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Geography & Life Sciences: Chapter 54110

Chapter 54110 provides bibliographic information on scholary research in geography and in the life sciences.



Lethal dose of stilbene derivatives in experimental animals. La Clinica Ostetrica E Ginecologica 52(3): 129-141

Lethal doses of oxbile, peptones and thiosulfate-citrate-bile-sucrose agar (TCBS) for Acanthaster planci; exploring alternative population control options. Marine Pollution Bulletin 75(1-2): 133-139

Lethal doses of ozone for control of all stages of internal and external feeders in stored products. Pest Management Science 68(9): 1311-1316

Lethal drug probe in China: the case of Xinfu clindamycin. Pharmacoepidemiology and Drug Safety 16(8): 928-932

Lethal effect and in vivo genotoxicity of profenofos to Chinese native amphibian (Rana spinosa) tadpoles. Archives of Environmental Contamination and Toxicology 59(3): 478-483

Lethal effect of CD3-specific antibody in mice deficient in TGF-beta1 by uncontrolled flu-like syndrome. Journal of Immunology 183(2): 953-961

Lethal effect of a hyperthermic CO₂ pneumoperitoneum on gastric cancer cells. Clinics and Research in Hepatology and Gastroenterology 38(4): 520-527

Lethal effect of adenovirus-mediated HSV-TK gene in combination with hydroxycamptothecin on human bladder cancer in vitro. Nan Fang Yi Ke Da Xue Xue Bao 27(4): 461-464

Lethal effect of chitosan-Ag (I) films on Staphylococcus aureus as evaluated by electron microscopy. Journal of Applied Microbiology 108(2): 633-646

Lethal effect of cytotoxic lymphocytes against U266 cells induced by DCs modified with GM-CSF gene and pulsed with tumour antigen. Zhongguo Shi Yan Xue Ye Xue Za Zhi 17(4): 929-932

Lethal effect of cytotoxin from Agkitrodon acutus venom on gastric cancer cells and their ultrastructure changes. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25(4): 335-337

Lethal effect of dehydroleucodine (DhL) on amphibian Bufo arenarum embryos. Food and Chemical Toxicology 50(3-4): 672-674

Lethal effect of electric fields on isolated ventricular myocytes. IEEE Transactions on Bio-Medical Engineering 55(11): 2635-2642

Lethal effects of Aspergillus niger against mosquitoes vector of filaria, malaria, and dengue: a liquid mycoadulticide. Thescientificworldjournal 2012: 603984-603984

Lethal effects of D.D.T. on young fish. Nature 158: 378-378

Lethal effects of Helianthemum lippii (L.) on Acanthamoeba castellanii cysts in vitro. Korean Journal of Parasitology 52(3): 243-249

Lethal effects of Trichoderma longibrachiatum on Heterodera avenae. Ying Yong Sheng Tai Xue Bao 25(7): 2093-2098

Lethal effects of a Mexican Beauveria bassiana (Balsamo) strain against Meccus pallidipennis (Stal). Brazilian Journal of Microbiology 45(2): 551-557

Lethal effects of abamectin on the aquatic organisms Daphnia similis, Chironomus xanthus and Danio rerio. Chemosphere 86(1): 36-40

Lethal effects of entomopathogenic nematodes on larvae of Dorysthenes hydropicus in laboratory experiment. Zhongguo Zhong Yao Za Zhi 35(10): 1239-1241

Lethal effects of heat and use of localized heat treatment for control of bed bug infestations. Journal of Economic Entomology 102(3): 1182-1188

Lethal effects of high-intensity violet 405-nm light on Saccharomyces cerevisiae, Candida albicans, and on dormant and germinating spores of Aspergillus niger. Fungal Biology 117(7-8): 519-527

Lethal effects of nanoliposome encapsulated cisplatin on Saos-2 cells and its distribution in nude mice bearing human. Beijing Da Xue Xue Bao. Yi Xue Ban 41(5): 525-530

Lethal effects of scopoletin and bisdemethoxycurcumin against Tetranychus cinnabarinus Boisd. (Acari: Tetranychidae): a simulation study. Ying Yong Sheng Tai Xue Bao 24(1): 197-204

Lethal encephalitis caused by the Toscana virus in an elderly patient. Journal of Neurology 259(1): 175-177

Lethal endometrial recurrence after cone biopsy for microinvasive cervical adenocarcinoma. Journal of Obstetrics and Gynaecology Research 34(3): 413-417

Lethal entanglement in baleen whales. Diseases of Aquatic Organisms 96(3): 175-185

Lethal enterovirus myocarditis associated with rituximab and chemotherapy for follicular lymphoma. Medicina Clinica 141(10): 459-460

Lethal epiphyseal stippling in the foetus and neonate; pathological implications. Virchows Archiv 456(3): 301-308

Lethal esophageal rupture following treatment with Sengstaken-Blakemore tube in management of variceal bleeding: a 10-year autopsy study. Forensic Science International 222(1-3): E19-E22

Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage. Applied Radiation and Isotopes 67(3): 454-459

Lethal evolution of a newborn with consistent features of hydrolethalus syndrome--Romanian patient. Genetic Counseling 22(3): 293-304

Lethal factor VII deficiency due to novel mutations in the F7 promoter: functional analysis reveals disruption of HNF4 binding site. Thrombosis and Haemostasis 108(2): 277-283

Lethal factor and anti-protective antigen IgG levels associated with inhalation anthrax, Minnesota, USA. Emerging Infectious Diseases 20(2): 310-314

Lethal factor toxemia and anti-protective antigen antibody activity in naturally acquired cutaneous anthrax. Journal of Infectious Diseases 204(9): 1321-1327

Lethal factor unfolding is the most force-dependent step of anthrax toxin translocation. Proceedings of the National Academy of Sciences of the United States of America 106(51): 21555-21560

Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge. American Journal of Pathology 184(12): 3205-3216

Lethal fecaloma. Journal of the American Geriatrics Society 55(6): 965-967

Lethal fetal anomalies: why the big void?. Obstetrics and Gynecology 119(4): 871; Author Reply 871-871; Author Reply 871

Lethal fighting in nematodes is dependent on developmental pathway: male-male fighting in the entomopathogenic nematode Steinernema longicaudum. Plos One 9(2): E89385-E89385

Lethal firearm-related violence against Canadian women: did tightening gun laws have an impact on women's health and safety?. Violence and Victims 28(5): 875-883

Lethal fish hook attachment - An unusual occurrence. Journal of Forensic and Legal Medicine 20(2): 117-118

Lethal forethought: delayed reward discounting differentiates high- and low-lethality suicide attempts in old age. Biological Psychiatry 70(2): 138-144

Lethal form of keratitis-ichthyosis-deafness syndrome caused by the GJB2 mutation p.Ser17Phe. Acta Dermato-Venereologica 94(5): 591-592

Lethal gallstone ileus. Forensic Science, Medicine, and Pathology 8(4): 473-474

Lethal gastric hemorrhage from a caliber-persistent artery of the antrum - a branch of the right gastric artery. Hippokratia 18(2): 172-176

Lethal generalized calcinosis and hypercalcemic crisis in primary hyperparathyroidism. Journal of Clinical Endocrinology and Metabolism 100(1): 17-18

Lethal genetic disorder in Poll Merino/Merino sheep in Australia. Australian Veterinary Journal 89(7): 254-259

Lethal giant cell arteritis with multiple ischemic strokes despite aggressive immunosuppressive therapy. Journal of the Neurological Sciences 295(1-2): 120-124

Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia. Plos One 9(1): E87376-E87376

Lethal giant larvae 2 regulates development of the ciliated organ Kupffer's vesicle. Development 140(7): 1550-1559

Lethal graft-versus-host disease in congenital neutropenia caused by p14 deficiency after allogeneic bone marrow transplantation from an HLA-identical sibling. Pediatric Blood & Cancer 51(3): 436-438

Lethal head entrapment--a problem characteristic of early childhood. Journal of Forensic and Legal Medicine 16(6): 340-342

Lethal hemorrhage caused by aortoesophageal fistula secondary to stent-graft repair of the thoracic aorta. Cardiovascular and Interventional Radiology 34 Suppl 2: S60-S63

Lethal hemorrhage from a ureteric-arterial-enteric fistula diagnosed by postmortem CT angiography. Forensic Science, Medicine, and Pathology 8(4): 430-435

Lethal hemothorax following thoracic dislocated spinal fracture: the usefulness of arterial embolization. International Journal of Emergency Medicine 2(3): 177-178

Lethal hepatic infarction following plasma exchange in living donor liver transplant patients. Transplant International 24(7): E57-E58

Lethal hepatocellular necrosis associated with herbal polypharmacy in a patient with chronic hepatitis B infection. Forensic Science International 241: 138-140

Lethal hereditary bullous epidermolysis; survey and a typical case. Acta Paediatrica 34(3): 263-278

Lethal herpesvirosis in 16 captive horned vipers (Vipera ammodytes ammodytes): pathological and ultrastructural findings. Journal of Comparative Pathology 150(2-3): 341-344

Lethal human herpesvirus-6 encephalitis after cord blood transplant. Transplant Infectious Disease 13(6): 646-649

Lethal human neutropenic entercolitis caused by Clostridium chauvoei in the United States: tip of the iceberg?. Journal of Infection 64(2): 225-227

Lethal hypoplasia and developmental anomalies of the lungs in a newborn with intrauterine adrenal hemorrhage and cerebral infarcts: a proposed pulmonary disruption sequence. Pediatric and Developmental Pathology 17(5): 374-381

Lethal hypothermia in South Australia. Medical Journal of Australia 197(11): 622-622

Lethal hypothermia in an animal model, not associated with basal renal epithelial vacuolization. Journal of Forensic and Legal Medicine 21: 14-16

Lethal hypothermia in dogs of various ages. Anesthesiology 7: 518-521

Lethal infection thresholds of Paenibacillus larvae for honeybee drone and worker larvae (Apis mellifera). Environmental Microbiology 12(10): 2838-2845

Lethal influenza B myocarditis in a child and review of the literature for pediatric age groups. Infection 38(3): 231-235

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes. Plos Pathogens 5(10): E1000604-E1000604

Lethal injection and physicians: state law vs medical ethics. JAMA 298(23): 2779-2781

Lethal injection as a component of a therapeutics toxicology module. American Journal of Pharmaceutical Education 75(6): 117-117

Lethal injection is not humane. Plos Medicine 4(4): E171-E171

Lethal injection of potassium chloride: first description of the pathological appearance of organs. Journal of Applied Toxicology 30(4): 378-380

Lethal injection: let's be honest about the death penalty. Plos Medicine 4(6): E213; Discussion E224-E213; Discussion E224

Lethal injections. Case for a doctor's involvement in judicial executions. Bmj 340: C2980-C2980

Lethal injections: legal extensions and implications of "do no harm". American Journal of Bioethics 8(10): 58-59

Lethal injections: medicine and research. Hastings Center Report 38(1): Following 52-Following 52

Lethal injuries following building collapse: comparison between autopsy and radiographic findings. La Radiologia Medica 116(6): 969-981

Lethal interaction: the colliding epidemics of tobacco and tuberculosis. Expert Review of Anti-Infective Therapy 5(3): 385-391

Lethal interactions among vertebrate top predators: a review of concepts, assumptions and terminology. Biological Reviews of the Cambridge Philosophical Society 89(2): 270-283

Lethal interactions between parasites and prey increase niche diversity in a tropical community. Science 343(6176): 1240-1244

Lethal intergroup aggression leads to territorial expansion in wild chimpanzees. Current Biology 20(12): R507-R508

Lethal intestinal perforation after foreign body ingestion in a superobese patient. Obesity Surgery 19(8): 1183-1185

Lethal intimate partner violence: an interactional perspective on women's perceptions of lethal incidents. Violence and Victims 28(5): 772-789

Lethal intoxication while driving a car. Archiv für Kriminologie 224(1-2): 10-16

Lethal intoxication with arsenic using prepared butter. Archiv für Kriminologie 221(5-6): 159-164

Lethal intravenous infusion of a wound antiseptic containing polyhexanide. Archiv für Kriminologie 223(3-4): 108-116

Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells. Leukemia & Lymphoma 52(11): 2169-2178

Lethal isotherms of cryoablation in a phantom study: effects of heat load, probe size, and number. Journal of Vascular and Interventional Radiology 20(10): 1343-1351

Lethal junctional epidermolysis bullosa with pyloric atresia due to compound heterozygosity for two novel mutations in the integrin β4 gene. Klinische Padiatrie 224(1): 8-11

Lethal lesions and amputation caused by plastic debris and fishing gear on the loggerhead turtle Caretta caretta (Linnaeus, 1758). Three case reports from Terceira Island, Azores (NE Atlantic). Marine Pollution Bulletin 86(1-2): 518-522

Lethal limb ischaemia in leukaemia. Case report and review of the literature. Journal of Thrombosis and Thrombolysis 28(3): 354-357

Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). Bmj Case Reports 2013: -

Lethal locations: an application of opportunity theory to motel suicide, a research note. Death Studies 32(8): 757-767

Lethal manifestations of systemic lupus erythematosus in a forensic context. Journal of Forensic Sciences 56(2): 423-428

Lethal mass mimicking myxoma in the heart. Asian Cardiovascular & Thoracic Annals 22(8): 962-964

Lethal means reduction: what have we learned?. Current Opinion in Pediatrics 21(5): 635-640

Lethal meningitis due to Pasteurella multocida. Medecine et Maladies Infectieuses 42(8): 374-375

Lethal metatropic dysplasia: a case report. Pathology 39(1): 177-181

Lethal methemoglobinemia and automobile exhaust inhalation. Forensic Science International 187(1-3): E1-E5

Lethal midline granuloma: a case of T-cell lymphoma. Wiener Klinische Wochenschrift 119(21-22): 625-625

Lethal migration: the bradykinin story. Journal of Physiology 592(22): 4805-4806

Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America 108(49): 19678-19682

Lethal monkeypox virus infection of CAST/EiJ mice is associated with a deficient gamma interferon response. Journal of Virology 86(17): 9105-9112

Lethal morphine intoxication in a patient with a sickle cell crisis and renal impairment: case report and a review of the literature. Human & Experimental Toxicology 30(9): 1399-1403

Lethal multiple pterygium syndrome associated with omphalocele. Genetic Counseling 18(4): 451-453

Lethal multiple sclerosis relapse after natalizumab withdrawal. Neurology 79(22): 2214-2216

Lethal mutagenesis and evolutionary epidemiology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 365(1548): 1953-1963

Lethal mutagenesis failure may augment viral adaptation. Molecular Biology and Evolution 31(1): 96-105

Lethal mutagenesis in a structured environment. Journal of Theoretical Biology 261(1): 67-73

Lethal mutagenesis in viruses and bacteria. Genetics 183(2): 639-650

Lethal mutagenesis of bacteria. Genetics 180(2): 1061-1070

Lethal mutagenesis of viruses. Current Opinion in Virology 1(5): 419-422

Lethal mutagenesis: targeting the mutator phenotype in cancer. Seminars in Cancer Biology 20(5): 353-359

Lethal mutants and truncated selection together solve a paradox of the origin of life. Plos One 6(7): E21904-E21904

Lethal mutations in the major homology region and their suppressors act by modulating the dimerization of the rous sarcoma virus capsid protein C-terminal domain. Proteins 81(2): 316-325

Lethal mutations produced by ultraviolet and X-ray irradiation of fungal spores. Australian Journal of Experimental Biology and Medical Science 26(Pt 3): 245-251

Lethal myocardial injury associated with hydrogen sulfide poisoning: report of two cases. Chudoku Kenkyu 24(3): 231-235

Lethal myocardial reperfusion injury: a necessary evil?. International Journal of Cardiology 151(1): 3-11

Lethal necrosis and perforation of the stomach and the aorta after multiple EUS-guided celiac plexus neurolysis procedures in a patient with chronic pancreatitis. Gastrointestinal Endoscopy 77(1): 151-152

Lethal necrotizing pneumonia caused by an ST398 Staphylococcus aureus strain. Emerging Infectious Diseases 17(6): 1152-3; Author Reply 1153

Lethal neonatal coagulopathy after maternal ingestion of a superwarfarin. Obstetrics and Gynecology 122(2 Pt 2): 500-502

Lethal nephrotropism of an H10N1 avian influenza virus stands out as an atypical pathotype. Veterinary Microbiology 173(3-4): 189-200

Lethal neuroendocrine carcinoma in ulcerative colitis. World Journal of Gastroenterology 15(46): 5882-5883

Lethal neuroleptic malignant syndrome due to amisulpride. Forensic Science, Medicine, and Pathology 9(2): 218-220

Lethal objection. Time 167(10): 50-51

Lethal obstructive colitis: how and when patients with colonic obstruction should be prevented from falling into a lethal condition. Hepato-Gastroenterology 56(91-92): 659-662

Lethal obstructive jaundice: a diagnosis not to be missed. British Journal of Hospital Medicine 71(11): 655-655

Lethal osteo-chondro-dysplasia: feto-pathological study of 32 cases. La Tunisie Medicale 87(2): 127-132

