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High-sensitivity brain SPECT system using cadmium telluride (CdTe) semiconductor detector and 4-pixel matched collimator


, : High-sensitivity brain SPECT system using cadmium telluride (CdTe) semiconductor detector and 4-pixel matched collimator. Physics in Medicine and Biology 58(21): 7715-7731

For high-sensitivity brain imaging, we have developed a two-head single-photon emission computed tomography (SPECT) system using a CdTe semiconductor detector and 4-pixel matched collimator (4-PMC). The term, '4-PMC' indicates that the collimator hole size is matched to a 2 × 2 array of detector pixels. By contrast, a 1-pixel matched collimator (1-PMC) is defined as a collimator whose hole size is matched to one detector pixel. The performance of the higher-sensitivity 4-PMC was experimentally compared with that of the 1-PMC. The sensitivities of the 1-PMC and 4-PMC were 70 cps/MBq/head and 220 cps/MBq/head, respectively. The SPECT system using the 4-PMC provides superior image resolution in cold and hot rods phantom with the same activity and scan time to that of the 1-PMC. In addition, with half the usual scan time the 4-PMC provides comparable image quality to that of the 1-PMC. Furthermore, (99m)Tc-ECD brain perfusion images of healthy volunteers obtained using the 4-PMC demonstrated acceptable image quality for clinical diagnosis. In conclusion, our CdTe SPECT system equipped with the higher-sensitivity 4-PMC can provide better spatial resolution than the 1-PMC either in half the imaging time with the same administered activity, or alternatively, in the same imaging time with half the activity.

US$19.90

PMID: 24140804

DOI: 10.1088/0031-9155/58/21/7715


Other references

Ralph, D.A.; Langenbach, M., 1988: Oklahoma pharmacists' explanations of professional satisfaction and dissatisfaction. This study examined whether the theoretical constructs of role conflict and incomplete professionalization serve as valid explanations of pharmacists' professional satisfaction or dissatisfaction. A sample of registered pharmacists in Oklahom...

de la Messeliere, S.; Renard, G., 1987: The corneal endothelium of diabetic patients. A study using specular microscopy. As the endothelial cells of the human cornea cannot perform mitosis, any metabolic alteration that destroys the cells should result into a decrease in cell density. This study was designed to demonstrate this phenomenon in diabetics as we know tha...

Lim, S.; Jatakanon, A.; John, M.; Gilbey, T.; O'connor, B.J.; Chung, K.F.; Barnes, P.J., 1997: The effect of inhaled steroids on exhaled nitric oxide production, airway responsiveness and airway inflammatory parameters in asymptomatic steroid naive asthmatics. European Respiratory Journal Supplement 10(25): 106S, Sept

Passàli, D.; Biagini, C.; Pedace, E., 1996: Presumed physiopathology of the nasal wall surgery and contemporary techniques of the inferior turbinates surgery. The lateral wall of the nasal cavity is anatomically complex and covers several nasal functions: ventilation, conditioning of the air, protection. This region also plays a prime role in maintaining nasal-sinus homeostasis through dynamic regulatio...

Tait, J., 1926: Experiments and observations on Crustacea. Part VII. Some structural and physiological features of the Valviferous Isopod Chiridotea. Proceedings of the Royal Society of Edinburgh, 46: 334-348

Petta, C.A.; Faundes, A.; Dunson, T.R.; Ramos, M.; Delucio, M.; Faundes, D.; Bahamondes, L., 1998: Timing of onset of contraceptive effectiveness in Depo-Provera users: II. Effects on ovarian function. To ensure ovulation does not occur, it is recommended that Depo-Provera injections be administered within the first 7 days of the menstrual cycle. In some settings, this requirement acts as a barrier to women's free access to injectable contr...

Rzepecki W.; Lukasiewicz M.; Lukaszczyk E.; Harazda M., 1970: On the surgical treatment of myasthenia. Neurologia i Neurochirurgia Polska 20(3): 327-330

H.C.iJuan; G.B.oGen; Qian DeMing; Wang MingGen, 2001: Present situation of rice field weed occurrence and damage in Shanghai. The second general survey of rice field weed species, community structures and damage levels in Shanghai, China was carried out using the five-point sampling mode and the five-level visual observation method during 1998-99, and the survey data wer...

Vedresh, T., 1989: Equipment for obtaining cheese curd (cheesemaking machine). A fully automated cheesemaking machine is described. It is composed of an insulated heating and cooling tank, and equipment for cutting, mixing and washing the curd, as well as for whey drainage and separation, and discharge of cheese grains. The...

Vaz, Z., 1934: Trichonema (Cylico-stephanus) parvibursatum n. sp., nematoide parasito do intestino grosso de cavallo. Revista de Biologia e Hygiene Sao Paolo, 5: 71-74