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Holoprosencephaly in clomiphene-induced pregnancy: a possible association? A case report and literature review

, : Holoprosencephaly in clomiphene-induced pregnancy: a possible association? A case report and literature review. Clinical and Experimental Obstetrics & Gynecology 39(4): 535-536

Clomiphene is widely used for inducing ovulation. Evidence for congenital abnormalities, in particular central nervous system defects (CNS-D) and in babies born from clomiphene-induced pregnancies is conflicting. The authors report a case of holoprosencephalia (HPE) in a fetus delivered from a mother receiving clomiphene.


PMID: 23444763

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