Lethal osteogenesis imperfecta-like condition with cutis laxa and arterial tortuosity in MZ twins due to a homozygous fibulin-4 mutation. Pediatric and Developmental Pathology 15(2): 137-141

Lethal outcome after intravenous administration of amiodarone in patient with atrial fibrillation and ventricular preexcitation. Journal of Cardiovascular Electrophysiology 22(9): 1077-1078

Lethal outcome after percutaneous aspiration of a presumed ovarian cyst in a neonate. Seminars in Pediatric Surgery 18(2): 119-121

Lethal outcome of 5-fluorouracil infusion in a patient with a total DPD deficiency and a double DPYD and UTG1A1 gene mutation. British Journal of Clinical Pharmacology 70(2): 280-283

Lethal outcome of post-tonsillectomy hemorrhage. European Archives of Oto-Rhino-Laryngology 265(12): 1527-1534

Lethal outcomes in Klippel-Trenaunay syndrome. Pediatric and Developmental Pathology 16(5): 337-342

Lethal outcomes: propofol infusion syndrome and propofol abuse. Clinical Nurse Specialist Cns 24(1): 8-10

Lethal pathogens, non-lethal synergists and the evolutionary ecology of resistance. Journal of Theoretical Biology 254(2): 339-349

Lethal pedestrian--passenger car collisions in Berlin. Changed injury patterns in two different time intervals. Legal Medicine 11 Suppl 1: S324-S326

Lethal perianal infection with septic shock: how should we manage this critical condition?. International Surgery 94(4): 292-297

Lethal phenotype of mice carrying a Sept11 null mutation. Biological Chemistry 392(8-9): 779-781

Lethal photosensitization of Porphyromonas gingivalis by their endogenous porphyrins under anaerobic conditions: an in vitro study. Photodiagnosis and Photodynamic Therapy 10(4): 677-682

Lethal pneumatosis coli in a 12-month-old child caused by acute intestinal gas gangrene after prolonged artificial nutrition: a case report. Journal of Medical Case Reports 2(): 238-238

Lethal pneumonitis after docetaxel chemotherapy: case report and review of the literature. Acta Oncologica 52(5): 1034-1038

Lethal poisoning with ethiofencarb and ethanol. Journal of Analytical Toxicology 33(7): 389-392

Lethal poisoning with the death-cap mushrooms. Sudebno-Meditsinskaia Ekspertiza 54(6): 23-26

Lethal poisonings with AH-7921 in combination with other substances. Forensic Science International 244: E21-E24

Lethal post-endoscopic retrograde cholangiopancreatography pancreatitis following fully covered metal stent placement in distal biliary obstruction due to unresectable cholangiocarcinoma. Digestive Endoscopy 25 Suppl 2: 117-121

Lethal presentation of neurofibromatosis and Noonan syndrome. American Journal of Medical Genetics. Part A 155a(6): 1360-1366

Lethal presentations of coronary artery spasm after an event-free period of six years following initial diagnosis. Journal of Invasive Cardiology 20(1): E30-E32

Lethal progressive thoracic insufficiency in a neonate due to jarcho levin syndrome. Journal of Clinical Neonatology 3(1): 49-50

Lethal protein in mass consumption edible mushroom Agrocybe aegerita linked to strong hepatic toxicity. Toxicon 90: 273-285

Lethal protein produced in response to competition between sibling bacterial colonies. Proceedings of the National Academy of Sciences of the United States of America 107(14): 6258-6263

Lethal pulmonary air embolism caused by the removal of a double-lumen hemodialysis catheter. American Journal of Forensic Medicine and Pathology 35(4): 237-238

Lethal pulmonary complications after pediatric allogeneic hematopoietic stem cell transplantation. Pediatric Infectious Disease Journal 31(2): 115-119

Lethal pulmonary embolisms are avoidable. Plastic and Reconstructive Surgery 123(2): 768; Author Reply 768-9

Lethal pulmonary hemorrhage caused by Stenotrophomonas maltophilia pneumonia in a patient with acute myeloid leukemia. Kansenshogaku Zasshi. Journal of the Japanese Association for Infectious Diseases 86(3): 300-305

Lethal pulmonary hypertension associated with ibuprofen treatment in a very low birth weight infant. Journal of Paediatrics and Child Health 50(1): 85-86

Lethal pulmonary infection with Francisella novicida causes depletion of alphabeta T cells from lungs. Cellular Immunology 257(1-2): 1-4

Lethal pulmonary infection with Francisella novicida is associated with severe sepsis. Journal of Leukocyte Biology 86(3): 491-504

Lethal pulmonary involvement of neutrophilic dermatosis following erythropoietin therapy. Annales de Dermatologie et de Venereologie 135(5): 384-388

Lethal pulmonary thromboembolism: an autopsy-based study on a rare but legally relevant event. Medicine, Science, and the Law 54(2): 78-83

Lethal reaction after contrast medium administration. Ugeskrift for Laeger 170(17): 1474-1474

Lethal recurrent pulmonary embolism. Ugeskrift for Laeger 174(16): 1098-1099

Lethal reperfusion injury in acute myocardial infarction: facts and unresolved issues. Cardiovascular Research 83(2): 165-168

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene. Journal of Clinical Endocrinology and Metabolism 94(1): 197-203

Lethal ricin intoxication in two adult dogs: toxicologic and histopathologic findings. Journal of Veterinary Diagnostic Investigation 22(3): 466-468

Lethal rupture of post-traumatic aneurysm of the vertebral artery case report. Journal of Forensic and Legal Medicine 16(3): 168-171

Lethal septic shock after dental scaling in a healthy dog due to Ochrobactrum anthropi-contaminated propofol. Journal of Small Animal Practice 56(5): 345-347

Lethal sex. Harefuah 150(3): 251-4, 303

Lethal sitting: homo sedentarius seeks answers. Physiology 29(5): 300-301

Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. New England Journal of Medicine 362(3): 206-216

Lethal small bowel necrosis due to aspergillosis during acute promyelocytic leukemia induction. American Journal of Hematology 88(4): 329-332

Lethal sphenoid fungal sinusitis in an immunocompromised elderly patient. B-Ent 5(3): 173-177

Lethal spontaneous aortic dissection in an adolescent. Journal of Forensic and Legal Medicine 16(5): 298-298

Lethal streptococcal outbreak in a long-term acute care hospital: what went wrong and why?. Clinical Infectious Diseases 52(8): 995-996

Lethal streptococcal toxic shock syndrome in pediatrics. Presentation of 3 cases. Medicina Intensiva 31(2): 100-103

Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses. Mbio 2(5): -

Lethal synergy involving bicyclomycin: an approach for reviving old antibiotics. Journal of Antimicrobial ChemoTherapy 69(12): 3227-3235

Lethal systemic air embolism in a multi-trauma patient. Journal of the American College of Surgeons 206(3): 591-591

Lethal systemic degos disease with prominent cardio-pulmonary involvement. Indian Journal of Dermatology 56(5): 564-567

Lethal temperature for pinewood nematode, Bursaphelenchus xylophilus, in infested wood using microwave energy. Journal of Nematology 42(2): 101-110

Lethal thermal impact at periphery of pyroclastic surges: evidences at Pompeii. Plos One 5(6): E11127-E11127

Lethal thyroid storm after uncontrolled intake of liothyronine in order to lose weight. International Journal of Legal Medicine 124(6): 637-640

Lethal toothpick. Mmw Fortschritte der Medizin 155(9): 31-31

Lethal toxin is a critical determinant of rapid mortality in rodent models of Clostridium sordellii endometritis. Anaerobe 16(2): 155-160

Lethal toxin of Clostridium sordellii is associated with fatal equine atypical myopathy. Veterinary Microbiology 144(3-4): 487-492

Lethal triad. Jems 39(6): 18-18

Lethal triad in severe burns. Burns 40(8): 1492-1496

Lethal troubles. Current Biology 19(7): R269-R270

Lethal varicella-zoster virus reactivation without skin lesions following renal transplantation. Nephrology, Dialysis, Transplantation 26(1): 365-368

Lethal vascular leak syndrome after denileukin diftitox administration to a patient with cutaneous gamma/delta T-cell lymphoma and occult cirrhosis. American Journal of Hematology 83(7): 593-595

Lethal visceral traumatic injuries secondary to child abuse: a case of practical application of autopsy, radiological and microscopic studies. Forensic Science International 206(1-3): E62-E66

Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy. Current Opinion in Cell Biology 22(2): 199-205

Lethal witness. Medico-Legal Journal 77(Pt 3): 93-105

Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A. Journal of Biological Chemistry 287(32): 26596-26605

Lethal, malignant, metastatic struma ovarii. Thyroid 20(9): 1037-1040

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3. Journal of Hepatology 53(1): 57-66

Lethal/severe osteogenesis imperfecta in a large family: a novel homozygous LEPRE1 mutation and bone histological findings. Pediatric and Developmental Pathology 14(3): 228-234

Lethality after gastroduodenal ulcer bleeding. Khirurgiia: 31-35

Lethality after surgical treatment of colorectal cancer. Positive effect of laparoscopy?. Der Chirurg; Zeitschrift für Alle Gebiete der Operativen Medizen 83(2): 179-180

Lethality and developmental delay in Drosophila melanogaster larvae after ingestion of selected Pseudomonas fluorescens strains. Plos One 5(9): E12504-E12504

Lethality and osteomuscular and cardiovascular complications in tetanus. Revista Brasileira de Terapia Intensiva 23(4): 434-441

Lethality and outcome in multiple injured patients after severe abdominal and pelvic trauma. Influence of preclinical volume replacement - an analysis of 604 patients from the trauma registry of the DGU. Der Unfallchirurg 114(8): 705-712

Lethality and pathogenesis of airborne infection with filoviruses in A129 α/β -/- interferon receptor-deficient mice. Journal of Medical Microbiology 61(Pt 1): 8-15

Lethality by pneumonia and factors associated to death. Jornal de Pediatria 90(1): 92-97

Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy. Plos One 7(1): E30527-E30527

Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1. Journal of Gene Medicine 10(10): 1083-1091

Lethality in gunshot chest wounds. Gospital'noe Delo: 36-43

Lethality of Alzheimer disease and its impact on nursing home placement. Alzheimer Disease and Associated Disorders 24(1): 90-95

Lethality of T-2 toxin, as applied by various methods, in adultAedes aegypti (Diptera: Culicidae) mosquitoes. Mycotoxin Research 4(1): 11-14

Lethality of atropine sulfate at high and low environmental temperature. Technical Report. Crdlr. Us Army Edgewood Arsenal Chemical Research and Development Laboratories 3108: 11-11

Lethality of cardiovascular events highlights the variable impact of complication type between thoracoscopic and open pulmonary lobectomies. Annals of Thoracic Surgery 97(3): 993-999

Lethality of cold immersion in rats. Federation Proceedings 7(1 Pt 1): 1-1

Lethality of endocarditis due to S. aureus among patients on hemodialysis. Nephrology Nursing Journal 36(6): 613-9, 632

Lethality of home-style dehydrator processes against Escherichia coli O157:H7 and salmonella serovars in the manufacture of ground-and-formed beef jerky and the potential for using a pathogen surrogate in process validation. Journal of Food Protection 72(10): 2056-2064

Lethality of reduced-risk insecticides against plum curculio (Coleoptera: Curculionidae) in blueberries, with emphasis on their curative activity. Pest Management Science 69(12): 1334-1345

Lethality of sortase depletion in Actinomyces oris caused by excessive membrane accumulation of a surface glycoprotein. Molecular Microbiology 94(6): 1227-1241

Lethality of suicide methods. Injury Prevention 14(1): 39-45

Lethality of taurine and alcohol coadministration in mice. Advances in Experimental Medicine and Biology 776: 29-38

Lethality rate of hematemesis and melena treated non-operatively (Meulengracht's regimen) and criteria for surgical intervention in bleeding peptic ulcer. Gastroenterology 12(4): 597-616

Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species . Leukemia Research 32(10): 1546-1553

Lethality toxicities induced by metal exposure during development in nematode Caenorhabditis elegans. Bulletin of Environmental Contamination and Toxicology 83(4): 530-536

Lethality, accumulation and toxicokinetics of aluminum in some tissues of male albino rats. Toxicology and Industrial Health 29(3): 254-263

Lethargic Encephalitis. California State Journal of Medicine 17(5): 136-137

Lethargic Encephalitis: The Glasgow Epidemic of 1923: Its Incidence and Consequences, from the Point of View of Public Health. Journal of Hygiene 31(2): 162-188

Lethargic encephalitis. Report of one case. Revista Medica de Chile 141(4): 531-534

Lethargica Medicalis. Journal of the National Medical Association 17(2): 71-72

Lethargy in a 9-year-old girl. A good history goes a long way. Advance for Nurse Practitioners 16(9): 22-23

Lethargy, fever, and anorexia in a thoroughbred weanling. Compendium 34(4): E1-E1

Letheon: the cadenced story of anesthesia. Science 199(4331): 857-860

Lethrus (Lethrus) schneideri sp. n. (Coleoptera, Geotrupidae) from Greece. Zookeys: 93-106

Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. Proceedings of the National Academy of Sciences of the United States of America 110(24): E2249-E2254

Letrozole. Expert Opinion on Drug Metabolism & Toxicology 6(2): 251-259

Letrozole Potentiates Mitochondrial and Dendritic Spine Impairments Induced by β Amyloid. Journal of Aging Research 2013: 538979-538979

Letrozole administration during the luteal phase after ovarian stimulation impacts corpus luteum function: a randomized, placebo-controlled trial. Fertility and Sterility 92(1): 222-225

Letrozole and desogestrel-only contraceptive pill for the treatment of stage IV endometriosis. Australian & New Zealand Journal of Obstetrics & Gynaecology 47(3): 222-225

Letrozole and gonadotropins versus luteal estradiol and GnRH-antagonist protocol: additional concerns. Fertility and Sterility 95(8): E78; Author Reply E80-E78; Author Reply E80

Letrozole and gonadotropins versus luteal estradiol and gonadotropin-releasing hormone antagonist protocol in women with a prior low response to ovarian stimulation. Fertility and Sterility 95(7): 2330-2334

Letrozole and norethisterone acetate in colorectal endometriosis. European Journal of Obstetrics, Gynecology, and Reproductive Biology 150(2): 199-202

Letrozole as a booster therapy in growth hormone deficiency. Indian Pediatrics 46(7): 625-627

Letrozole as adjuvant therapy for postmenopausal women with early breast cancer. Managed Care Interface 20(9): 30-1, 36

Letrozole as primary therapy for endometrial hyperplasia in young women. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics 100(1): 10-12

Letrozole as upfront endocrine therapy for postmenopausal women with hormone-sensitive breast cancer: BIG 1-98. Breast Cancer Research and Treatment 105 Suppl 1: 55-66

Letrozole co-treatment in infertile women 40 years old and older receiving controlled ovarian stimulation and intrauterine insemination. Fertility and Sterility 91(6): 2501-2507

Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer. Breast Cancer Research and Treatment 141(1): 119-123

Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. Human Reproduction 24(12): 3033-3041

Letrozole compared with tamoxifen as initial adjuvant therapy for breast cancer. Journal of Clinical Oncology 25(15): 2147-8; Author Reply 2148

Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: the BIG 1-98 trial. Journal of Clinical Oncology 26(12): 1972-1979

Letrozole dispersed on poly (vinyl alcohol) anchored maleic anhydride grafted low density polyethylene: a controlled drug delivery system for treatment of breast cancer. Colloids and Surfaces. B, Biointerfaces 116: 169-175

Letrozole effective in ovarian cancer. Lancet. Oncology 8(8): 678-678

Letrozole efficacy in the treatment of granulosa cell tumor of the ovary: a case report. Onkologie 36(9): 498-500

Letrozole for ovulation induction and controlled ovarian hyperstimulation. Current Opinion in Obstetrics & Gynecology 22(4): 289-294

Letrozole in a low-cost in vitro fertilization protocol in intracytoplasmic sperm injection cycles for male factor infertility: A randomized controlled trial. Journal of Human Reproductive Sciences 5(2): 170-174

Letrozole in ovulation induction: time to make decisions. Human Reproduction Update 15(2): 263-264

Letrozole in the extended adjuvant setting: MA.17. Breast Cancer Research and Treatment 105 Suppl 1: 45-53

Letrozole in the neoadjuvant setting: the P024 trial. Breast Cancer Research and Treatment 105 Suppl 1: 33-43

Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary. Fertility and Sterility 99(3): 889-896

Letrozole induced hypercalcemia in a patient with breast cancer. Case Reports in Oncological Medicine 2014: 608585-608585

Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin. Gynecological Endocrinology 27(4): 209-215

Letrozole inhibits the osteogenesis of medullary bone in prelay pullets. Poultry Science 89(5): 917-923

Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels. Clinical Cancer Research 14(19): 6330-6335

Letrozole monotherapy in the treatment of uterine myomas. Fertility and Sterility 93(7): E31; Author Reply E32-E31; Author Reply E32

