geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Investigation into the effect of varied functional biointerfaces on silicon nanowire MOSFETs


, : Investigation into the effect of varied functional biointerfaces on silicon nanowire MOSFETs. Sensors 12(12): 16867-16878

A biocompatible and functional interface can improve the sensitivity of bioelectronics. Here, 3-aminopropyl trimethoxysilane (APTMS) and 3-mercaptopropyl trimethoxysilane (MPTMS) self-assembled monolayers (SAMs) were independently modified on the surface of silicon nanowire metal-oxide-semiconductor field effect transistors (NW-MOSFETs). Those SAMs-modified silicon NW-MOSFETs were used to discriminate various pH solutions and further verify which modified regime was capable of providing better electrical signals. The APTMS-SAM modified NW-MOSFETs showed better electrical responses in pH sensing. Biomolecules on APTMS-SAM modified NW-MOSFETs also gave better signals for the corresponding proteind in physiological buffer solutions. Atomic force microscopy (AFM) clarified those electrical phenomena and found biomolecules on APTMS-SAM were relatively uniformly modified on NW-MOSFETs. Our results showed that more uniform modification contributed to better signal response to protein interactions in physiological buffer solutions. It suggests that suitable surface modifications could profoundly affect the sensing response and sensitivity.

US$19.90

PMID: 23223082

DOI: 10.3390/s121216867


Other references

Miyazato, M.; Yamashiro, S.; Goya, M.; Inafuku, H.; Ikehara, A.; Oshiro, Y.; Saito, S.; Kuniyoshi, Y., 2015: Early occlusion control of the intrapericardial inferior vena cava under femoral-femoral extracorporeal circulation using a technique to prevent pulmonary embolism during nephrectomy for renal cell carcinoma with tumor thrombus: two case reports. Renal cell carcinoma with tumor thrombus extension into the inferior vena cava occurs in approximately 5% of cases. Despite such situations, an aggressive surgical approach is recommended. However, intraoperative prevention of pulmonary embolism b...

Fulda, G.J.; Giberson, F.; Fagraeus, L., 2005: A prospective randomized trial of nebulized morphine compared with patient-controlled analgesia morphine in the management of acute thoracic pain. Background: Successfully managing pain for the trauma patient decreases morbidity, improves patient satisfaction, and is an essential component of critical care. Using patient-controlled analgesia (PCA) morphine to control pain may be complicated...

Groddeck G., 1977: The meaning of illness selected psychoanalytic writings. This volume is a collection of psychoanalytic writings by Georg Groddeck, selected, and with an introduction by Lore Schacht, and translated by Gertrud Mander. Writings included: Correspondence with Sigmund Frreud (1917-1934), Psychic Conditioning...

Lockwood, G.G., 1994: Techniques of mechanical ventilation in closed and low flow systems. Anaesthesia and Intensive Care 22(4): 419-425

McAndrew, L.M.; Markowitz, S.; Lu, S-En.; Borders, A.; Rothman, D.; Quigley, K.S., 2016: Resilience During War: Better Unit Cohesion and Reductions in Avoidant Coping Are Associated With Better Mental Health Function After Combat Deployment. The majority of individuals who endure traumatic events are resilient; however, we do not yet understand why some individuals are more resilient than others. We used data from a prospective longitudinal study Army National Guard and Reserve person...

Anonymous, 1997: Survey of equipment and supplies for seed testing. This directory lists equipment and supplies for seed testing from 283 companies world-wide.

Cuthbert, R.J., 1954: Löffler's syndrome occurring during streptomycin and P.A.S. therapy. British Medical Journal 2(4884): 398-399

Anthony Elizabeth Y.; Kappus Eric; Velador Jesus, 2002: Rio Grande Rift lithospheric structure and age as revealed by mantle xenoliths from Kilbourne Hole, New Mexico. There are two populations of spinel peridotite xenoliths at Kilbourne Hole: one that is more fertile, i.e. has higher modal clinopyroxene, and a population which is less fertile, with abundant modal olivine. The two groups show the appropriate att...

Bozhko, M.P., 1961: New genus and species of Aphidoidea (Homoptera) from southern Ukraina, Moldavia and Ciscaucasia. Trudy vsesoynzn ent Obshch Leningrad, 48: 5-37

Varol, C.; Vallon-Eberhard, A.; Elinav, E.; Aychek, T.; Shapira, Y.; Luche, Hé.; Fehling, H.Jörg.; Hardt, W-Dietrich.; Shakhar, G.; Jung, S., 2009: Intestinal lamina propria dendritic cell subsets have different origin and functions. The intestinal immune system discriminates between tolerance toward the commensal microflora and robust responses to pathogens. Maintenance of this critical balance is attributed to mucosal dendritic cells (DCs) residing in organized lymphoid tiss...