+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Indications for and survival after liver retransplantation

, : Indications for and survival after liver retransplantation. Transplantation Proceedings 42(2): 637-640

Orthotopic liver retransplantation (re-OLT) is the therapeutic option for hepatic graft failures. Survival after re-OLT is poorer than after primary OLT. Given that there is an organ shortage, it is essential that we optimize our use of this scarce resource. We evaluated the results of re-OLT among 58 consecutive Re-OLT. Using registry data from our Liver Transplantation Unit, we performed a retrospective cohort study of adult urgent versus elective re-OLT between 1991 and 2008. We recorded the indications for the initial OLT, and the intervals from OLT to re-OLT as well as age and gender. Using the Rosen model to stratify patients into low-intermediate-, and high-risk groups we calculated survivals. Among 661 adult liver transplantations, 56 patients (8.4%) underwent late re-OLT at a median of 654.4 days post-OLT. There were 17 (29%) urgent re-OLT and 41 elective cases (71%). Vascular complications were the most common cause of urgent re-OLT (64%); elective re-OLT was primarily due to chronic rejection (56.1%). Overall survival for retransplanted patients was significantly lower among urgent procedures (82.4% vs 48.8%), as well as for overall survival after re-OLT for patients with hepatitis C virus (HCV) versus other etiologies. These data confirmed the utility of retransplantation in elective and emergency situations. Liver re-transplantation has a high morbidity and mortality. It requires multidisciplinary experience to decide inclusion and prioritization criteria for re-OLT, especially among patients with HCV.


PMID: 20304211

DOI: 10.1016/j.transproceed.2010.02.017

Other references

Itabashi, H.M.tsukawa, T., 1979: Studies on nutritional signific. Kenkyu hokoku Bulletin: (59) 111-128

Mainali, L.; Raguz, M.; Subczynski, W.K., 2014: Formation of cholesterol bilayer domains precedes formation of cholesterol crystals in cholesterol/dimyristoylphosphatidylcholine membranes: EPR and DSC studies. Saturation-recovery EPR along with DSC were used to determine the cholesterol content at which pure cholesterol bilayer domains (CBDs) and cholesterol crystals begin to form in dimyristoylphosphatidylcholine (DMPC) membranes. To preserve compositi...

Wilkin P.J., 1990: The instantaneous force on a desert locust schistocerca gregaria orthoptera acrididae flying in a wind tunnel. A method is described using a strain gage probe to directly record the instantaneous vertical force and horizontal force on a locust in steady flight in a wind tunnel. The instantaneous forces contain both aerodynamic and wing inertial components....

Gusev, V.A.; Lomonosova, O.S.; Velichkovskii, B.T., 1997: Effect of chrysotile-asbestos and zeolite dust on generation of active oxygen species by alveolar macrophages and granulocytes. Different characteristics of the influence of dusts of chrysotile -asbestos, mordenite, erionite and klinoptilolite on the total generation of the active forms of oxygen by the alveolar macrophages and the generation of O-2- and H-2O-2 by the gran...

How-Martyn, E., 1931: Birth control information. Eugenics Review 22(4): 325-325

Senguptal, S.; Roy, A.; Mallick, M.Cuha.; Kundu, B.; Das, S.Kumar.; Das, S., 2002: F. N. A. C. of salivary glands. During a period of 12 years, 874 salivary gland lesions were aspirated of which 740 (86.85%) were from parotid gland. Cystic, inflammatory & neoplastic lesions were 25.25%. 54.45% & 20.30%, respectively. Plcomorphic adenoma was the commone...

Shen, Yuan; Chang, Chaur Fen, 1994: Quantitative analysis of photosynthetically active radiation and effective temperature with respect to dynamic growth of Chinese cabbage. Crop growth is significantly affected by the amount of incident photosynthetically active radiation (PAR) and temperature. A dynamic growth model was developed to estimate the influence of daily incident PAR and effective temperature on the relati...

Van Gaal, Luc, 2002: Visceral obesity is responsible for the health risks of obesity. International Journal of Obesity 26(Supplement 1): S174, August

Bondar, G., 1957: Novo genero e duas novas especies de Curculionideos (Coleoptera) de flores de moraceas. Revista Brasileira de Entomologia, 7: 257-261

Bowman B.H.; Carson S.D.; Mcneely M.C.; Lankford B.J.; Barnett D.R., 1976: Cystic fibrosis ciliary inhibitor distribution fractionation and properties. Federation Proceedings 35(7): 1563