Letrozole ovulation induction: an effective option in endometrial preparation for frozen-thawed embryo transfer. Archives of Gynecology and Obstetrics 289(3): 687-693

Letrozole plus GnRH analogue as preoperative and adjuvant therapy in premenopausal women with ER positive locally advanced breast cancer. Breast Cancer Research and Treatment 126(2): 431-441

Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix. Fertility and Sterility 91(5 Suppl): 2172-2176

Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer. Journal of Clinical Oncology 26(10): 1671-1676

Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer. New England Journal of Medicine 361(8): 766-776

Letrozole versus Clomiphene Citrate for Induction of Ovulation in Patients with Polycystic Ovarian Syndrome Undergoing Intrauterine Insemination. Clinical Medicine Insights. Reproductive Health 5(): 11-16

Letrozole versus clomiphene citrate for unexplained infertility: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology Research 40(5): 1205-1216

Letrozole versus clomiphene citrate: which is better for ovulation induction?. Fertility and Sterility 92(3): 858-859

Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. New England Journal of Medicine 371(2): 119-129

Letrozole versus combined metformin and clomiphene citrate for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial. Fertility and Sterility 94(4): 1405-1409

Letrozole versus laparoscopic ovarian diathermy for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized controlled trial. Archives of Gynecology and Obstetrics 282(5): 567-571

Letrozole versus letrozole plus Lapatinib (GW572016) in hormone-sensitive, HER2-negative operable breast cancer: a double-blind, randomized, phase II study with biomarker evaluation (EGF109077-LAP107692/LETLOB). Clinical Breast Cancer 8(1): 97-100

Letrozole versus testosterone. a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels. Journal of Sexual Medicine 4(2): 502-508

Letrozole vs anastrozole for height augmentation in short pubertal males: first year data. Journal of Clinical Endocrinology and Metabolism 99(11): 4086-4093

Letrozole vs. tamoxifen as neoadjuvant therapy for postmenopausal patients with hormone-dependent locally-advanced breast cancer. Ginecologia Y Obstetricia de Mexico 79(9): 553-557

Letrozole withdrawal response in locally advanced breast cancer. Annals of Oncology 22(8): 1927-1928

Letrozole, berberine, or their combination for anovulatory infertility in women with polycystic ovary syndrome: study design of a double-blind randomised controlled trial. Bmj Open 3(11): E003934-E003934

Letrozole: a review of its use in the treatment of postmenopausal women with hormone-responsive early breast cancer. Drugs 69(12): 1681-1705

Letrozole: a well-tolerated and effective treatment for breast cancer. Women's Health 2(5): 673-685

Letrozole: advancing hormone therapy in breast cancer. Women's Health 8(6): 611-618

Letrozole: present and future role in the treatment of breast cancer. Expert Opinion on PharmacoTherapy 8(12): 1965-1975

Lets Do Lunch? The ethics of accepting gifts from the pharmaceutical industry. Canadian Nurse 104(4): 30-35

Lets be frank. Revue de Medecine Navale ; Travaux Scientifiques des Medecins et Pharmaciens-Chimistes de la Marine 13(1-2): 177-178

Lets build a network of engaged, informed physicians to achieve our goals. Iowa Medicine 98(3): 8-8

Lets go ahead?. Cadernos de Saude Publica 29(9): 1727-1730

Lets innovate: new center aims to accelerate information exchange. Hospitals & Health Networks 87(11): 24-24

Lets talk about sex. British Journal of Nursing 17(20): 1260-1260

Lets talk. Making time for a 'sacred moment'. Hospitals & Health Networks 88(7): 22, 24-22, 24

Letter. Conservation Biology 3(4): 332-333

Letter. Academic Psychiatry 17(4): 208-208

Letter. Pathology Oncology Research 3(4): 326-327

Letter. Klinische Monatsblatter für Augenheilkunde 230(10): 1044-1045

Letter. Klinische Monatsblatter für Augenheilkunde 230(11): 1154-1155

Letter. Spine 39(5): 454-454

Letter - Re: Primary carotid stenting without angioplasty. Interventional Neuroradiology 14(4): 473-473

Letter Concerning the Late Howard Morrow, M. D. California and Western Medicine 55(6): 334-334

Letter From Colonel W. Preston Corderman To J. Mckeen Cattell, July 21, 1942. Science 96(2488): 221-221

Letter From Colonel W. Preston Corderman To J. Mckeen Cattell, June 30, 1942. Science 96(2488): 217-218

Letter From Douglas Cockerell, Letchworth, England, October 1, To His Brother In Colorado. Science 94(2452): 610-610

Letter From Great Britain. American Journal of Public Health and the Nation's Health 22(2): 185-187

Letter From J. Mckeen Cattell To Major N. V. Carlson, July 17, 1942. Science 96(2488): 220-221

Letter From J. Mckeen Cattell To Professor Luther P. Eisenhart, National Research Council, June 25, 1942. Science 96(2488): 216-217

Letter From J. Mckeen Cattell, Editor Of Science, To Colonel W. Preston Corderman, Chief Postal Censor, Written From Lancaster, Pennsylvania, June 27, 1942. Science 96(2488): 216-216

Letter From Major N. V. Carlson To J. Mckeen Cattell, July 14, 1942. Science 96(2488): 219-219

Letter From Major N. V. Carlson, Acting Chief Postal Censor, To J. Mckeen Cattell, July 14, 1942. Science 96(2488): 219-219

Letter From Paracelsus to Erasmus. Provincial Medical Journal and Retrospect of the Medical Sciences 7(164): 142-142

Letter From Professor Ed. Claparede. Science 41(1058): 534-534

Letter From The Secretaries Of The Royal Society. Science 1(7): 182-184

Letter From Vienna. Canadian Medical Association Journal 17(9): 1081-1081

Letter From the Chair (ACCWS). Journal of the American College of Certified Wound Specialists 1(3): 77-77

Letter From the Editors: The same high standards-A whole new approach. Western Journal of Medicine 170(4): 197-197

Letter From the Guest Editor: New exciting advances in the field of focal adhesion dynamics. Cell Adhesion & Migration 3(2): 177-178

Letter Of Appreciation From Medical Women's National Association. California State Journal of Medicine 21(8): 356-356

Letter Of October 6 And Its Enclosure. California and Western Medicine 33(5): 820-820

Letter Of The Local Committee Of The Scientific Societies. Science 2(50): 801-801

Letter On The Smithsonian Institution. Science 49(1265): 300-301

Letter RE: Derivation of a drinking water equivalent level (DWEL) related to the maximum contaminant level goal for perfluorooctanoic acid (PFOA), a persistent water soluble compound. Food and Chemical Toxicology 48(7): 1994-5; Author Reply 1996-7

Letter Re: Feder et al article. Clinical Infectious Diseases 54(6): 886-7; Author Reply 888-9

Letter Re: Gallbladder cancer involving the extrahepatic bile duct is worthy of resection. Annals of Surgery 258(1): E10-E11

Letter Re: Winter 2008 Editorial, "Plantar Fasciitis: What's An Evidence-Informed Consumer To Do?". PhysioTherapy Canada. Physiotherapie Canada 60(4): 380-381

Letter Re: "Operative outcomes beyond 30-day mortality: colorectal cancer surgery in oldest old" no reply. Annals of Surgery 258(1): E13-E13

Letter Regarding: Piegorsch, W.W., Cutter, S.L., and Hardisty, F. (2007). Benchmark analysis for quantifying urban vulnerability to terrorist incidents. Risk Analysis, 27(6), 1411-1425. Risk Analysis 29(9): 1199-200; Author Reply 1201-2

Letter To The Secretary Of Agriculture Dismissing The Charges Against Officers Of The Bureau Of Chemistry. Science 34(873): 367-371

Letter about Invisalign practices--important!. Journal - Oklahoma Dental Association 103(1): 26-26

Letter about editorial. Praxis 102(5): 252-252

Letter addressed to the Earl of Devon on Labourers' Sick Clubs. Provincial Medical Journal and Retrospect of the Medical Sciences 4(83): 77-78

Letter and letter-string processing in developmental dyslexia. Cortex; A Journal Devoted to the Study of the Nervous System and Behavior 46(10): 1272-1283

Letter by Abdellaoui et al regarding article, "Intracoronary compared with intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention". Circulation 119(3): E19; Author Reply E20-E19; Author Reply E20

Letter by Abdul-Khaliq et al regarding article, "Right ventricular mechanics and QRS duration in patients with repaired tetralogy of Fallot: implications of infundibular disease". Circulation 117(13): E300; Author Reply E301-E300; Author Reply E301

Letter by Abergel and Chauvel regarding article, “Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival". Circulation 130(5): E38-E38

Letter by Aboyans et al regarding article, "Smoking, clopidogrel, and mortality in patients with established cardiovascular disease". Circulation 122(3): E394; Author Reply E395-E394; Author Reply E395

Letter by Agostini et al regarding article, "Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern". Circulation 116(16): E388; Author Reply E390-E388; Author Reply E390

Letter by Ahluwalia and Hobbs regarding article, "Nitrate-nitrite-nitric oxide pathway in pulmonary arterial hypertension therapeutics". Circulation 127(2): E275-E275

Letter by Ahmed regarding article, "Second internal thoracic artery versus radial artery in coronary artery bypass grafting: a long-term, propensity score-matched follow-up study". Circulation 125(17): E629; Author Reply E631-E629; Author Reply E631

Letter by Ainslie et al regarding article, "Endogenous circadian rhythm in vasovagal response to head-up tilt". Circulation 124(13): E358; Author Reply E359-E358; Author Reply E359

Letter by Akar et al regarding article, "Effect of autologous bone-marrow cell transplantation on ischemic ulcer in patients with Buerger's disease". Circulation Journal 72(4): 684; Author Reply 685-6

Letter by Al-Ruzzeh and Navia regarding article, "Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery". Circulation 121(9): E234-E234

Letter by Ala-Korpela et al regarding article, "Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women". Circulation 120(17): E149; Author Reply E150-E149; Author Reply E150

Letter by Albertal and Belardi regarding article, "Cardiac Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study: a prospective, randomized control trial". Circulation 120(14): E131; Author Reply E133-E131; Author Reply E133

Letter by Albertal et al regarding article "Interventional therapy of bifurcation lesions: a TIMI flow-guided concept to treat side branches in bifurcation lesions--a prospective randomized clinical study (Thueringer bifurcation study, THUEBIS study as pilot trial)". Circulation. Cardiovascular Interventions 3(2): E2; Author Reply E3-E2; Author Reply E3

Letter by Albin regarding article, "Local brain temperature reduction via intranasal cooling with the RhinoChill device: preliminary safety data in brain-injured patients". Stroke 43(1): E6; Author Reply E7-E6; Author Reply E7

Letter by Aleryani and Al-Akwa regarding article, "Acute coronary syndrome and khat herbal amphetamine use: an observational report". Circulation 126(6): E85; Author Reply E87-8

Letter by Alexopoulos et al regarding article, "pharmacodynamic effect of switching therapy in patients with high on-treatment platelet reactivity and genotype variation with high clopidogrel dose versus prasugrel: the RESET GENE Trial". Circulation. Cardiovascular Interventions 6(1): E11-E11

Letter by Alfonso et al regarding article, "Impact of intravascular ultrasound guidance on long-term mortality in stenting for unprotected left main coronary artery stenosis". Circulation. Cardiovascular Interventions 2(5): E3; Author Reply E4-E3; Author Reply E4

Letter by Alfonso et al regarding article, "Paclitaxel-coated balloon catheter versus paclitaxel-coated stent for the treatment of coronary in-stent restenosis". Circulation 121(6): E33; Author Reply E34-5

Letter by Alla et al regarding article, "Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study". Circulation 124(21): E553; Author Reply E555-E553; Author Reply E555

Letter by Alter and Rupp regarding article, "OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction". Circulation 124(1): E23; Author Reply E24-5

Letter by Alter regarding article, "Myocardial fibrosis as a key determinant of left ventricular remodeling in idiopathic dilated cardiomyopathy: a contrast-enhanced cardiovascular magnetic study". Circulation. Cardiovascular Imaging 6(6): E77-E77

Letter by Altman and Gonzalez regarding article, "Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study". Circulation 124(21): E554; Author Reply E555-E554; Author Reply E555

Letter by Alvarez regarding article, "Coronary artery spasm: a 2009 update". Circulation 123(13): E396; Author Reply E397-E396; Author Reply E397

Letter by Ammirati and Maseri regarding article, "Bacterial signatures in thrombus aspirates of patients with myocardial infarction". Circulation 128(15): E235-E235

Letter by Ando et al regarding article, "Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy". Circulation 119(22): E557; Author Reply E558-E557; Author Reply E558

Letter by Andreassi regarding article, "systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies". Circulation 127(9): E475-E475

Letter by Andreoletti et al regarding article, "contribution and risks of left ventricular endomyocardial biopsy in patients with cardiomyopathies: a retrospective study over a 28-year period". Circulation 130(4): E30-E30

Letter by Andò et al regarding article, "Risk of acute kidney injury after percutaneous coronary interventions using radial versus femoral vascular access: insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium". Circulation. Cardiovascular Interventions 7(3): 419-419

Letter by Angelini et al regarding article, "incidence of sudden cardiac death in the national collegiate athletic association". Circulation 124(18): E485; Author's Reply E486-E485; Author's Reply E486

Letter by Angelini regarding article, "long-term outcome and impact of surgery on adults with coronary arteries originating from the opposite coronary cusp". Circulation 124(14): E383-E383

Letter by Antonelli Incalzi et al regarding article, "endogenous erythropoietin and outcome in heart failure". Circulation 122(10): E449; Author Reply E450-E449; Author Reply E450

Letter by Antoniades et al regarding article, "Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction". Circulation 122(21): E558; Author Reply E559-E558; Author Reply E559

Letter by Antonopoulos et al regarding article, "Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes". Stroke 42(6): E399-400; Author Reply E401

Letter by Anusionwu regarding article, "Left ventricular diastolic function is associated with symptom status in severe aortic valve stenosis" . Circulation. Cardiovascular Imaging 7(2): 412-412

Letter by Anyfanti et al regarding article, "Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study". Circulation 124(20): E536; Author Reply E537-E536; Author Reply E537

Letter by Apostolakis et al regarding article, "renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R2CHADS2 index in the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study cohorts". Circulation 128(11): E171-E171

Letter by Aquaro et al regarding article, "intermediate-signal-intensity late gadolinium enhancement predicts ventricular tachyarrhythmias in patients with hypertrophic cardiomyopathy". Circulation. Cardiovascular Imaging 5(3): E38-E38

Letter by Argulian and Messerli regarding article, "effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) trial". Circulation 130(3): E18-E18

Letter by Aries et al Regarding Article, "Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head-of-Bed Manipulation". Stroke 45(9): E189-E189

Letter by Aries et al regarding article, "Systolic blood pressure after intravenous antihypertensive treatment and clinical outcomes in hyperacute intracerebral hemorrhage: the Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study". Stroke 44(11): E152-E152

Letter by Aries et al regarding article, "autoregulation of cerebral blood flow is preserved in primary intracerebral hemorrhage". Stroke 44(9): E114-E114

Letter by Arrich et al regarding article, "Bystander-initiated rescue breathing for out-of-hospital cardiac arrests of noncardiac origin". Circulation 123(7): E249; Author Reply E250-E249; Author Reply E250

Letter by Arsava and Topcuoglu regarding article, "Ischemic brain injury following intracerebral hemorrhage--a critical review". Stroke 43(12): E174; Author Reply E175-E174; Author Reply E175

Letter by Ashrani regarding article, "Birth weight is a significant risk factor for incident atrial fibrillation". Circulation 123(14): E406; Author Reply E407-E406; Author Reply E407

Letter by Assenza et al regarding article, "Electrocardiographic features of arrhythmogenic right ventricular dysplasia". Circulation 121(19): E405; Author Reply E406-E405; Author Reply E406

Letter by Attaran regarding article, "Cardiac Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study: a prospective, randomized control trial". Circulation 120(14): E132; Author Reply E133-E132; Author Reply E133

Letter by Augoustides regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients". Circulation 117(22): E474; Author Reply E476-E474; Author Reply E476

Letter by Augoustides regarding article, "Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery". Circulation 117(25): E506; Author Reply E507-E506; Author Reply E507

Letter by Augoustides regarding article, "Risk index for perioperative renal dysfunction/failure: critical dependence on pulse pressure hypertension". Circulation 116(5): E119; Author Reply E120-E119; Author Reply E120

Letter by Ayalloore and LeLorier regarding article, "Relationship between nonsustained ventricular tachycardia after non-ST-elevation acute coronary syndrome and sudden cardiac death: observations from the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial". Circulation 123(14): E404; Author Reply E405-E404; Author Reply E405

Letter by Azoulay and Suissa regarding article, "statins and the risk of cancer after heart transplantation". Circulation 127(5): E439-E439

Letter by Bachhuber and Lott regarding article, "Characteristics of children hospitalized with infective endocarditis". Circulation 120(12): E94; Author Reply E95-E94; Author Reply E95

