdl, R., 1982: Mercy or murder: a death at Kaiser hospital. California Magazine 7(11): 78-81, 164-165+

Smirnova, S.; Khovanova, E.; Sharupich, E., 1984: Comparative study of the H. factor in Drosophila simulans and some instability factors in Drosophila melangaster. Soviet genetics 20(1): 46-52

dos Santos, C.E.; Biondi, J.C.rlos, 2011: Utilizacao de elipsoide de anisotropia variografica como indicador cinematico em macicos rochosos fragmentados por falhas; o exemplo do deposito de asbestos crisotila Cana Brava Minacu, GO. The parameters of a variogram depend on which direction it is calculated, such as the ellipsoid of variographic anisotropy, whose axes indicate the directions of higher, medium and lower continuity of the variable used to calculate the variogram....

Feldhamer, G.A.; Gates, J.E.; Harman, D.M.; Loranger, A.J.; Dixon, K.R., 1986: Effects of interstate highway fencing on white-tailed deer activity. Locations of white-tailed deer (Odocoileus virginianus ) along a 41.4-km section of Interstate 84 (I-84) right-of-way in Pike County, Pennsylvania, were determined by radio telemetry and spotlight surveys. Bucks crossed roads more often (P 0.05) b...

Siddiqui, M.Asif.A.; Perry, C.M., 2006: Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil). Human papillomavirus (HPV) quadrivalent recombinant vaccine is a mixture of virus-like particles derived from the L1 capsid proteins of HPV types 6, 11, 16 and 18. It is administered intramuscularly in a three-dose regimen, with the initial inject...

Kalenich, F.S., 1976: The effectiveness of fungicides against apple powdery mildew. Dispersion analysis was used to determine the effectiveness of several organic fungicides against powdery mildew [Podosphaera leucotricha] on apples. All those tested gave good control but the best results were given by benomyl.

Skreb, N., 1957: Etudes cytologiques sur l'oeuf de quelques Cheiropteres. Archives de Biologie Paris, 68: 381-428

Israel Society For Physiology And Pharmacology, 1997: Annual Meeting of the Israel Society for Physiology and Pharmacology. This meeting contains abstracts of 19 papers written in English.

Boshoff, C.; Weiss, R.A., 1998: Kaposi's sarcoma-associated herpesvirus. Kaposi's sarcoma (KS) is a vascular tumor predominantly found in the immunosuppressed. Epidemiologic studies suggest that an infective agent is the etiologic culprit. Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus-8...

Takai, H.; Nakayama, Y.; Kim, D-Soon.; Arai, M.; Araki, S.; Mezawa, M.; Nakajima, Y.; Kato, N.; Masunaga, H.; Ogata, Y., 2007: Androgen receptor stimulates bone sialoprotein (BSP) gene transcription via cAMP response element and activator protein 1/glucocorticoid response elements. Bone sialoprotein (BSP) is an early marker of osteoblast differentiation. Androgens are steroid hormones that are essential for skeletal development. The androgen receptor (AR) is a transcription factor and a member of the steroid receptor superf...