+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature

, : Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature. International Journal of Applied & Basic Medical Research 4(2): 128-130

Primary malignant lesions of the vagina are uncommon, and vaginal sarcomas are even rarer. We describe a rare case of stage I, high-grade leiomyosarcoma of the vagina treated with combined modality treatment. A 39-year-old female presented with vaginal mass and underwent resection. Histopathological examination revealed atypical leiomyoma of the vagina with definite risk of recurrence. Eleven months later, she presented with a recurrent vaginal mass and underwent exploratory laparotomy with total abdominal hysterectomy and bilateral salpingo-oophorectomy plus resection of recurrent tumor and partial vaginectomy. The detailed histopathological examination was suggestive of leiomyosarcoma of the vagina. The patient received adjuvant radiotherapy and chemotherapy. The patient is alive and disease-free 29 months postsurgery. Experience with vaginal leiomyosarcomas is limited. The optimal treatment methods have not yet been established because of the rarity of the tumor. We add another case of leiomyosarcoma of the vagina to the limited existing literature.


PMID: 25143892

DOI: 10.4103/2229-516X.136806

Other references

Wachtel, W.; Lyhs, L., 1969: Effect of continuous infusion of Escherichia coli endotoxins on the blood circulation of young pigs. Archiv für Experimentelle Veterinarmedizin 23(3): 633-642

Rocco, G.; de Chiara, A.Rosaria.; Fazioli, F.; Scognamiglio, F.; L.R.cca, A.; Apice, G.; Riva, C., 2009: Primary giant clear cell sarcoma (soft tissue malignant melanoma) of the sternum. One case of a primary clear cell sarcoma of the sternum (also called soft tissue melanoma) is reported. This neoplasm represents a rare occurrence, and as a rule, differential diagnosis with melanoma often requires detailed immunohistochemistry an...

Hammarstroem S., 1977: Prostaglandin formation and cyclic amp levels in cultured fibroblasts. Acta Pharmaceutica Suecica 14(SUPPL): 22

Krause, J.R.; Amores, R., 1976: Massive intraperitoneal hemorrhage from ruptured corpus luteum during anticoagulant therapy. The unpredictability of hemorrhagic complications during anticoagulant therapy is well known. An unusual case of massive intraperitoneal hemorrhage from a ruptured corpus luteum during such therapy is presented. That this complication is uncommon...

Anonymous, 1988: 11th International Congress on Animal Reproduction and Artificial Insemination, University College Dublin, Ireland, June 26-30 1988. Volume 5. Plenary and Symposia papers. Papers abstracted appear in the appropriate sections of ABA, and can be traced via the subject index, under the heading Conferences.

Chan, N.Shu-Wen.; Jap, A.; Chee, S-Phaik., 2016: Modified side-based scleral flap for intrascleral intraocular lens fixation. Journal of Cataract and Refractive Surgery 41(7): 1533-1535

Chang, C.Y.; Gill, C.M.; Huang, A.J.; Simeone, F.J.; Torriani, M.; McCarthy, J.C.; Bredella, M.A., 2016: Use of MR arthrography in detecting tears of the ligamentum teres with arthroscopic correlation. To demonstrate the normal appearance of the ligamentum teres on MR arthrography (MRA) and evaluate the accuracy of MRA in detecting ligamentum teres tears with arthroscopic correlation. Institutional Review Board approval was obtained with a waive...

Cheng, Z., 1995: Medicine in the 18th century. Zhonghua Yi Shi Za Zhi 25(1): 55-61

Anonymous, 2003: SSI benefits. Denial of SSI claim upheld for man who later qualified as disabled. Aids Policy & Law 18(6): 3-3

Chen-Woan, M.; McGregor, D.D.; Harris, W.V.; Greiner, D.L., 1986: Monoclonal antibody analysis of Listeria monocytogenes-induced cytotoxic lymphocytes. An immunizing infection with Listeria monocytogenes provides a potent stimulus for the formation of prekiller lymphocytes. Their cytolytic potential is revealed when the cells are restimulated in vitro by Listeria antigens. Listeria monocytogenes-...