Letter by Baker et al regarding article, "benefits and risks of corticosteroid prophylaxis in adult cardiac surgery: a dose-response meta-analysis". Circulation 120(20): E163-E163

Letter by Ballo et al regarding article, "Serial biomarker measurements in ambulatory patients with chronic heart failure: the importance of change over time". Circulation 117(4): E23; Author Reply E24-E23; Author Reply E24

Letter by Banach et al regarding article, "postoperative treatment with carvedilol, a beta-adrenergic blocker, prevents paroxysmal atrial fibrillation after coronary artery bypass grafting". Circulation Journal 72(8): 1388; Author Reply 1389-1388; Author Reply 1389

Letter by Bandera et al regarding article, "Value of peak exercise oxygen consumption combined with B-type natriuretic peptide levels for optimal timing of cardiac transplantation". Circulation. Heart Failure 6(3): E41-E41

Letter by Banker et al regarding article, "cardiac resynchronization therapy in patients with heart failure and a QRS complex <120 milliseconds: the Evaluation of Resynchronization Therapy for Heart Failure (LESSER-EARTH) trial". Circulation 128(14): E216-E216

Letter by Barison et al regarding article, "Cardiac magnetic resonance postcontrast T1 time is associated with outcome in patients with heart failure and preserved ejection fraction". Circulation. Cardiovascular Imaging 7(2): 414-414

Letter by Barlis et al regarding article, "Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesions: results from a real-world multicenter registry. Circulation 118(18): E679; Author Reply E681-E679; Author Reply E681

Letter by Barra and Agarwal regarding article, "Survival after implantable cardioverter-defibrillator implantation in the elderly". Circulation 129(6): E336-E336

Letter by Barrios et al regarding article, "Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study". Circulation 120(18): E153; Author Reply E154-E153; Author Reply E154

Letter by Barrios et al regarding article, "Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women". Circulation 121(5): E29-E29

Letter by Baruteau et al regarding article, "Peripartum cardiomyopathy as a part of familial dilated cardiomyopathy". Circulation 123(2): E8; Author Reply E9-E8; Author Reply E9

Letter by Bastiaenen and Behr regarding article, "Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcome". Circulation 124(24): E899; Author Reply E900-E899; Author Reply E900

Letter by Bath regarding article, "A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes". Stroke 43(8): E71; Author Reply E72-E71; Author Reply E72

Letter by Begg et al regarding article, "The effects of vitamin d supplementation on physical function and quality of life in older heart failure patients: a randomized controlled trial". Circulation. Heart Failure 3(4): E24; Author Reply E25-E24; Author Reply E25

Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias". Circulation 118(21): E701; Author Reply E702-E701; Author Reply E702

Letter by Bell and O'keefe regarding article, "Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease". Circulation 118(11): E156; Author Reply E157-E156; Author Reply E157

Letter by Bellomo et al regarding article, "Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest". Circulation 125(3): E288; Author Reply E289-E288; Author Reply E289

Letter by Benbir et al regarding article, "The cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy scale. A screening tool to select patients for NOTCH3 gene analysis". Stroke 44(3): E18-E18

Letter by Benedetto et al regarding article, "Importance of refractory pain and hypertension in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD)". Circulation 123(24): E636-E636

Letter by Benedict et al regarding article, "What causes disability after transient ischemic attack and minor stroke? Results from the CT and MRI in the Triage of TIA and minor cerebrovascular events to identify high-risk patients (CATCH) study". Stroke 44(4): E32-E32

Letter by Beniwal and Bhaya regarding article, "Rheumatic heart disease screening by echocardiography: The inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease". Circulation 121(21): E422; Author Reply E423-E422; Author Reply E423

Letter by Berenfeld and Jalife regarding article "dominant frequency of atrial fibrillation correlates poorly with atrial fibrillation cycle length". Circulation. Arrhythmia and Electrophysiology 3(1): E1; Author Reply E2-3

Letter by Berger et al. regarding article, "Cardiac memory in patients with Wolff-Parkinson-White syndrome: noninvasive imaging of activation and repolarization before and after catheter ablation". Circulation 119(7): E209; Author Reply E210-E209; Author Reply E210

Letter by Bernstein et al regarding article, "reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 125(16): E614; Author Reply E616-E614; Author Reply E616

Letter by Berruezo et al regarding article, "Impact of local ablation on interconnected channels within ventricular scar: mechanistic implications for substrate modification". Circulation. Arrhythmia and Electrophysiology 7(2): 362-362

Letter by Bertoletti et al regarding article, "Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA)". Circulation 130(12): E108-E108

Letter by Bestetti and Cardinalli-Neto regarding article, "Ten-year incidence of Chagas cardiomyopathy among asymptomatic, Trypanosoma cruzi-seropositive former blood donors". Circulation 128(9): E136-E136

Letter by Bhindi and Ormerod regarding article, "Aortic arch plaques and risk of recurrent stroke and death". Circulation 121(2): E10; Author Reply E12-E10; Author Reply E12

Letter by Bhindi and Ormerod regarding article, "Lack of association between migraine headache and patent foramen ovale: results of a case-control study". Circulation 122(24): E581; Author Reply E583-E581; Author Reply E583

Letter by Bhupali and Labovitz regarding article, "Clinical scores for predicting recurrence after transient ischemic attack or stroke: how good are they?". Stroke 44(6): E71-E71

Letter by Bisdas et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial". Circulation 124(6): E194; Author Reply E195-6

Letter by Blackburn et al regarding article, "Is the Montreal cognitive assessment superior to the mini-mental state examination to detect poststroke cognitive impairment? A study with neuropsychological evaluation". Stroke 42(11): E582; Author Reply E583-E582; Author Reply E583

Letter by Blakey et al regarding article, "Mortality among high-risk patients with acute myocardial infarction admitted to US teaching-intensive hospitals in July: a retrospective observational study". Circulation 130(10): E93-E93

Letter by Bocelli et al regarding article, "A novel method of expressing left ventricular mass relative to body size in children". Circulation 119(2): E11; Author Reply E12-E11; Author Reply E12

Letter by Bogaard et al regarding article, "histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid". Circulation 127(14): E539-E539

Letter by Bohora regarding article, "Brugada-type electrocardiographic pattern induced by electrocution". Indian Pacing and Electrophysiology Journal 9(2): 106; Author Reply 107-106; Author Reply 107

Letter by Bollati et al regarding article, "Off-pump versus on-pump coronary artery bypass graft surgery: differences in short-term outcomes and in long-term mortality and need for subsequent revascularization". Circulation 117(10): E187; Author Reply E188-E187; Author Reply E188

Letter by Bonaque et al regarding article, "Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a randomized evaluation of long-term anticoagulation therapy (RE-LY) substudy". Circulation 127(2): E277-E277

Letter by Book et al regarding article, "pulmonary valve replacement in tetralogy of Fallot: impact on survival and ventricular tachycardia". Circulation 120(10): E79; Author Reply E80-E79; Author Reply E80

Letter by Boriani et al regarding article, "Death without prior appropriate implantable cardioverter-defibrillator therapy: a competing risk study". Circulation 118(14): E515; Author Reply E516-E515; Author Reply E516

Letter by Borja and Garcia-Rafanell regarding article, "Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association". Stroke 42(6): E388; Author Reply E386-E388; Author Reply E386

Letter by Boschetti et al regarding article, "Predictors of outcome in medically treated patients with acute coronary syndromes after angiographic triage: an Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) Substudy". Circulation 122(20): E523-E523

Letter by Bouchard et al regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients". Circulation 117(22): E475; Author Reply E476-E475; Author Reply E476

Letter by Bougouin et al regarding article, "sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes". Circulation 127(20): E633-E633

Letter by Bourantas et al regarding article, "nonculprit plaques in patients with acute coronary syndromes have more vulnerable features compared with those with non-acute coronary syndromes: a 3-vessel optical coherence tomography study". Circulation. Cardiovascular Imaging 5(6): E68-E68

Letter by Bouzas-Mosquera et al regarding article, "Cardiac magnetic resonance with T2-weighted imaging improves detection of patients with acute coronary syndrome in the emergency department". Circulation 119(17): E523; Author Reply E524-E523; Author Reply E524

Letter by Brandler and Sharma regarding article, "Does use of the recognition of stroke in the emergency room stroke assessment tool enhance stroke recognition by ambulance clinicians?". Stroke 45(2): E25-E25

Letter by Brewster and van Montfrans regarding article, "Risks associated with statin therapy: a systematic overview of randomized clinical trials". Circulation 116(1): E7; Author Reply E9-E7; Author Reply E9

Letter by Brodsky regarding article "Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses". Circulation. Arrhythmia and Electrophysiology 2(6): E44; Author Reply E45-6

Letter by Brook regarding article, "Residential exposure to traffic is associated with coronary atherosclerosis". Circulation 117(3): E16; Author Reply E17-E16; Author Reply E17

Letter by Brown and Pretorius regarding article, "effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients". Circulation 120(19): E159; Author Reply E160-E159; Author Reply E160

Letter by Brugaletta et al regarding article, "Vascular reactivity and flow characteristics of radial artery and long saphenous vein coronary bypass grafts: a 5-year follow-up". Circulation 123(15): E412; Author Reply E414-E412; Author Reply E414

Letter by Brugaletta et al. regarding article, "Interference of drug-eluting stents and endothelium-dependent coronary vasomotion: evidence for device-specific responses". Circulation. Cardiovascular Interventions 2(2): E1; Author Reply E2-E1; Author Reply E2

Letter by Bruno and Switzer regarding article, "Prestroke modified Rankin Stroke Scale has moderate interobserver reliability and validity in an acute stroke setting". Stroke 44(5): E43-E43

Letter by Bryan regarding article, "red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis". Circulation 123(3): E16; Author Reply E17-E16; Author Reply E17

Letter by Burchill et al regarding article, "Enalapril in infants with single ventricle: results of a multicenter randomized trial". Circulation 123(10): E373-E373

Letter by Burillo-Putze et al regarding article, "acute coronary syndrome and khat herbal amphetamine use: an observational report". Circulation 126(6): E84; Author Reply E87-8

Letter by Calvet et al regarding article, "Prevalence of coronary atherosclerosis in patients with cerebral infarction". Stroke 42(7): E406; Author Reply E407-E406; Author Reply E407

Letter by Canaud et al regarding article, "Retrograde ascending aortic dissection during or after thoracic aortic stent graft placement: insight from the European registry on endovascular aortic repair complications". Circulation 121(20): E413; Author Reply E414-E413; Author Reply E414

Letter by Cappellari et al regarding article, "statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and Randomized Trials". Stroke 44(6): E70-E70

Letter by Carapetis regarding article, "Is primary prevention of rheumatic fever the missing link in the control of rheumatic heart disease in Africa?". Circulation 121(15): E384; Author Reply E385-E384; Author Reply E385

Letter by Carin-Levy et al regarding article, "Delirium in acute stroke: a systematic review and meta-analysis". Stroke 43(7): E64; Author Reply E65-E64; Author Reply E65

Letter by Carmo et al regarding article, "High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease". Circulation 127(3): E354-E354

Letter by Carnero-Alcazar et al regarding article, "Quantification of incomplete revascularization and its association with five-year mortality in the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) Trial: validation of the residual SYNTAX Score". Circulation 129(8): E354-E354

Letter by Caruthers and Dorsch regarding article, "Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the platelet inhibition in children on cLOpidogrel (PICOLO) trial". Circulation 118(7): E120; Author Reply E121-E120; Author Reply E121

Letter by Casado-Arroyo et al regarding article, "Electrocardiographic characteristics and SCN5A mutations in idiopathic ventricular fibrillation associated with early repolarization". Circulation. Arrhythmia and Electrophysiology 5(2): E59; Author Reply E60-1

Letter by Casado-Naranjo et al regarding article, "using dabigatran in patients with stroke: a practical guide for clinicians". Stroke 43(5): E45; Author Reply E49-E45; Author Reply E49

Letter by Castilla-Guerra and Fernandez-Moreno regarding article, "Does abnormal circadian blood pressure pattern really matter in patients with transient ischemic attack or minor stroke?". Stroke 45(7): E130-E130

Letter by Cen regarding article, "Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas". Circulation 115(12): E348; Author Reply E349-E348; Author Reply E349

Letter by Chaix et al regarding article, "Impact of incident venous thromboembolism on risk of arterial thrombotic diseases". Circulation 130(21): E183-E183

Letter by Chakrabarti and Pererato regarding article, "smartphone teleradiology application is successfully incorporated into a telestroke network environment". Stroke 44(2): E11-E11

Letter by Chalmers regarding article "Nitinol stent implantation versus balloon angioplasty for lesions in the superficial femoral artery and proximal popliteal artery: twelve-month results from the RESILIENT randomized trial" . Circulation. Cardiovascular Interventions 3(5): E22; Author Reply E23-E22; Author Reply E23

Letter by Chao et al regarding article, "standard-dose intravenous tissue-type plasminogen activator for stroke is better than low doses". Stroke 45(12): E303-E303

Letter by Charidimou and Werring regarding article, "Cerebral microbleeds in the elderly". Stroke 42(4): E368-E368

Letter by Charidimou et al regarding article, "Blood pressure reduction, decreased diffusion on MRI, and outcomes after intracerebral hemorrhage". Stroke 43(3): E34; Author Reply E35-E34; Author Reply E35

Letter by Charitos et al regarding article, "Reoperation of left heart valve bioprostheses according to age at implantation". Circulation 125(15): E583-E583

Letter by Chatterjee and Chakraborty regarding article, "Mortality and readmission of patients with heart failure, atrial fibrillation, or coronary artery disease undergoing noncardiac surgery: an analysis of 38 047 patients". Circulation 125(6): E360; Author Reply E361-E360; Author Reply E361

Letter by Chaudhuri et al regarding article, "Differential clinical outcomes associated with hypoglycemia and hyperglycemia in acute myocardial infarction". Circulation 122(3): E396; Author Reply E397-E396; Author Reply E397

Letter by Chen and Zhang regarding article, "mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease". Circulation 126(6): E81; Author Reply E83-E81; Author Reply E83

Letter by Chen et al regarding article, "Neurological, functional, and cognitive stroke outcomes in Mexican Americans". Stroke 45(8): E167-E167

Letter by Chen et al regarding article, "Role of extracellular RNA in atherosclerotic plaque formation in mice". Circulation 130(16): E143-E143

Letter by Chen regarding article, "The impact of green tea and coffee consumption on the reduced risk of stroke incidence in Japanese population: the Japan public health center-based study cohort". Stroke 44(8): E90-E90

Letter by Cheong regarding article, "Association between stroke and patients with pelvic inflammatory disease: a nationwide population-based study in Taiwan". Stroke 42(10): E560; Author Reply E561-E560; Author Reply E561

Letter by Cheung et al regarding article, "Mild retinopathy is a risk factor for cardiovascular mortality in Japanese with and without hypertension: the Ibaraki Prefectural Health Study". Circulation 126(1): E13; Author Reply E14-E13; Author Reply E14

Letter by Chhabra and Spodick regarding article, "Influence of steroid therapy on the incidence of pericarditis and atrial fibrillation after percutaneous epicardial mapping and ablation for ventricular tachycardia" by Dyrda et al. Circulation. Arrhythmia and Electrophysiology 7(5): 991-991

Letter by Chhabra and Spodick regarding article, "Treatment of acute and recurrent idiopathic pericarditis". Circulation 128(19): E391-E391

Letter by Chin et al regarding article, "Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial analysis". Circulation 130(22): E194-E194

Letter by Choi et al regarding article, "Effects of the selective estrogen receptor modulator raloxifene on coronary outcomes in the raloxifene use for the heart trial: results of subgroup analyses by age and other factors". Circulation 120(17): E147; Author Reply E148-E147; Author Reply E148

Letter by Chung et al regarding article, "N-terminal pro B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure: primary results of the Canadian Prospective Randomized Multicenter IMPROVE-CHF study". Circulation 117(1): E5; Author Reply E6-E5; Author Reply E6

Letter by Chyrchel et al regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Circulation 129(13): E425-E425

Letter by Cingolani et al regarding article, "Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice". Circulation 120(15): E137; Author Reply E138-E137; Author Reply E138

Letter by Coffey et al regarding article, "Estimating deaths from cardiovascular disease: a review of global methodologies of mortality measurement". Circulation 128(6): E84-E84

Letter by Connelly et al regarding article, "Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension". Circulation 117(23): E483; Author Reply E484-E483; Author Reply E484

Letter by Conti and Volpe regarding article, "Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium". Circulation 115(13): E383; Author Reply E384-E383; Author Reply E384

Letter by Cornet et al regarding article, "Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest". Circulation 125(3): E287; Author Reply E289-E287; Author Reply E289

Letter by Corrado et al regarding article, "sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006". Circulation 120(16): E143; Author Reply E144-E143; Author Reply E144

Letter by Correia and Barreto-Filho regarding article, "Predictors of outcomes in medically treated patients with acute coronary syndromes after angiographic triage: an Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) Substudy". Circulation 122(20): E522-E522

Letter by Correia et al regarding article, "stress cardiac magnetic resonance imaging provides effective cardiac risk reclassification in patients with known or suspected stable coronary artery disease". Circulation 129(15): E450-E450

