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Hypercohones D-G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens


, : Hypercohones D-G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens. Natural Products and Bioprospecting 4(2): 73-79

Four new polycyclic polyprenylated acylphloroglucinol type metabolites, hypercohones D-G (1-4), along with four known analogues (5-8), were isolated from the aerial parts of Hypericum cohaerens. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested.

US$19.90

PMID: 24859375

DOI: 10.1007/s13659-014-0007-5


Other references

Soares, M.P.; Usheva, A.; Brouard, S.; Berberat, P.O.; Gunther, L.; Tobiasch, E.; Bach, F.H., 2002: Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide. It is well established that expression of heme oxygenase-1 (HO-1) acts in a cytoprotective manner in a variety of cell types, including in endothelial cells (EC). We have recently shown that HO-1 expression protects EC from undergoing apoptosis. W...

Aarli, J.A., 1999: Late-onset myasthenia gravis: a changing scene. The prevalence of myasthenia gravis (MG) among middle-aged and older patients has increased. Patients with early-onset MG live longer than before, but there is also an increase in late-onset MG (onset of the disease after the age of 50 years in pa...

Dear, P.R.; Godfrey, D.J., 1985: Neonatal auditory brainstem response cannot reliably diagnose brainstem death. In two newborn infants who had experienced severe asphyxial insults, and who showed noticeable signs of brainstem dysfunction, all components of the auditory brainstem response except the eighth nerve potential became undetectable. Both babies sur...

Paterson, J.Y.F.; Sepulveda, F.V.; Smith, M.W., 1980: Stoichiometry vs. coupling ratio in the co transport of sodium and different neutral amino acids. The stoichiometry of Na coupling to amino acid movement across the brush border membrane of the rabbit distal ileum was determined under initial rate conditions. The coupling ratio, defined as the amino acid-dependent Na influx/the Na-dependent am...

Zwierzchowski, L.; Dymnicki, E.; Lukaszewicz, M.; Grochowska, R.; Oprzadek, J., 1997: Association of growth hormone polymorphism, growth, feed intake and feed conversion in Black-and-White cattle. Leucine/valine (L/V) polymorphism was genotyped in 265 young Black-and-White (BW) cattle of both sexes using PCR-RFLP technique. The frequency for L and V allele was 0.61 and 0.39, respectively. Growth performance and feed intake/conversion were s...

Pinto J.A.; Brewer D.B., 1974: Glomerular morphometry part 1 combined light microscope and electron microscope studies in normal rats. Laboratory Investigation 30(5): 657-663

Probst, R., 2013: Does modern speech audiometry belong in the assessment process?. Hno 61(1): 12-13

Haourigui, M.; Vallette, G.; Martin, M.E.ise; Sumida, C.; Benassayag, C.; Nunez, E.A., 1994: In vivo effect of free fatty acids on the specific binding of glucocorticosteroids to corticosteroid binding globulin and liver receptors in immature rats. Stimulating lipase activity with heparin (200 IU/kg b. w.) increased the plasma free fatty acid (FFA) concentration of immature rats (15 days). The effect of this elevated FFA concentration on glucocorticoid binding to corticosteroid binding globu...

Tetlow, M., 1974: Black-necked stilt at Town of Perinton, Monroe County, New York. Kingbird, 241: 13

Slapnicar, J.; Tocilj, D.; Dragnić, A.; Basić, J., 1980: Osteomyelitis in intramedullary fixation of closed fractures. Acta Chirurgica Iugoslavica 27 Suppl 1: 513-515