+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hydroxylated bisabolol oxides: evidence for secondary oxidative metabolism in Matricaria chamomilla

, : Hydroxylated bisabolol oxides: evidence for secondary oxidative metabolism in Matricaria chamomilla. Journal of Natural Products 76(10): 1848-1853

German chamomile (Matricaria chamomilla) is one of the most popular medicinal plants used in Western herbal medicine. Among the various phytochemicals present in the essential oil of the flowers of German chamomile, bisabolol and its oxidized metabolites are considered as marker compounds for distinguishing different chemotypes. These compounds are influential in mediating the aroma of the essential oil of M. chamomilla and contribute to the therapeutic properties (anti-inflammatory, antibacterial, insecticidal, and antiulcer) of this species. In order to find other possible bisabolol derivatives as marker compounds for authentication of German chamomile in botanical and commercial products, an in-depth investigation using a GC-assisted fractionation procedure was performed on nonpolar fractions. As a result of this approach, three new hydroxylated derivatives of bisabolol oxides A and B (1-3) have been isolated from M. chamomilla. Plausible biogenetic pathways are presented.


PMID: 24070008

DOI: 10.1021/np4003349

Other references

Singer, Ca, 1993: Simulation models of climate change--January 1979-April 1993. Quick bibliography series US Department of Agriculture National Agricultural Library US: 993 (93-42)

Kerr, J.Z.; Berg, S.L.; Hausheer, F.; Blaney, S.M., 1999: Karenitecins Cytotoxicity studies in pediatric tumor cell lines. Proceedings of the American Association for Cancer Research Annual Meeting 40: 112, March

Butler R.J.F., 1984: Quality assurance in hospital dental practice. An analysis of established quality assurance mechanisms was undertaken with consideration given to their application in hospital dentistry. An outline is given of the approach pursued at the Westmead Center Dental Clinical School [Australia].

Göransson, K.; Lundberg, J.; Ljungqvist, O.; Ohlsson, E.; Sandblom, G., 2016: Safety hazards in abdominal surgery related to communication between surgical and anesthesia unit personnel found in a Swedish nationwide survey. Many adverse events occur due to poor communication between surgical and anesthesia unit personnel. The aim of this study was to identify strategies to reduce risks unveiled by a national survey on patient safety. During 2011-2015, specially train...

Howard, Jonathan, 1995: Forces generated by single molecules of the motor protein kinesin. Journal of Cellular Biochemistry Supplement 0(19B): 103

Meyer, R.; Bovey, R., 1988: Tebuthiuron formulation and placement effects on response of woody plants and soil residue. Tebuthiuron (N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-N,N'-dimethylurea] in various formulations and placements was applied to honey mesquite (Prosopis glandulosa Torr.

Morohashi, N.; Yamamoto, Y.; Kuwana, S.; Morita, W.; Shindo, H.; Mitchell, A., P.; Shimizu, M., 2006: Effect of sequence-directed nucleosorne disruption on cell-type-specific repression by alpha 2/Mcm1 in the yeast genorne. In Saccharomyces cerevisiae, a-cell-specific genes are repressed in MAT alpha cells by alpha 2/Mcm1, acting in concert with the Ssn6-Tup1 corepressors and the Isw2 chromatin remodeling complex, and nucleosome positioning has been proposed as one...

Yoneyama, Y.; Wakatsuki, M.; Sawa, R.; Kamoi, S.; Takahashi, H.; Shin, S.; Kawamura, T.; Power, G.G.; Araki, T., 1994: Plasma adenosine concentration in appropriate- and small-for-gestational-age fetuses. OBJECTIVE: Our purpose in this study was to investigate the relationship between fetal plasma adenosine concentration and catecholamine concentration, blood gases, and pH in appropriate- and small-for-gestational-age fetuses. STUDY DESIGN: Cordoce...

Kozlov, M.Ia.; Lukovskiĭ, R.V., 1984: Testing Eustachian tube patency before surgical correction of anomalies of the middle ear in children. Vestnik Otorinolaringologii: 54-56

Dadaci, M.; Karagülle, N.; Sönmez, E.; Dadaci, Z.; İşci, E.Tevfik.; İnce, B.; Vargel, İbrahim.; Pişkin, E.; Erk, A.Yücel., 2016: Evaluation of the effectiveness of biodegradable electrospun caprolactoneand poly(lactic acid-ε-caprolactone) nerve conduits for peripheral nerveregenerations in a rat sciatic nerve defect model. The aim of this study was to compare electrospun caprolactone (EC) and poly(lactic acid-ε-caprolactone) (PLCL) nerve conduits with nerve graft in a rat sciatic nerve defect model. A total of 32 male Wistar albino rats were divided into 4 groups,...