Letter by Cortese and Valgimigli regarding article, "Antithrombotic therapy in patients with chronic kidney disease". Circulation 126(21): E333; Author Reply E334-E333; Author Reply E334

Letter by Coutinho et al regarding article, "Mortality of cerebral venous-sinus thrombosis in a large national sample". Stroke 43(2): E22; Author Reply E23-E22; Author Reply E23

Letter by Covolo et al regarding article, "accurate assessment of aortic stenosis: a review of diagnostic modalities and hemodynamics". Circulation 130(15): E134-E134

Letter by Csont and Ferdinandy regarding article, "Biglycan is required for adaptive remodeling after myocardial infarction". Circulation 118(15): E521; Author Reply E522-E521; Author Reply E522

Letter by Csont and Ferdinandy regarding article, "ischemic conditioning protects the uremic heart in a rodent model of myocardial infarction". Circulation 126(13): E212; Author Reply E213-E212; Author Reply E213

Letter by Cundiff regarding editorial, "Cerebral venous thrombosis: another heparin controversy". Stroke 45(4): E65-E65

Letter by D'Alessandra et al regarding article, "Circulating microRNA-208b and microRNA-499 reflect myocardial damage in cardiovascular disease". Circulation. Cardiovascular Genetics 4(1): E7; Author Reply E8-E7; Author Reply E8

Letter by D'Anna et al regarding article, "Long-term mortality in patients with stroke of undetermined etiology". Stroke 44(1): E3-E3

Letter by Dai et al regarding article, "Targeting recombinant tissue-type plasminogen activator in acute ischemic stroke based on risk of intracranial hemorrhage or poor functional outcome: an analysis of the Third International Stroke Trial". Stroke 45(7): E132-E132

Letter by Dai et al regarding article, "cardiac resynchronization therapy in patients with heart failure and a QRS complex <120 milliseconds: the Evaluation of Resynchronization Therapy for Heart Failure (LESSER-EARTH) trial". Circulation 128(14): E217-E217

Letter by Dai et al regarding article, "time and diffusion lesion size in major anterior circulation ischemic strokes". Stroke 45(12): E305-E305

Letter by Dalzell regarding article, "outcomes of patients with peripartum cardiomyopathy who received mechanical circulatory support: data from the interagency registry for mechanically assisted circulatory support". Circulation. Heart Failure 7(4): 695-695

Letter by Damman et al regarding articles, "Long-term cardiovascular mortality after procedure-related or spontaneous myocardial infarction in patients with non-ST-segment elevation acute coronary syndrome: a collaborative analysis of individual patient data from the FRISC II, ICTUS, and RITA-3 Trials (FIR)" and "American College of Cardiology/American Heart Association/European Society of Cardiology/World Heart Federation universal definition of myocardial infarction classificati. Circulation 126(9): E136-7; Author Reply E138

Letter by Daneshvar regarding article, "Outcome of patients with low-gradient "severe" aortic stenosis and preserved ejection fraction". Circulation 124(13): E361; Author Reply E362-3

Letter by Daniels et al regarding article, "Incidence, causes, and survival trends from cardiovascular-related sudden cardiac arrest in children and young adults 0 to 35 years of age". Circulation 128(19): E390-E390

Letter by Daniels regarding article "Silent aspiration risk is volume-dependent". Dysphagia 27(2): 294; Author Reply 295-6

Letter by Dardas and Aaronson regarding article, "Impact of implantable cardioverter-defibrillator, amiodarone, and placebo on the mode of death in stable patients with heart failure: analysis from the sudden cardiac death in heart failure trial". Circulation 122(15): E486; Author Reply E487-E486; Author Reply E487

Letter by Dasi et al regarding article, "Effect of chronotropy and inotropy on stitch tension in the edge-to-edge mitral repair". Circulation 118(4): E78; Author Reply E79-E78; Author Reply E79

Letter by David et al regarding article, "Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) Randomized Trial". Circulation 127(11): E504-E504

Letter by De Backer et al regarding article, "Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study". Circulation 118(10): E151-E151

Letter by De Ferrari and Verrier regarding article, "Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy". Circulation 120(3): E20; Author Reply E22-E20; Author Reply E22

Letter by De Mattia et al regarding article, "Digital clubbing". Circulation 128(23): E448-E448

Letter by De Meyer et al regarding article "High von Willebrand factor levels increase the risk of stroke: the Rotterdam study". Stroke 42(3): E41-E41

Letter by De Miguel Castro et al regarding article, "Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the gauging responsiveness with a VerifyNow P2Y12 assay: impact on Thrombosis and Safety (GRAVITAS) trial". Circulation 125(14): E570; Author Reply E571-2

Letter by De Rango et al regarding article, "Predictors of abdominal aortic aneurysm sac enlargement after endovascular repair". Circulation 125(5): E340; Author Reply E342-3

Letter by De Servi and Navarese regarding article, "Prognostic modeling of individual patient risk and mortality impact of ischemic and hemorrhagic complications: assessment from the Acute Catheterization and Urgent Intervention Triage Strategy trial". Circulation 122(12): E461; Author Reply E462-3

Letter by DeGroff regarding article, "Direction of preoperative ventricular shunting affects ventricular mechanics after Tetralogy of Fallot repair". Circulation 120(6): E41-E41

Letter by DeGroff regarding article, "Rheumatic heart disease screening by echocardiography: The inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease". Circulation 121(21): E421; Author Reply E423-E421; Author Reply E423

Letter by Degraeuwe and Been regarding article, "Evidence of arteriolar narrowing in low-birth-weight children". Circulation 119(20): E537; Author Reply E538-E537; Author Reply E538

Letter by Delanaye et al regarding article, "Drawbacks and prognostic value of formulas estimating renal function in patients with chronic heart failure and systolic dysfunction". Circulation 115(11): E333-E333

Letter by Delewi et al regarding article, "Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis". Circulation 127(15): E547-E547

Letter by Derakhshan regarding article, "Intraoperative magnesium administration does not improve neurocognitive function following cardiac surgery". Stroke 45(3): E44-E44

Letter by Desai et al regarding article, "Role of balloon-expandable stents in intracranial atherosclerotic disease in a series of 182 patients". Stroke 44(10): E131-E131

Letter by Deutsch and Kaczmarek regarding article, "Donor pretreatment with hypertonic saline attenuates primary allograft dysfunction: a pilot study in a porcine model". Circulation 121(17): E393; Author Reply E394-E393; Author Reply E394

Letter by Deutsch et al regarding article, "Long-term outcomes of endoscopic vein harvesting after coronary artery bypass grafting". Circulation 124(10): E277; Author Response E278-E277; Author Response E278

Letter by Di Bella et al regarding article, "Effect of combined systolic and diastolic functional parameter assessment for differentiation of cardiac amyloidosis from other causes of concentric left ventricular hypertrophy". Circulation. Cardiovascular Imaging 7(1): 215-215

Letter by Di Bella et al. regarding the article "Agreement between ST elevation and late enhancement evaluated by MRI in patients with acute myocarditis". Journal of Electrocardiology 47(6): 954-955

Letter by Di Marco and Brand regarding article, "Reduction of circulating soluble fms-like tyrosine kinase-1 plays a significant role in renal dysfunction-associated aggravation of atherosclerosis". Circulation 122(5): E416; Athor Reply E417-E416; Athor Reply E417

Letter by DiDomenico et al regarding article, "Recent national trends in readmission rates after heart failure hospitalization". Circulation. Heart Failure 3(3): E13; Author Reply E17-E13; Author Reply E17

Letter by DiNicolantonio et al regarding article, "reducing sodium intake to prevent stroke: time for action, not hesitation". Stroke 45(6): E106-E107

Letter by Diamond regarding article, "Bayesian methods affirm the use of percutaneous coronary intervention to improve survival in patients with unprotected left main coronary artery disease". Circulation 129(4): E308-E308

Letter by Dias et al regarding article, "Pulmonary hypertensive medical therapy in chronic thromboembolic pulmonary hypertension before pulmonary thromboendarterectomy". Circulation 122(1): E1-E1

Letter by Dichgans et al regarding article, "Peripheral artery disease as a manifestation of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and practical implications". Circulation 128(17): E363-E363

Letter by Dillinger et al regarding article, "Drug resistance and pseudoresistance: an unintended consequence of enteric coating aspirin". Circulation 128(12): E189-E189

Letter by Dimitrow and Cheng regarding article, "Exercise testing in nonatherosclerotic heart disease: hypertrophic cardiomyopathy, valvular heart disease, and arrhythmias". Circulation 124(10): E276-E276

Letter by Dimitrow and Undas regarding article, "Functional impairment of von Willebrand factor in hypertrophic cardiomyopathy: relation to rest and exercise obstruction". Circulation 119(23): E590; Author Reply E591-E590; Author Reply E591

Letter by Ding and Mekary regarding article, "television viewing time and mortality: the Australian diabetes, obesity and lifestyle study (AusDiab)". Circulation 122(13): E472; Author Reply E473-E472; Author Reply E473

Letter by Dinh et al regarding the article, "Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure". Circulation. Heart Failure 3(4): E26; Author Reply E27-E26; Author Reply E27

Letter by Diomedi et al regarding article "continuous stroke unit electrocardiographic monitoring versus 24-hour holter electrocardiography for detection of paroxysmal atrial fibrillation after stroke". Stroke 44(2): E8-E8

Letter by Doehner et al regarding article, "Association between obesity and mortality after acute first-ever stroke: the obesity-stroke paradox". Stroke 42(6): E395; Author Reply E396-E395; Author Reply E396

Letter by Dokainish regarding article, "Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure". Circulation 120(7): E47-E47

Letter by Dominguez-Rodriguez et al regarding article, "C-reactive protein and the risk of stent thrombosis and cardiovascular events after drug-eluting stent implantation". Circulation 122(1): E2; Author Reply E3-E2; Author Reply E3

Letter by Dong et al regarding article, "CYP2C19 polymorphisms and antiplatelet effects of clopidogrel in acute ischemic stroke in China". Stroke 44(9): E107-E107

Letter by Doraiswamy regarding article, "Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study". Circulation 121(9): E235; Author Reply E236-E235; Author Reply E236

Letter by Doraiswamy regarding article, "Vascular reactivity and flow characteristics of radial artery and long saphenous vein coronary bypass grafts: a 5-year follow-up". Circulation 123(15): E413; Author Reply E414-E413; Author Reply E414

Letter by Dregelid regarding article, "Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia: a comparison of atherosclerotic peripheral arterial disease and Buerger disease". Circulation. Cardiovascular Interventions 4(2): E12; Author Reply E13-E12; Author Reply E13

Letter by Dregelid regarding article, "Intra-arterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA)". Circulation. Cardiovascular Interventions 4(3): E18-E18

Letter by Dregelid regarding article, "impact of femoral vascular closure devices and antithrombotic therapy on access site bleeding in acute coronary syndromes: the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial". Circulation. Cardiovascular Interventions 3(3): E12; Author Reply E13-E12; Author Reply E13

Letter by Drinka regarding article, "Low-density lipoprotein cholesterol concentrations and death due to intraparenchymal hemorrhage: the Ibaraki Prefectural Health Study". Circulation 120(25): E293-E293

Letter by Dumesnil and Pibarot regarding article, "Outcome of patients with low-gradient "severe" aortic stenosis and preserved ejection fraction". Circulation 124(13): E360; Author Reply E362-3

Letter by Dumesnil and Pibarot regarding article, "systemic hypertension in low-gradient severe aortic stenosis with preserved ejection fraction". Circulation 130(1): E5-E5

Letter by Duval et al regarding article, "Incidence of Infective endocarditis caused by viridans group streptococci before and after publication of the 2007 American Heart Association's endocarditis prevention guidelines". Circulation 127(12): E520-E520

Letter by Duyff and Groeneveld regarding article, "Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting". Stroke 43(8): E73; Author Reply E74-E73; Author Reply E74

Letter by Dwivedi et al regarding article, "Left ventricular untwisting rate by speckle tracking echocardiography". Circulation 117(19): E336; Author Reply E337-E336; Author Reply E337

Letter by Eastwood et Al regarding article, "association between postresuscitation partial pressure of arterial carbon dioxide and neurological outcome in patients with post-cardiac arrest syndrome". Circulation 129(1): E9-E9

Letter by Eberlein and Reed regarding article, "transplantation for idiopathic pulmonary arterial hypertension: improvement in the lung allocation score era". Circulation 129(16): E457-E457

Letter by Echavarría-Pinto and Escaned regarding article, "Thermodilution-derived coronary blood flow pattern immediately after coronary intervention as a predictor of microcirculatory damage and midterm clinical outcomes in patients with ST-segment-elevation myocardial infarction". Circulation. Cardiovascular Interventions 7(3): 417-417

Letter by Echouffo-Tcheugui and Kengne regarding article, "agreement among cardiovascular disease risk calculators". Circulation 128(21): E429-E429

Letter by Edelman et al regarding article, "Second internal thoracic artery versus radial artery in coronary artery bypass grafting: a long-term, propensity score-matched follow-up study". Circulation 125(17): E630; Author Reply E631-E630; Author Reply E631

Letter by Edelman et al regarding article, "Should off-pump coronary artery bypass grafting be abandoned?". Circulation 129(10): E386-E386

Letter by Egido and Garcia regarding article, "psychosocial distress and stroke risk in older adults". Stroke 44(5): E49-E49

Letter by Ehdaie and Rubin regarding article, "Long-term arrhythmia-free survival in patients with severe left ventricular dysfunction and no inducible ventricular tachycardia after myocardial infarction". Circulation 130(20): E177-E177

Letter by El Husseini et al regarding article, "What causes disability after transient ischemic attack and minor stroke?". Stroke 43(12): E180-E180

Letter by ElBardissi regarding article, "Outcome of alcohol septal ablation for obstructive hypertrophic cardiomyopathy". Circulation 119(4): E187; Author Reply E188-E187; Author Reply E188

Letter by Elkins et al regarding article, "blocking of α4 integrin does not protect from acute ischemic stroke in mice". Stroke 45(9): E195-E195

Letter by Eller et al regarding article, "Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland". Circulation 121(14): E377-E377

Letter by Ellims et al regarding article, "myocardial tissue characterization using magnetic resonance noncontrast t1 mapping in hypertrophic and dilated cardiomyopathy". Circulation. Cardiovascular Imaging 6(2): E1-E1

Letter by Elshazly Regarding Article "Primary Coronary Angioplasty for ST-Elevation Myocardial Infarction (STEMI) in Qatar: First Nationwide Program". Global Cardiology Science & Practice 2013(1): 80-81

Letter by Erdoes et al regarding article, "cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study". Circulation 127(18): E590-E590

Letter by Espinoza regarding article, "Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia". Circulation 125(12): E521; Author Reply E523-4

Letter by Falk regarding article, "An unusual heart failure: cardiac amyloidosis due to light chain myeloma". Circulation 124(20): E534; Author Reply E535-E534; Author Reply E535

Letter by Fan and He regarding article, "Cost-effectiveness of percutaneous coronary intervention in patients with stable coronary disease and abnormal fractional flow reserve". Circulation 129(25): E683-E683

Letter by Fan et al regarding article, "Additive value of magnetic resonance coronary angiography in a comprehensive cardiac magnetic resonance stress-rest protocol for detection of functionally significant coronary artery disease: a pilot study". Circulation. Cardiovascular Imaging 6(6): E75-E75

Letter by Fanning et al regarding article, "Histopathology of embolic debris captured during transcatheter aortic valve replacement". Circulation 128(25): E477-E477

Letter by Farmakis and Aessopos regarding article, "echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United kingdom". Circulation 125(19): E930-E930

Letter by Faul et al regarding article, "Percutaneous femoral arteriovenous shunt creation for advanced chronic obstructive pulmonary disease: a single-center safety and efficacy study". Circulation. Cardiovascular Interventions 5(3): E45; Author Reply E46-E45; Author Reply E46

Letter by Fayssoil regarding article, "Determinants of surgical outcome in patients with isolated tricuspid regurgitation". Circulation 122(2): E13; Author Reply E15-E13; Author Reply E15

Letter by Fayssoil regarding article, "Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice". Circulation 125(9): E429-E429

Letter by Fazio and Carlomagno regarding article, "Heart rate predicts outcomes in an implantable cardioverter-defibrillator population". Circulation 121(24): E451; Author Reply E452-E451; Author Reply E452

Letter by Fearon regarding article, "Primary coronary microvascular dysfunction: clinical presentation, pathophysiology, and management". Circulation 123(4): E212; Author Reply E213-E212; Author Reply E213

Letter by Ferdinand et al regarding article, "Does black ethnicity influence the development of stent thrombosis in the drug-eluting stent era?". Circulation 123(22): E621; Author Reply 623-E621; Author Reply 623

Letter by Ferrante et al regarding article, "impact of collateral flow to the occluded infarct-related artery on clinical outcomes in patients with recent myocardial infarction: a report from the randomized occluded artery trial". Circulation 123(8): E256; Author Reply E257-8

