geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

First-in-man experience of percutaneous aortic valve replacement using self-expanding corevalve prosthesis


, : First-in-man experience of percutaneous aortic valve replacement using self-expanding corevalve prosthesis. Indian Heart Journal 63(3): 241-244

Percutaneous aortic valve replacement is a new emerging method for nonsurgical replacement of aortic valve in patients with severe aortic stenosis. We report the first-in-man case of percutaneous aortic valve replacement with self-expanding Core Valve aortic prosthesis. The procedure was performed on 12 July 2004 on a 62 years patient with severe aortic stenosis (peak systolic gradients across aortic valve being 90 mm Hg), moderately severe aortic regurgitation and preserved left ventricular systolic function. The patient had associated morbidities like renal failure (raised blood urea nitrogen and serum creatinine levels) and end-stage carcinoma of lung. Valve implantation was performed under general anesthesia with extracorporeal support using the retrograde approach. The patient was adequately screened prior to the procedure. The device was implanted successfully with post implantation peak systolic gradient across aortic valve being only 16 mm Hg. However, this patient died after four days due to renal failure and bleeding diathesis leading to multiorgan failure. Percutaneous implantation of self-expanding CoreValve prosthesis in patients with severe aortic stenosis with or without aortic regurgitation is feasible. Long-term studies will determine its future.

US$29.90

PMID: 22734343


Other references

Alberts P.; Ogren V.R.; Sellstrom A.I., 1985: Role of cyclic amp in adrenoceptor mediated control of tritiated noradrenaline secretion in guinea pig ileum myenteric nerve terminals. Secretion of 3H-noradrenaline was evoked by electrical field stimulation (1 Hz, 300 shocks) in guinea-pig ileum myenteric plexus. The role of cyclic nucleotides in the presynaptic receptor-mediated control of 3H-noradrenaline secretion was studied...

Krízová, B.; Sochman, J., 2007: Repeated thrombosis of the mechanical heart valve prosthesis. Paper presents the cause of 54-year-old patient with implanted mechanical heart valve prosthesis in the mitral position admitted to the hospital with a serious left ventricle (LV) systolic dysfunction. Patient underwent repeated attacks of acute l...

Kumar, A.Sampath., 2009: Invited commentary. Annals of Thoracic Surgery 88(3): 745-745

Setiadi, T.S.achri, M.H.rdjo, S., 1975: The effect of sorbic acid addition and packaging using polyethylene wraps on the keeping quality of the quick salted fish cakes. Teknologi hasil pertanian: 13 1-13

Mumenthaler, M.; Probst, C.; Mumenthaler, A.; Weber, B.G.; Schnyder, J., 1964: Tarsal-Tunnel Syndrome. Schweizerische Medizinische Wochenschrift 94: 373-382

Brewster, A.M.; Jorgensen, T.J.; Ruczinski, I.; Huang, H.Y.; Hoffman, S.; Thuita, L.; Newschaffer, C.; Lunn, R.M.; Bell, D.; Helzlsouer, K.J., 2005: Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relationship to breast cancer risk and familial predisposition to breast cancer. Family history is a risk factor for breast cancer and could be due to shared environmental factors or polymorphisms of cancer susceptibility genes. Deficient function of DNA repair enzymes may partially explain familial risk as polymorphisms of DN...

Cheli, F.; Campagnoli, A.; Tognon, G.; Pinotti, L.; Baldi, A.; Savoini, G.; Dell'Orto, V., 2005: Wholesomeness of feed determined by electronic nose. The operation of the electronic nose is explained and the instrument illustrated by a photograph and a diagram. By analysing odours and aromas, the device provides a rapid, objective and reliable assessment of the quality of animal feed. The devic...

Barnwell G.M.; Cerimele B.J., 1973: Further studies of the effects of varying spatio temporal patterns of dendritic input potentials on neuronal somatic potentials. Zimmerman, Stuart O Abstracts Tenth Symposium on Biomathematics And Computer Science in The Life Sciences March 29-31, , Houston, Texas 85p University Of Texas: Health Science Center, Houston, Texas 62

Prout, C., 1991: Passing the buck. Nursing 4(40): 8-8

Floyd Earl, 1942: Some geological notes on Trinidad, Colorado. Rocks and Minerals 17(1): 3-7