+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Interventions for cognitive deficits in patients with a brain tumor: an update

, : Interventions for cognitive deficits in patients with a brain tumor: an update. Expert Review of Anticancer Therapy 10(11): 1779-1795

Patients with brain tumors may suffer from cognitive deficits caused by the disease and/or its treatment. Here, we review recent efforts in the research on prevention or treatment of cognitive deficits in these patients. We conclude that interest in this area is growing, but that methodological difficulties persist. In addition, we describe the recently completed first randomized controlled trial on the effectiveness of cognitive rehabilitation that we conducted in patients with brain cancer. By reflecting on the methodological challenges experienced in our trial, we hope to assist others in planning and conducting future studies on both pharmacological treatments and cognitive rehabilitation programs for cognitive deficits in this patient population. We conclude with suggestions for future research directions.


PMID: 21080804

DOI: 10.1586/era.10.163

Other references

Schirle, N.T.; Goodman, R.A.; Krishnamurthy, M.; Beal, P.A., 2011: Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide. RNA editing by adenosine deamination is a form of epigenetic control of gene expression wherein the ADAR enzymes convert adenosine to inosine in RNA often changing the meaning of codons. The pre-mRNA for the 2c subtype of serotonin receptor (5-HT2...

Antonelli P.; Nisperos B.; Nepom G.; Hansen J.; Choo S.Y., 1985: Electrophoretical variants of hla b 27 molecules from ankylosing spondylitis patients. Human Immunology 12(2): 121-122

Broussard, G.; Graham, S.L., 2001: Triangular wire. Journal of Clinical Orthodontics 35(1): 53-55

Till, A.R.; Blair, G.J., 1978: The utilization by grass of sulfur and phosphorus from clover litter. 35S and 32P were used to produce double-labeled clover (Trifolium repens) which was subsequently used as litter on carpet grass (Axonopus affinis) swards. The re-utilization of 35S and 32P was studied under 2 temperatures (15/10 and 28/

Hengstman, G.J.D.; van den Hoogen, F.H.J.; van Engelen, B.G.M., 2009: Treatment of the inflammatory myopathies: update and practical recommendations. The inflammatory myopathies are a heterogeneous group of diseases including dermatomyositis, polymyositis, and inclusion body myositis. Clinical trials in myositis are rare, making it difficult to make clear recommendations on the treatment of the...

Fritz Niggli H.; Schaeppi Buechi C., 1991: Adaptive response to dominant lethality of mature class a and immature class b oocytes of drosophila melanogaster to low doses of ionizing radiation effects in repair proficient yw and repair deficient strains mei 41d 5 and mus 302d 1. Mature oocytes (class A) and immature oocytes (class B) from a repair-proficient yw strain and two repair-deficient strains (mus 302D1 and mei 41D5) were initially X-irradiated with 0.02 Gy and subsequently treated at various time intervals with 2...

Kovács, G.L.; Borthaiser, Z.; Telegdy, G., 1985: Oxytocin reduces intravenous heroin self-administration in heroin-tolerant rats. Intravenous self-administration of heroin was studied in experimentally naive rats, as compared to this behavior in animals rendered tolerant to heroin by multiple injections. The tolerant rats also exhibited mild signs of spontaneous and naloxone...

Shanbhag, S.; Shanbhag, V., 2013: Clinical applications of cell-based approaches in alveolar bone augmentation: a systematic review. Cell-based approaches, utilizing adult mesenchymal stem cells (MSCs), are reported to overcome the limitations of conventional bone augmentation procedures.PurposeThe study aims to systematically review the available evidence on the characteristic...

Garcia Alfonso P.; Gomez Recio M.; Gonzalez Beca R.; Carrion Galindo R., 1985: Right atrial metastasis of osteosarcoma echocardiographic diagnosis. Revista Clinica Espanola 177(9): 453-455

Sato, S.; Ogihara, Y.; Hiraga, K.; Nishijima, A.; Hidano, A., 1977: Fine structure of unmyelinated nerves in neonatal skin. The fine structure of unmyelinated cutaneous nerve fibers in newborns was examined in lesions of adnexal polyp of neonatal skin. In the neonatal cutaneous nerves, unmyelinated fibers outnumbered myelinated ones. The unmyelinated fibers consisted o...