Letter by Ferrari et al regarding article, "Long-term arrhythmia-free survival in patients with severe left ventricular dysfunction and no inducible ventricular tachycardia after myocardial infarction". Circulation 130(20): E178-E178

Letter by Filgueiras-Rama et al regarding article, "Maximal electric separation-guided placement of right ventricular lead improves responders in cardiac resynchronization defibrillator therapy" by Miranda et al. Circulation. Arrhythmia and Electrophysiology 6(2): E24-E24

Letter by Filippidis et al regarding article, "Evaluating strategies for the treatment of cerebral cavernous malformations". Stroke 42(5): E373-E373

Letter by Filis et al regarding article, "Non-ST-elevation myocardial infarction in patients undergoing carotid endarterectomy or carotid artery stent placement". Stroke 45(5): E89-E89

Letter by Fillinger regarding article, "Predictors of abdominal aortic aneurysm sac enlargement after endovascular repair". Circulation 125(5): E341; Author Reply E342-3

Letter by Fisher and Johns regarding article, "Variable platelet response to aspirin and clopidogrel in atherothrombotic disease". Circulation 116(19): E521-E521

Letter by Foin et Al regarding article, "edge effect from drug-eluting stents as assessed with serial intravascular ultrasound: a systematic review". Circulation. Cardiovascular Interventions 5(5): E70; Author Reply E71-E70; Author Reply E71

Letter by Forfia and Borlaug regarding article, "Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study". Circulation 125(8): E408; Author Reply E409-10

Letter by Fort and Plachetka regarding article, "association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from PLATO". Circulation 126(11): E170; Author Reply E171-2

Letter by Fragasso et al regarding article by Tuunanen et al, "Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure". Circulation 115(21): E546; Author Reply E547-E546; Author Reply E547

Letter by Frans and Koelemay regarding article, "supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) study". Circulation 126(7): E100; Author Reply E102-3

Letter by Freeman and Taussky regarding article, "Near infrared spectroscopy for the detection of desaturations in vulnerable ischemic brain tissue: a pilot study at the stroke unit bedside". Stroke 43(7): E61; Author Reply E62-E61; Author Reply E62

Letter by Freeman et al regarding article, "Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY Trial". Stroke 43(7): E63-E63

Letter by Freeman et al regarding article, "Very early mobilization after stroke fast-tracks return to walking: further results from the phase II AVERT randomized controlled trial". Stroke 42(5): E375-E375

Letter by Freeman et al regarding article, "using dabigatran in patients with stroke: a practical guide for clinicians". Stroke 43(5): E48; Author Reply E49-E48; Author Reply E49

Letter by Fresco regarding article "Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish Acute Myocardial Infarction 2 trial". Circulation 122(25): E640; Author Reply E641-E640; Author Reply E641

Letter by Frydrychowicz and Markl regarding article, "Association between aneurysm shoulder stress and abdominal aortic aneurysm expansion: a longitudinal follow-up study". Circulation 123(25): E643; Author Reply E644-E643; Author Reply E644

Letter by Fu et al. regarding the article, "Polymorphisms in the vitamin D receptor gene and the lung cancer risk". Tumour Biology 35(2): 921-922

Letter by Fuentes and Diez-Tejedor regarding article, "Anticoagulants for cerebral venous thrombosis: harmful to patients?". Stroke 45(5): E91-E91

Letter by Fuentes et al regarding article, "J-shaped association between serum glucose and functional outcome in acute ischemic stroke". Stroke 42(4): E361; Author Reply E362-E361; Author Reply E362

Letter by Furlan regarding "critique of closure or medical therapy for cryptogenic stroke with patent foramen ovale: the hole truth?". Stroke 44(2): E9-E9

Letter by Fürstenwerth regarding article, "aspirin: a historical and contemporary therapeutic overview". Circulation 124(12): E332; Author Reply E333-E332; Author Reply E333

Letter by G. Studer, U. M. Luetolf, C. Glanzmann on the comment by H. Christiansen & C. F. Hess. Locoregional failure analysis in head and neck cancer patients treated with IMRT. Strahlentherapie und Onkologie 183(10): 581-582

Letter by Gaberel et Al regarding article, "dose effect of intraventricular fibrinolysis in ventricular hemorrhage". Stroke 42(9): E548-9; Author Reply E550

Letter by Gaberel et al regarding article, "fibrinolysis for intraventricular hemorrhage: an updated meta-analysis and systematic review of the literature". Stroke 45(11): E235-E235

Letter by Gaibazzi regarding article, "Usefulness of 64-slice cardiac computed tomographic angiography for diagnosing acute coronary syndromes and predicting clinical outcome in emergency department patients with chest pain of uncertain origin". Circulation 116(12): E354; Author Reply E355-E354; Author Reply E355

Letter by Gaillard et al regarding article, "Thrombolysis despite recent stroke: a case series". Stroke 44(8): E99-E99

Letter by Galderisi and Esposito regarding article, "Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure". Circulation 120(7): E46-E46

Letter by Gale et al regarding article, "which hospitals have significantly better or worse than expected mortality rates for acute myocardial infarction patients? Improved risk adjustment with present-at-admission diagnoses". Circulation 118(1): E9; Author Reply E10-E9; Author Reply E10

Letter by Gallerini et al regarding article, "Characteristics and outcomes of patients with multiple cervical artery dissection". Stroke 45(5): E90-E90

Letter by Galyfos et Al regarding article, "N-terminal pro-B-type natriuretic peptide and stroke risk: the reasons for geographic and racial differences in stroke cohort". Stroke 45(9): E197-E197

Letter by Garcia-Garcia et al regarding article, "Impact of frequency-domain optical coherence tomography guidance for optimal coronary stent implantation in comparison with intravascular ultrasound guidance". Circulation. Cardiovascular Interventions 5(4): E59; Author Reply E60-E59; Author Reply E60

Letter by Gasparini and Boriani regarding article, "Cardiac resynchronization therapy in patients with permanent atrial fibrillation: results from the Resynchronization for Ambulatory Heart Failure Trial (RAFT)". Circulation. Heart Failure 6(2): E22-E22

Letter by Gasparini regarding article, "syncope in high-risk cardiomyopathy patients with implantable defibrillators: frequency, risk factors, mechanisms, and association with mortality: results from the Multicenter Automatic Defibrillator Implantation Trial-Reduce Inappropriate Therapy (MADIT-RIT) study". Circulation 130(15): E132-E132

Letter by Gasparovic and Kopjar regarding article, "rhythm versus rate control therapy and subsequent stroke or transient ischemic attack in patients with atrial fibrillation". Circulation 128(3): E41-E41

Letter by Gasparovic et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial". Circulation 124(6): E193; Author Reply E195-6

Letter by Gasparrini and Gorini regarding article, "Effect of the Italian smoking ban on population rates of acute coronary events". Circulation 118(9): E139; Author Reply E140-E139; Author Reply E140

Letter by Gavriilaki et al regarding article, "Bacterial signatures in thrombus aspirates of patients with myocardial infarction". Circulation 128(15): E236-E236

Letter by Geier et al regarding article, "Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction". Circulation 115(23): E622; Author Reply E623-E622; Author Reply E623

Letter by George regarding article, "Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled cross-over preliminary study". Circulation. Heart Failure 3(3): E10; Author Reply E14-E10; Author Reply E14

Letter by Giannini et al regarding article, "cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study". Circulation 127(18): E589-E589

Letter by Giardini et al regarding article, "Maladaptive aortic properties in children after palliation of hypoplastic left heart syndrome assessed by cardiovascular magnetic resonance imaging". Circulation 123(19): E594; Author Reply E595-E594; Author Reply E595

Letter by Giblett and Hoole regarding article, "Remote ischemic postconditioning during percutaneous coronary interventions: remote ischemic postconditioning-percutaneous coronary intervention randomized trial". Circulation. Cardiovascular Interventions 7(3): 422-422

Letter by Giglio and Mangiola regarding article, "Cardiomyopathy in Duchenne muscular dystrophy carrier and her diseased son: similar pattern revealed by cardiovascular MRI". Circulation 122(7): E431; Author Reply E432-E431; Author Reply E432

Letter by Giral et al regarding article, "lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER trial (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin)". Circulation 130(17): E151-E151

Letter by Girdauskas regarding article, "Aortic dilation in bicuspid aortic valve disease: flow pattern is a major contributor and differs with valve fusion type". Circulation. Cardiovascular Imaging 7(1): 213-213

Letter by Gloekler et al regarding article, "Enhanced external counterpulsation improves peripheral artery flow-mediated dilation in patients with chronic angina: a randomized sham-controlled study". Circulation 123(23): E631-E631

Letter by Gnecchi-Ruscone and Guazzi regarding article, "Duration of QRS complex in resting electrocardiogram is a predictor of sudden cardiac death in men". Circulation 126(22): E337; Author Reply E338-E337; Author Reply E338

Letter by Goetze et al regarding article, "B-type natriuretic peptide signal peptide circulates in human blood: evaluation as a potential biomarker of cardiac ischemia". Circulation 123(6): E232; Author Reply E234-E232; Author Reply E234

Letter by Goldstein et al regarding article, "Risk factors for abdominal aortic aneurysms: a 7-year prospective study: the Tromso study". Circulation 121(1): E7; Author Reply E8-E7; Author Reply E8

Letter by Golledge regarding article, "Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stenting". Circulation 116(21): E545; Author Reply E546-E545; Author Reply E546

Letter by Gomes and Evora regarding article, "Early on-cardiopulmonary bypass hypotension and other factors associated with vasoplegic syndrome". Circulation 121(22): E431-E431

Letter by Gomez et al regarding article, "Colchicine reduces postoperative atrial fibrillation: results of the colchicine for the prevention of the postpericardiotomy syndrome (COPPS) atrial fibrillation substudy". Circulation 125(25): E1053; Author Reply E1054-E1053; Author Reply E1054

Letter by Gomez-Ambrosi et al regarding article, "clinical assessment and management of adult obesity". Circulation 128(3): E39-E39

Letter by Gomez-Choco and Valdueza regarding article, "posterior cerebral artery laterality on magnetic resonance angiography predicts functional outcome". Stroke 44(5): E51-E51

Letter by Gonzalez and Liebeskind regarding article, "remote ischemic limb preconditioning after subarachnoid hemorrhage: a phase Ib study of safety and feasibility". Stroke 42(9): E553-E553

Letter by Goodman and Sax regarding article, "Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects". Circulation 127(4): E432-E432

Letter by Gordon et al regarding article, "Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study". Circulation 125(8): E406; Author Reply E409-10

Letter by Gourdie and Sedmera regarding article, "abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal-targeted deletion of Alk3/Bmpr1a receptor". Circulation 118(6): E106; Author Reply E107-E106; Author Reply E107

Letter by Govindarajan and Salgado regarding article, "Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial". Circulation 125(3): E290; Author Reply E293-4

Letter by Grbel et al regarding article, "administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome". Circulation. Cardiovascular Interventions 7(2): 273-273

Letter by Greenberg regarding article, "Continuous aortic flow augmentation: not enough MOMENTUM". Circulation 119(14): E389; Author Reply E390-E389; Author Reply E390

Letter by Greyson regarding article, "High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury". Circulation 118(21): E703; Author Reply E704-E703; Author Reply E704

Letter by Griebe et al regarding article, "Jugular veins in transient global amnesia: innocent bystanders". Stroke 43(11): E165; Author Reply E166-E165; Author Reply E166

Letter by Grove and Kristensen regarding article, "Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction". Circulation. Cardiovascular Interventions 6(2): E28-E28

Letter by Grover et al regarding article, "Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg First-in-Man study". Circulation 115(22): E612; Author Reply E613-E612; Author Reply E613

Letter by Guarracino et al regarding article, "Direct myocardial effects of levosimendan in humans with left ventricular dysfunction: alteration of force-frequency and relaxation-frequency relationships". Circulation 116(11): E346; Author Reply E347-E346; Author Reply E347

Letter by Guazzi et al regarding article, "Comprehensive use of cardiopulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term". Circulation 126(8): E122; Author Reply E123-E122; Author Reply E123

Letter by Guettrot-Imbert et al regarding article, "early diagnosis and treatment of atrioventricular block in the fetus exposed to maternal anti-SSA/Ro-SSB/La antibodies". Circulation 120(21): E167; Author Reply E168-E167; Author Reply E168

Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement". Circulation 122(14): E478; Author Reply E479-E478; Author Reply E479

Letter by Gómez-Choco and García regarding article "spectrum of transient focal neurological episodes in cerebral amyloid angiopathy". Stroke 43(10): E107; Author Reply E108-E107; Author Reply E108

Letter by Habib and Schwann regarding article, "Bilateral internal mammary artery grafting enhances survival in diabetic patients: a 30-year follow-up of propensity score-matched cohorts". Circulation 128(5): E72-E72

Letter by Haft regarding article, "High prevalence of atrial fibrillation among patients with ischemic stroke". Stroke 46(1): E11-E11

Letter by Haines regarding article, "Direct measurement of the lethal isotherm for radiofrequency ablation of myocardial tissue". Circulation. Arrhythmia and Electrophysiology 4(5): E67; Author Reply E68-E67; Author Reply E68

Letter by Hakeem et al regarding article, "Drug-eluting or bare metal stents for the treatment of saphenous vein graft disease: a Bayesian meta-analysis". Circulation. Cardiovascular Interventions 4(2): E14; Author Reply E15-E14; Author Reply E15

Letter by Halcox regarding article, "OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction". Circulation 124(1): E21; Author Reply E24-5

Letter by Halle regarding article, "Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients". Circulation 127(21): E637-E637

Letter by Hamilton and Filardo regarding article, "Reduced ventricular volumes and improved systolic function with cardiac resynchronization therapy: a randomized trial comparing simultaneous biventricular pacing, sequential biventricular pacing, and left ventricular pacing". Circulation 117(3): E14; Author Reply E15-E14; Author Reply E15

Letter by Hamilton regarding article, "Prophylactic radiofrequency ablation in asymptomatic patients with Wolff-Parkinson-White is not yet a good strategy: a decision analysis". Circulation. Arrhythmia and Electrophysiology 6(3): E38-E38

Letter by Hamilton-Craig et al regarding article, "Posttraumatic cardiac contrecoup: in vivo evidence by cardiac magnetic resonance imaging". Circulation 120(18): E155; Author Reply E156-E155; Author Reply E156

Letter by Hamilton-Craig et al regarding article, "role of cardiovascular magnetic resonance as a gatekeeper to invasive coronary angiography in patients presenting with heart failure of unknown etiology". Circulation 125(24): E1041; Author Reply E1042-E1041; Author Reply E1042

Letter by Hammoud et al regarding article "Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition". Circulation 115(24): E637; Author Reply E638-E637; Author Reply E638

Letter by Hamon et al regarding article, "Coronary multidetector computed tomography in the assessment of patients with acute chest pain". Circulation 115(18): E448; Author Reply E449-E448; Author Reply E449

Letter by Hansel and Simon regarding article, "Body mass index and vigorous physical activity and the risk of heart failure among men". Circulation 120(11): E90; Author Reply E91-E90; Author Reply E91

Letter by Hanss regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke". Stroke 44(4): E36-E36

Letter by Harder et al regarding article, "Low birth weight, a risk factor for cardiovascular diseases in later life, is already associated with elevated fetal glycosylated hemoglobin at birth". Circulation 115(19): E462; Author Reply E463-4

Letter by Harris et al regarding article, "outcomes of patients with acute type a aortic intramural hematoma". Circulation 121(25): E456; Author Reply E457-E456; Author Reply E457

Letter by Hartog et al. regarding article, "Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines". Circulation 119(10): E233; Author Reply E234-E233; Author Reply E234

Letter by Hasnain and Vieweg regarding article, "Myocardial infarction and risk of suicide: a population-based case-control study". Circulation 124(3): E51-2; Author Reply E53

Letter by Hattler et al regarding article, "Graft patency after off-pump coronary artery bypass surgery". Circulation 127(2): E276-E276

Letter by Haufe et al regarding article, "Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation". Circulation. Heart Failure 5(6): E100; Author Reply E101-E100; Author Reply E101

Letter by Hayashi et al regarding article, "Heritability of early repolarization: a population-based study". Circulation. Cardiovascular Genetics 4(5): E20; Author Reply E21-E20; Author Reply E21

Letter by Heegaard et al regarding article, "sudden cardiac arrest and death following application of shocks from a TASER electronic control device". Circulation 127(1): E260-E260

Letter by Heidrich et al regarding article, "Inositol 1,4,5-trisphosphate receptors and human left ventricular myocytes". Circulation 129(21): E509-E509

Letter by Heling et al regarding article, "remote ischemic preconditioning in human coronary artery bypass surgery: from promise to disappointment?". Circulation 123(17): E424; Reply E425-E424; Reply E425

Letter by Henrikson regarding article, "Endocarditis secondary to Microsporidia: giant vegetation in a pacemaker user". Circulation 121(1): E4; Author Reply E5-E4; Author Reply E5

Letter by Herring and Paterson regarding article, "Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study". Circulation 116(24): E564; Author Reply E565-E564; Author Reply E565

