geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Improving the management of neuropathic pain


, : Improving the management of neuropathic pain. Practitioner 254(1731): 27-30, 3

Neuropathic pain is defined as 'pain arising as a direct consequence of a lesion or disease of the somatosensory system'. It may reflect a widespread neuropathic process (e.g. diabetic neuropathy) or a more focal disorder (e.g. post-herpetic neuralgia). The practical importance of recognising neuropathic pain (as distinct from nociceptive pain) lies in the difference in effective treatments. The patient may be experiencing more than one type of pain. Many long-term disabling neurological disorders, such as multiple sclerosis, as well as causing neuropathic pain, may also give rise to musculoskeletal pains which may be more readily amenable to treatment. Most treatment for long-term pain, including neuropathic pain, should be provided in primary care, with specialist support. When taking the history it is important to elicit information about the site, duration, intensity and character of the pain, or pains, and what precipitates and relieves it. Accompanying somatosensory disturbance in the painful territory (numbness; allodynia; hyperalgesia; paraesthesia and dysaesthesia) is strongly suggestive of neuropathic pain. A specialist opinion should be sought where the diagnosis is uncertain, or the patient's condition is rapidly deteriorating or uncontrolled. This may be a specialist in a particular condition, to address issues of primary diagnosis, or a specialist in pain medicine to advise on, or provide, further treatment. Patients who are struggling with their pain are best served by specialist centres that can endeavour to explain the condition and encourage self-management.

US$29.90

PMID: 20812611


Other references

Herrera, J.de.J., 1980: Suppression of the thyroid by triiodothyronine. Boletin de la Asociacion Medica de Puerto Rico 72(9): 466-468

Hoese, DF.; Allen, GR., 1983: A review of the gudgeon genus Hypseleotris Pisces Eleotridae of Western Australia, with descriptions of three new species. Records of the Western Australian Museum, 103: 243-261

Gajdos P.; Nouailhat F.; Barois A.; Goulon M., 1970: Circulatory collapse during poisoning with barbiturates tranquilizers and phenothiazine. Annales de Medecine Interne 121(8-9): 661-672

Potchter, O.; Goldman, D.; Iluz, D.; Kadish, D., 2012: The climatic effect of a manmade oasis during winter season in a hyper arid zone The case of Southern Israel. Most studies conducted on the desert oasis effect have focused on the summer season, while the winter has received less attention. This study aimed to determine existence of the oasis climatic effect in winter season and investigate influence of d...

Furukawa, M.; Kawamoto, T.; Noshiro, M.; Honda, K.K.; Sakai, M.; Fujimoto, K.; Honma, S.; Honma, K.; Hamada, T.; Kato, Y., 2005: Clock gene expression in the submandibular glands. Clock genes, which mediate molecular circadian rhythms, are expressed in a circadian fashion in the suprachiasmatic nucleus and in various peripheral tissues. To establish a molecular basis for circadian regulation in the salivary glands, we exami...

Phinney, A.L.; Andringa, G.; Bol, J.G.J.M.; Wolters, E.Ch.; van Muiswinkel, F.L.; van Dam, A-Marie.W.; Drukarch, B., 2006: Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging. Rotenone has been reported to induce various degrees of Parkinsonism in rats. We tested whether advancing age alters the sensitivity of dopaminergic neurons to rotenone. A low, systemic dose of rotenone had no effect on young rats, but led to a 20...

Tay, K-Soon.Vincent.; Chong, S-Jack.; Tan, B-Keem., 2016: Impact of a Newly Implemented Burn Protocol on Surgically Managed Partial Thickness Burns at a Specialized Burns Center in Singapore. This study evaluated the impact of a newly implemented protocol for superficial to mid-dermal partial thickness burns which involves early surgery and rapid coverage with biosynthetic dressing in a specialized national burns center in Singapore. C...

Liu, S.; Ma, X.; Wang, B.; Shang, X.; Wang, W.; Yu, X., 2016: Investigation of the Effect of Thermal Annealing on Poly(3-hexylthiophene) Nanofibers by Scanning Probe Microscopy: From Single-Chain Conformation and Assembly Behavior to the Interfacial Interactions with Graphene Oxide. NlmCategory="UNASSIGNED">Poly(3-hexylthiophene) (P3HT) has been widely used in devices owing to its excellent properties and structural features. However, devices based on pure P3HT have not exhibited high performance. Strategies, suc...

Freud, A., 1950: Aggression in relation to normal and pathological emotional development. Revista de Psicoanalisis 7(3): 450-456

Mok, C.C.; Wong, R.W.; Lau, C.S., 1999: Lupus nephritis in Southern Chinese patients: clinicopathologic findings and long-term outcome. Despite the improvement in survival of patients with systemic lupus erythematosus (SLE) and associated nephritis in the past 20 years, few studies of the long-term outcome of large cohorts of patients with well-defined histological classes of lupu...