Letter by Heston regarding article, "comparative effectiveness of exercise electrocardiography with or without myocardial perfusion single photon emission computed tomography in women with suspected coronary artery disease: results from the What Is the Optimal Method for Ischemia Evaluation in Women (WOMEN) trial". Circulation 125(19): E933; Author Reply E932-5

Letter by Hibbert et al regarding article, "Smooth muscle cells healing atherosclerotic plaque disruptions are of local, not blood, origin in apolipoprotein E knockout mice". Circulation 117(16): E317; Author Reply E318-E317; Author Reply E318

Letter by Hiemann et al regarding article, "Assessment of microcirculatory remodeling with intracoronary flow velocity and pressure measurements: validation with endomyocardial sampling in cardiac allografts". Circulation 122(4): E404; Author Reply E405-E404; Author Reply E405

Letter by Hifumi et al regarding article, "Management and outcomes of major bleeding during treatment with dabigatran or warfarin". Circulation 130(10): E94-E94

Letter by Hill et al regarding article, "A cost-utility analysis of mechanical thrombectomy as an adjunct to intravenous tissue-type plasminogen activator for acute large-vessel ischemic stroke". Stroke 42(12): E641-2; Author Reply E643

Letter by Hill et al. regarding article, "Mortality in first 5 years in infants with functional single ventricle born in Texas, 1996 to 2003". Circulation 122(16): E491; Author Reply E492-E491; Author Reply E492

Letter by Hiltunen and Jolkkonen regarding article, "secondary neurodegeneration in remote regions after focal cerebral infarction: a new target for stroke management?". Stroke 43(9): E96; Author Reply E97-E96; Author Reply E97

Letter by Hjemdahl et al regarding article, "Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial". Circulation 127(11): E505-E505

Letter by Hnid and Chtioui regarding article, "Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Registry". Circulation 124(11): E297-E297

Letter by Ho and Dawes regarding article, "sudden cardiac arrest and death following application of shocks from a TASER electronic control device". Circulation 127(1): E259-E259

Letter by Hobai regarding article, "Long-term anabolic-androgenic steroid use is associated with left ventricular dysfunction". Circulation. Heart Failure 3(6): E30; Author Reply E31-E30; Author Reply E31

Letter by Hong et al regarding article, "Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation". Circulation 118(16): E668; Author Reply E669-E668; Author Reply E669

Letter by Hope et al regarding article, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy". Circulation 130(19): E170-E170

Letter by House et al regarding article, "Prosthesis-patient mismatch in bovine pericardial aortic valves: evaluation using 3 different modalities and associated medium-term outcomes". Circulation. Cardiovascular Imaging 7(1): 209-209

Letter by Houthuizen et al regarding article, "Clinical impact of persistent left bundle-branch block after transcatheter aortic valve implantation with CoreValve revalving system". Circulation 128(22): E443-E443

Letter by Hugli regarding article, "Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience". Circulation 121(4): E23; Author Reply E24-E23; Author Reply E24

Letter by Huijts et al regarding article, "cerebral microbleeds and cognition in patients with symptomatic small vessel disease". Stroke 44(6): E69-E69

Letter by Huon and Wang regarding article, "Risk of stroke in patients hospitalized for isolated vertigo: a 4-year follow-up study". Stroke 42(6): E392; Author Reply E393-4

Letter by Huzen et al regarding article, "Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study". Circulation 118(19): E688; Author Reply E689-E688; Author Reply E689

Letter by Hyder and Barbara regarding article, "perioperative dexmedetomidine improves outcomes of cardiac surgery". Circulation 128(16): E336-E336

Letter by Höglund and Nilsson regarding article, "influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure". Circulation 118(1): E7; Author Reply E8-E7; Author Reply E8

Letter by Iascone et al regarding article, "Population-based variation in cardiomyopathy genes". Circulation. Cardiovascular Genetics 5(6): E57; Author Reply E58-E57; Author Reply E58

Letter by Ibrahim et al regarding article "Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis". Circulation 122(22): E566; Author Reply E567-E566; Author Reply E567

Letter by Iles and Taylor regarding article, "Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume". Circulation. Cardiovascular Imaging 6(4): E25-E25

Letter by Iliodromitis et al regarding article, "Cardiac Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study: a prospective, randomized control trial". Circulation 120(14): E130; Author Reply E133-E130; Author Reply E133

Letter by Ince and Benbir regarding article, "long-term mortality in patients with stroke of undetermined etiology". Stroke 44(3): E17-E17

Letter by Iosa et al regarding article, "Reliability and validity of bilateral ankle accelerometer algorithms for activity recognition and walking speed after stroke". Stroke 42(11): E576; Author Reply E577-E576; Author Reply E577

Letter by Irion regarding article, "systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies". Circulation 127(9): E477-E477

Letter by Jaeggi et al regarding article, "Perinatal outcome of fetal atrioventricular block: one-hundred sixteen cases from a single institution". Circulation 119(20): E539; Author Reply E541-2

Letter by Jamous regarding article, "Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study". Circulation 125(8): E407; Author Reply E409-10

Letter by Janket et al regarding article, "Use and misuse of the receiver operating characteristic curve in risk prediction". Circulation 116(6): E133; Author Reply E134-E133; Author Reply E134

Letter by Jansen and van Royen regarding article, "Monitoring of monocyte recruitment in reperfused myocardial infarction with intramyocardial hemorrhage and microvascular obstruction by combined fluorine-19 and proton cardiac magnetic resonance imaging". Circulation 130(5): E40-E40

Letter by Januzzi regarding article, "galectin-3 and cardiac function in survivors of acute myocardial infarction". Circulation. Heart Failure 6(4): E57-E57

Letter by Jaquinandi et al regarding article, "Different calculations of ankle-brachial index and their impact on cardiovascular risk prediction". Circulation 119(18): E527; Author Reply E528-E527; Author Reply E528

Letter by Jeilan et al regarding article, "Longitudinal strain delay index by speckle tracking imaging: a new marker of response to cardiac resynchronization therapy". Circulation 119(25): E599; Autjhor Reply E600-E599; Autjhor Reply E600

Letter by Jenner and Portraits of Francis Home, of Edinburgh (1719-1813). Proceedings of the Royal Society of Medicine 20(5): 584-585

Letter by Jennings regarding article, "Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices". Circulation. Heart Failure 5(6): E102; Author Reply E103-E102; Author Reply E103

Letter by Jin et al regarding article, "ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension". Circulation 129(20): E499-E499

Letter by Joffe et al regarding article, "Duration of cardiopulmonary resuscitation and illness category impact survival and neurologic outcomes for in-hospital pediatric cardiac arrests". Circulation 128(7): E101-E101

Letter by Johansson et al regarding article, "Migraine Intervention With STARFlex Technology (MIST) trial". Circulation 119(5): E193; Author Reply E194-E193; Author Reply E194

Letter by Johnson et al regarding article, "Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry". Circulation. Cardiovascular Interventions 6(2): E26-E26

Letter by Jones et al regarding article, "Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation". Circulation 129(24): E655-E655

Letter by Jong et al regarding article, "dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults". Circulation 118(8): E129; Author Reply E130-E129; Author Reply E130

Letter by Joshi regarding article, "Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial nuclear substudy". Circulation 118(25): E838; Author Reply E840-1

Letter by Joynt and Edelman regarding article, "Iatrogenic giant Osborn waves". Circulation 123(12): E390; Author Reply E391-E390; Author Reply E391

Letter by Kagawa et al regarding article, "hypothermia in comatose survivors from out-of-hospital cardiac arrest: pilot trial comparing 2 levels of target temperature". Circulation 128(4): E55-E55

Letter by Kalita et al regarding article, "Association between obesity and mortality after acute first-ever stroke: the obesity-stroke paradox". Stroke 42(5): E379; Author Reply E380-E379; Author Reply E380

Letter by Kan et al regarding Article, "randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart failure (WATCH) trial". Circulation 120(20): E164-E164

Letter by Kaneda and Terashima regarding article, "the long-term effect of coronary stenting on epicardial and microvascular endothelial function". Circulation. Cardiovascular Interventions 6(1): E7-E7

Letter by Kaneda regarding article, "Effect of rosuvastatin therapy on coronary artery stenoses assessed by quantitative coronary angiography: a study to evaluate the effect of rosuvastatin on intravascular ultrasound-derived coronary atheroma burden". Circulation 118(22): E706; Author Reply E708-9

Letter by Kaneda regarding article, "Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION study". Circulation 127(10): E488-E488

Letter by Kaplan regarding article, "Bacteremia associated with toothbrushing and dental extraction". Circulation 119(2): E13; Author Reply E14-E13; Author Reply E14

Letter by Karabay et al regarding article, "fractional flow reserve assessment of left main stenosis in the presence of downstream coronary stenoses". Circulation. Cardiovascular Interventions 6(4): E56-E56

Letter by Karam and Marijon regarding article, "Atrial fibrillation: outpatient presentation and management". Circulation 125(4): E317; Author Reply E319-E317; Author Reply E319

Letter by Karkouti and Beattie regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients". Circulation 117(22): E472; Author Reply E476-E472; Author Reply E476

Letter by Karthikeyan et al regarding article, "Acute rheumatic fever and rheumatic heart disease: incidence and progression in the Northern Territory of Australia, 1997 to 2010". Circulation 129(11): E396-E396

Letter by Kasivisvanathan et al regarding article, "stenting versus surgery in patients with carotid stenosis after previous cervical radiation therapy: systematic review and meta-analysis". Stroke 43(5): E50; Author Reply E51-E50; Author Reply E51

Letter by Kasprowicz et al regarding article, "reducing sodium intake to prevent stroke: time for action, not hesitation". Stroke 45(6): E108-E108

Letter by Kass regarding article, "Role of left ventricular stiffness in heart failure with normal ejection fraction". Circulation 119(1): E4; Author Reply E5-E4; Author Reply E5

Letter by Katz regarding article, "television viewing time and mortality: the Australian Diabetes, Obesity and Lifestyle study (AusDiab)". Circulation 122(13): E471; Author Reply E473-E471; Author Reply E473

Letter by Kaufman regarding article, "Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough?". Circulation 121(23): E439; Author Reply E440-E439; Author Reply E440

Letter by Kavsak and MacRae regarding article, "Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction". Circulation 125(6): E358; Author Reply E359-E358; Author Reply E359

Letter by Kavsak et al regarding article, "B-type natriuretic peptide signal peptide circulates in human blood: evaluation as a potential biomarker of cardiac ischemia". Circulation 123(6): E233; Author Reply E234-E233; Author Reply E234

Letter by Kawada regarding article, "Dabigatran versus warfarin: effects on ischemic and hemorrhagic strokes and bleeding in Asians and non-Asians with atrial fibrillation". Stroke 44(10): E134-E134

Letter by Kawada regarding article, "Sleep duration and risk of stroke mortality among Chinese adults: Singapore Chinese Health Study". Stroke 45(7): E134-E134

Letter by Keidar and Gamliel-Lazarovich regarding article, "Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trial". Circulation 125(18): E653; Author Reply E654-E653; Author Reply E654

Letter by Kelland and Roberts regarding article, "Lipid management to reduce cardiovascular risk: a new strategy is required". Circulation 118(7): E119-E119

Letter by Kereiakes et al regarding article, "Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern". Circulation 116(16): E389; Author Reply E390-E389; Author Reply E390

Letter by Kern regarding article "Primary stenting of an anomalous left main coronary artery with an interarterial course during cardiac arrest: imaging with CT angiography". Circulation. Cardiovascular Imaging 2(6): E51; Author Reply E52-E51; Author Reply E52

Letter by Kern regarding article, "High-pressure loculated pericardial effusion in postpericardiotomy syndrome". Circulation 126(23): E342; Author Reply E343-E342; Author Reply E343

Letter by Kern regarding article, "comparison of clinical interpretation with visual assessment and quantitative coronary angiography in patients undergoing percutaneous coronary intervention in contemporary practice: the assessing angiography (A2) project". Circulation 128(24): E461-E461

Letter by Kerr and Lees regarding article, "country comparisons of human stroke research since 2001: a bibliometric study". Stroke 43(5): E52-E52

Letter by Kessler regarding article, "Effect of short call admissions on length of stay and quality of care for acute decompensated heart failure". Circulation 119(1): E6; Author Reply E7-E6; Author Reply E7

Letter by Khan et al regarding article "Efficacy of antibiotic prophylaxis before the implantation of pacemakers and cardioverter-defibrillators: results of a large, prospective, randomized, double-blinded, placebo-controlled trial". Circulation. Arrhythmia and Electrophysiology 2(3): E13; Author Reply E14-E13; Author Reply E14

Letter by Khan et al regarding article, "Hospital-level variation in mortality and rehospitalization for Medicare beneficiaries with acute ischemic stroke". Stroke 42(7): E404; Author Reply E405-E404; Author Reply E405

Letter by Khandelwal regarding article, "comparison of clinical interpretation with visual assessment and quantitative coronary angiography in patients undergoing percutaneous coronary intervention in contemporary practice: the assessing angiography (A2) project". Circulation 128(24): E462-E462

Letter by Kharabish and Fratz regarding article, "Implications of early aortic stiffening in patients with transposition of the great arteries after arterial switch operation". Circulation. Cardiovascular Imaging 6(4): E23-E23

Letter by Kielstein et al regarding article, "High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid". Circulation 115(18): E450-1; Author Reply E451

Letter by Kirchoff-Torres and Labovitz regarding article, "Lifelong rupture risk of intracranial aneurysms depends on risk factors: a prospective Finnish cohort study". Stroke 45(10): E210-E210

Letter by Kleemann and Seidl regarding article, "Necessity for surgical revision of defibrillator leads implanted long-term: causes and management". Circulation 119(1): E8; Author Reply E9-E8; Author Reply E9

Letter by Klein regarding article, "Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study". Circulation 117(4): E21; Author Reply E22-E21; Author Reply E22

Letter by Knight et al regarding article, "Validation of in vivo magnetic resonance imaging blood-brain barrier permeability measurements by comparison with gold standard histology". Stroke 42(10): E568-E568

Letter by Knop regarding article, "Effect of torcetrapib on glucose, insulin, and hemoglobin A1c in subjects in the investigation of lipid level management to understand its impact in atherosclerotic events (ILLUMINATE) trial". Circulation 125(9): E428-E428

Letter by Koh and Quon regarding article, "Evidence mandating earlier and more aggressive treatment of hypercholesterolemia". Circulation 119(12): E376; Author Reply E377-E376; Author Reply E377

Letter by Koh regarding article, "Statins and risk of new-onset diabetes mellitus". Circulation 127(23): E837-E837

Letter by Kohl regarding article, "Current status of fetal cardiac intervention". Circulation 122(18): E506-E506

Letter by Kono regarding article, "Plasma bilirubin and UGT1A1*28 are not protective factors against first-time myocardial infarction in a prospective, nested case-referent setting". Circulation. Cardiovascular Genetics 4(1): E1; Author Reply E2-E1; Author Reply E2

Letter by Kordalis et al regarding article, "ECG response: May 20, 2014". Circulation 130(14): E127-E127

Letter by Korn-Lubetzki regarding article, "Onset headache predicts good outcome in patients with first-ever ischemic stroke". Stroke 44(10): E132-E132

Letter by Korosoglou et al regarding article, "Association between high-sensitivity C-reactive protein and coronary plaque subtypes assessed by 64-slice coronary computed tomography angiography in an asymptomatic population". Circulation. Cardiovascular Imaging 4(5): E26-E26

Letter by Kosiuk et al regarding article, "implication of left ventricular diastolic dysfunction in cryptogenic ischemic stroke". Stroke 45(11): E234-E234

Letter by Kothari regarding article, "Rheumatic heart disease screening by echocardiography: The inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease". Circulation 121(21): E420; Author Reply E423-E420; Author Reply E423

Letter by Kounis et al regarding article, "sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy". Circulation Journal 72(10): 1721; Author Reply 1722-1721; Author Reply 1722

Letter by Kovacs regarding article, "Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association". Stroke 42(7): E408-E408

Letter by Kriatselis and Roser regarding article, "Small or large isolation areas around the pulmonary veins for the treatment of atrial fibrillation? Results from a prospective randomized study". Circulation 116(25): E575; Author Reply E576-E575; Author Reply E576

Letter by Krijnen et al regarding article, "The sPLA2 Inhibition to Decrease Enzyme Release after Percutaneous Coronary Intervention (SPIDER-PCI) trial". Circulation 124(11): E298; Author Reply E299-300

Letter by Krötz et al regarding article, "Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure" . Circulation 115(25): E648; Author Reply E649-E648; Author Reply E649

Letter by Kuller and Mackey regarding article, "Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection study". Circulation 126(20): E321-E321

Letter by Kuller and Wong regarding article, "comparative effectiveness of exercise electrocardiography with or without myocardial perfusion single photon emission computed tomography in women with suspected coronary artery disease: results from the What Is the Optimal Method for Ischemia Evaluation in Women (WOMEN) trial". Circulation 125(19): E931; Author Reply E932-5

Letter by Kumar and Kounis regarding article, "coronary artery spasm: a 2009 update". Circulation 121(3): E15; Author Reply E19-E15; Author Reply E19

Letter by Kurnik et al regarding article, "antithrombotic therapy and bleeding risk in a prospective cohort study of patients with cerebral cavernous malformations". Stroke 44(5): E52-E52

Letter by Kurtoglu et al regarding article, "Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke". Stroke 44(12): E229-E229

Letter by Kutlubaev and Mead regarding article, "Exertion fatigue and chronic fatigue are two distinct constructs in people post-stroke". Stroke 42(5): E377-E377

Letter by Labovitz and Bhupali regarding article, "transient ischemic attack in Joinville, Brazil, 2010: a population-based study". Stroke 43(6): E55; Author Reply E56-E55; Author Reply E56

Letter by Lacout et Al regarding article, "prevalence, characteristics, and outcomes of patients presenting with cardiogenic unilateral pulmonary edema". Circulation 123(20): E607; Author Reply E608-E607; Author Reply E608

Letter by Lagro et al regarding article, "Nationwide cohort study of risk of ischemic heart disease in patients with celiac disease". Circulation 124(16): E422; Author Reply E423-E422; Author Reply E423

Letter by Lagro et al regarding article, "Treatment of unexplained syncope: a multicenter, randomized trial of cardiac pacing guided by adenosine 5'-triphosphate testing". Circulation 126(8): E121-E121

Letter by Lagro et al regarding article, "average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people". Circulation 125(23): E1016; Author Reply E1018-E1016; Author Reply E1018

Letter by Lahr et al regarding article, "Promoting thrombolysis in acute ischemic stroke". Stroke 42(7): E411-E411

Letter by Lai and Chan regarding article, "Bleeding risk in very old patients on vitamin K antagonist treatment: results of a prospective collaborative study on elderly patients followed by Italian Centres for Anticoagulation". Circulation 125(11): E493; Author Reply E494-E493; Author Reply E494

Letter by Lambertucci and Antunes regarding article, "pulmonary vascular disease in the developing world". Circulation 120(1): E6; Author Reply E7-E6; Author Reply E7

Letter by Lancaster et al regarding article, "Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure". Circulation 120(7): E48-E48

Letter by Landa et al regarding article, "Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function". Circulation 121(21): E419-E419

Letter by Landis et al regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients". Circulation 117(22): E473; Author Reply E476-E473; Author Reply E476

Letter by Langhorne and Stott regarding article, "Very early mobilization after stroke fast-tracks return to walking: further results from the phase II AVERT randomized controlled trial". Stroke 42(5): E376-E376

Letter by Lanterna et al regarding article, "endovascular treatment of intracranial aneurysms with flow-diverters, a meta-analysis". Stroke 44(5): E54-E54

Letter by Laskey regarding article, "systemic hypertension in low-gradient severe aortic stenosis with preserved ejection fraction". Circulation 130(1): E4-E4

Letter by Lauten et al regarding article, "Interventional cardiology perspective of functional tricuspid regurgitation". Circulation. Cardiovascular Interventions 3(3): E10; Author Reply E11-E10; Author Reply E11

Letter by Layland et al regarding article, "Validation of intravascular ultrasound-derived parameters with fractional flow reserve for assessment of coronary stenosis severity". Circulation. Cardiovascular Interventions 4(3): E16; Author Reply E17-E16; Author Reply E17

Letter by Lecoultre and Tam regarding article, "Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation". Circulation 125(4): E315; Author Reply E316-E315; Author Reply E316

Letter by Lederer and Wiedermann regarding article, "effectiveness of bystander-initiated cardiac-only resuscitation for patients with out-of-hospital cardiac arrest". Circulation 117(25): E508; Author Reply E509-E508; Author Reply E509

Letter by Lederman et al regarding article, "MRI-induced stent dislodgment soon after left main coronary artery stenting". Circulation. Cardiovascular Interventions 7(1): 128-128

Letter by Lee and Goldman regarding article, "Development and validation of a risk calculator for prediction of cardiac risk after surgery". Circulation 125(7): E385; Author Reply E386-E385; Author Reply E386

Letter by Lee et al regarding article, "Spontaneous resolution of central serous chorioretinopathy in a patient with congenital retinal macrovessel". Circulation 126(2): E24-E24

Letter by Lee et al regarding article, "training of future interventional neuroradiologists: the European approach". Stroke 44(5): E46-E46

Letter by Lee regarding article, "CC chemokine receptor-1 activates intimal smooth muscle-like cells in graft arterial disease". Circulation 121(23): E437; Author Reply E438-E437; Author Reply E438

Letter by Lee regarding article, "Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute stroke". Stroke 42(10): E566; Author Reply E567-E566; Author Reply E567

Letter by Lee regarding article, "Multi-analyte profiling reveals MMP-9 and MPC-1 as plasma biomarkers of cardiac aging". Circulation. Cardiovascular Genetics 4(6): E30; Author Reply E31-E30; Author Reply E31

Letter by Legge et al regarding article, "Safety of intravenous fibrinolysis in imaging-confirmed single penetrator artery infarcts". Stroke 42(4): E363; Author Reply E364-E363; Author Reply E364

Letter by Lema et al regarding article, "Renal vasodilatory action of dopamine in patients with heart failure: magnitude of effect and site of action". Circulation 118(17): E675; Author Reply E676-E675; Author Reply E676

Letter by Lensen et al regarding article, "anti-tumor necrosis factor-α therapy reduces aortic inflammation and stiffness in patients with rheumatoid arthritis". Circulation 128(1): E10-E10

Letter by Leurent et al regarding article, "Prevalence and clinical significance of papillary muscle infarction detected by late gadolinium-enhanced magnetic resonance imaging in patients with ST-segment elevation myocardial infarction". Circulation 124(1): E19; Author Reply E20-E19; Author Reply E20

Letter by Li and Shen regarding article, "growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery". Circulation 130(13): E117-E117

Letter by Li and Yu regarding article, "ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity". Circulation 130(8): E71-E71

Letter by Liao et al regarding article, "socioeconomic status inconsistency and risk of stroke among Japanese middle-aged women". Stroke 45(11): E233-E233

Letter by Lin et al regarding article, "Acute kidney injury and cardiovascular outcomes in acute severe hypertension". Circulation 123(9): E267; Author Reply E268-E267; Author Reply E268

Letter by Lin et al regarding article, "Dabigatran and thrombin modulate electrophysiological characteristics of pulmonary vein and left atrium" by Chang et al. Circulation. Arrhythmia and Electrophysiology 6(2): E22-E22

Letter by Lin et al regarding article, "Heart rate predicts outcomes in an implantable cardioverter-defibrillator population". Circulation 121(24): E450; Author Reply E452-E450; Author Reply E452

Letter by Lin et al regarding article, "Hepatitis C virus infection and increased risk of cerebrovascular disease". Stroke 42(6): E389; Author Reply E390-1

Letter by Lin et al regarding article, "Nitric oxide scavenging of red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion". Circulation 125(7): E384-E384

Letter by Lin et al regarding article, "Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention". Circulation 121(7): E43; Author Reply E44-5

Letter by Lin et al regarding article, "does body mass index impact on the relationship between systolic blood pressure and cardiovascular disease? Meta-analysis of 419 488 individuals from the Asia pacific cohort studies collaboration". Stroke 43(10): E105; Author Reply E106-E105; Author Reply E106

Letter by Lippi and Cervellin regarding article, "High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease". Circulation 127(3): E353-E353

Letter by Lippi and Cervellin regarding article, "High-sensitivity troponin T concentrations in acute chest pain patients evaluated with cardiac computed tomography". Circulation 123(1): E3; Author Reply E4-E3; Author Reply E4

Letter by Liu et al regarding article, "rosiglitazone and outcomes for patients with diabetes mellitus and coronary artery disease in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial". Circulation 129(16): E459-E459

Letter by Llau and Ferrandis regarding article, "Bridging evidence-based practice and practice-based evidence in periprocedural anticoagulation". Circulation 127(19): E616-E616

Letter by Lopez-Messa and Alonso-Fernandez regarding article, "Temporal differences in out-of-hospital cardiac arrest (OHCA): incidence and survival". Circulation 130(9): E82-E82

Letter by Lotz et al regarding article, "Reactive oxygen species-induced stimulation of 5' AMP-activated protein kinase mediates sevoflurane-induced cardioprotection". Circulation 121(18): E399; Author Reply E400-E399; Author Reply E400

Letter by Lowenthal et al regarding article, "BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial". Circulation. Heart Failure 3(6): E32; Author Reply E33-E32; Author Reply E33

Letter by Lown et al regarding article, "Risk of assessing mortality risk in elective cardiac operations: age, creatinine, ejection fraction, and the law of parsimony". Circulation 121(8): E225; Author Reply E227-E228

Letter by Lozano et al regarding article "previous coronary stent implantation and cardiac events in patients undergoing noncardiac surgery". Circulation. Cardiovascular Interventions 3(4): E16; Author Reply E17-E16; Author Reply E17

Letter by Lozano et al regarding article, "Adjunctive thrombectomy for acute myocardial infarction: a bayesian meta-analysis". Circulation. Cardiovascular Interventions 3(3): E8; Author Reply E9-E8; Author Reply E9

Letter by Lozano et al regarding article, "Increased risk of bleeding in patients on clopidogrel therapy after drug-eluting stents implantation: insights from the HMO Research Network-Stent Registry (HMORN-stent)". Circulation. Cardiovascular Interventions 3(5): E24; Author Reply E25-E24; Author Reply E25

Letter by Lozano et al regarding articles, "transcatheter valve-in-valve implantation for failed bioprosthetic heart valves" and "percutaneous therapy for valvular heart disease: a huge advance and a huge challenge to do it right". Circulation 123(3): E15-E15

Letter by Lucchetti and Granero regarding article, "Optimism, cynical hostility, and incident coronary heart disease and mortality in the women's health initiative". Circulation 121(19): E407; Author Reply E408-E407; Author Reply E408

Letter by Luermans et al regarding article, "Lack of association between migraine headache and patent foramen ovale: results of a case-control study". Circulation 122(24): E582; Author Reply E583-E582; Author Reply E583

Letter by Lumley et al regarding article, "arterial pulse wave dynamics after percutaneous aortic valve replacement: fall in coronary diastolic suction with increasing heart rate as a basis for angina symptoms in aortic stenosis". Circulation 125(16): E612; Author Reply E613-E612; Author Reply E613

Letter by Lund et al regarding article, "fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events". Circulation 119(13): E384; Author Reply E385-E384; Author Reply E385

Letter by Ly regarding article, "Direct intramyocardial but not intracoronary injection of bone marrow cells induces ventricular arrhythmias in a rat chronic ischemic heart failure model". Circulation 116(23): E554; Author Reply 555-E554; Author Reply 555

Letter by Ma et al regarding article, "Ischemic postconditioning during primary percutaneous coronary intervention: the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction (POST) randomized trial". Circulation 130(6): E52-E52

Letter by Maarsingh and van der Wouden regarding article, "Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department". Stroke 43(8): E78; Author Reply E79-E78; Author Reply E79

Letter by Maass and Maier regarding article, "Cardiac arrhythmogenic remodeling in a rat model of long-term intensive exercise training". Circulation 124(9): E249; Author Reply E251-E249; Author Reply E251

Letter by MacDonald et al regarding article, "Catheter ablation of atrial fibrillation". Circulation 127(4): E433-E433

Letter by Madeddu regarding article, "Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis". Circulation 122(22): E565; Author Reply E567-E565; Author Reply E567

Letter by Madias regarding article, "Crescendo in depolarization and repolarization heterogeneity heralds development of ventricular tachycardia in hospitalized patients with decompensated heart failure". Circulation. Arrhythmia and Electrophysiology 5(3): E78; Author Reply E79-E78; Author Reply E79

Letter by Madias regarding article, "Relationship between nonsustained ventricular tachycardia after non-ST-elevation acute coronary syndrome and sudden cardiac death: observations from the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial". Circulation 123(14): E403; Author Reply E405-E403; Author Reply E405

Letter by Madias regarding article, "Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy". Circulation 120(3): E21; Author Reply E22-E21; Author Reply E22

Letter by Madias regarding article, "peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling". Circulation 121(16): E388; Author Response E389-E388; Author Response E389

Letter by Madias regarding the article, "Repolarization alternans reveals vulnerability to human atrial fibrillation". Circulation 125(4): E320; Author Reply E321-E320; Author Reply E321

Letter by Magalhaes et al regarding article, "Long-term survival and repeat coronary revascularization in dialysis patients after surgical and percutaneous coronary revascularization with drug-eluting and bare metal stents in the United States". Circulation 128(20): E406-E406

Letter by Mahajan regarding article, "a narrow QRS complex tachycardia with apparently concentric retrograde atrial activation sequence". Indian Pacing and Electrophysiology Journal 9(4): 213-213

Letter by Maier et al regarding article, "Emergency department bypass for ST-segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline Program". Circulation 129(9): E371-E371

Letter by Maini regarding article, "percutaneous left-ventricular support with the impella-2.5-assist device in acute cardiogenic shock: results of the impella-EUROSHOCK-registry". Circulation. Heart Failure 6(4): E55-E55

Letter by Makkar et al regarding article, "Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions". Circulation Research 115(11): E32-E32

Letter by Makris et al regarding article, "Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes". Stroke 42(6): E397; Author Reply E398-E397; Author Reply E398

Letter by Malavazos et al regarding article, "sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men". Circulation 126(17): E274; Author Reply E275-E274; Author Reply E275

Letter by Malyar et al regarding article, "supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) study". Circulation 126(7): E101; Author Reply E102-3

Letter by Mamkin et al regarding article, "weekend onset of acute myocardial infarction does not have a negative impact on outcome in Japan". Circulation Journal 72(5): 864; Author Reply 865-864; Author Reply 865

Letter by Mangiacapra and Barbato regarding article, "Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease". Circulation. Cardiovascular Interventions 6(5): E65-E65

Letter by Mao et al regarding article, "Noninvasive fractional flow reserve derived from computed tomography angiography for coronary lesions of intermediate stenosis severity: results from the DeFACTO study". Circulation. Cardiovascular Imaging 7(3): 570-570

Letter by Marcadenti and Oliveira de Abreu Silva regarding article, "Chocolate intake and incidence of heart failure: a population-based, prospective study of middle-aged and elderly women". Circulation. Heart Failure 4(1): E5; Author Reply E6-E5; Author Reply E6

Letter by Marijon regarding article, "Perinatal outcome of fetal atrioventricular block: one-hundred sixteen cases from a single institution". Circulation 119(20): E540; Author Reply E541-2

Letter by Mark et al regarding article, "Implementation of the fifth link of the chain of survival concept for out-of-hospital cardiac arrest". Circulation 127(16): E566-E566

Letter by Markl and Harloff regarding article, "Aortic arch plaques and risk of recurrent stroke and death". Circulation 121(2): E11; Author Reply E12-E11; Author Reply E12

Letter by Markl and Harloff regarding article, "Right-left propensity and lesion patterns between cardiogenic and aortogenic cerebral embolisms". Stroke 42(10): E562-E562

Letter by Marlu et al regarding article, "reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects". Circulation 125(16): E615; Author Reply E616-E615; Author Reply E616

Letter by Marques and Morris regarding article, "Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection". Circulation 125(5): E337; Author Reply E338-9

Letter by Martin and Jenni regarding article, "Limitations of Doppler echocardiography in the evaluation of serial stenoses". Circulation. Cardiovascular Imaging 7(1): 211-211

Letter by Martinez-Selles regarding article, "Risk of acute myocardial infarction after the death of a significant person in one's life: the Determinants of Myocardial Infarction Onset Study". Circulation 126(3): E36; Author Reply E37-E36; Author Reply E37

Letter by Martínez-Martínez et al regarding article, "variable presentations of postpartum angiopathy" . Stroke 43(6): E57; Author Reply E58-E57; Author Reply E58

Letter by Marín et al regarding article, "Bleeding after initiation of multiple antithrombotic drugs, including triple therapy, in atrial fibrillation patients following myocardial infarction and coronary intervention: a nationwide cohort study". Circulation 127(17): E584-E584

Letter by Mascitelli and Goldstein regarding article, "cardiovascular events as a function of serum bilirubin levels in a large, statin-treated cohort". Circulation 127(24): E860-E860

Letter by Mascitelli et al regarding ethnic differences in carotid intima-media thickness between UK children of black African-Caribbeans and white Europeans. Stroke 43(10): E103; Author Reply E104-E103; Author Reply E104

Letter by Maurizia Grasso et al. regarding article, "Restrictive cardiomyopathy with atrioventricular conduction block resulting from a desmin mutation". International Journal of Cardiology 131(1): 144-5; Author Reply 146-7

Letter by May et al regarding article, "Use of dabigatran for periprocedural anticoagulation in patients undergoing catheter ablation for atrial fibrillation" by Bassiouny et al. Circulation. Arrhythmia and Electrophysiology 6(4): E65-E65

Letter by Maytin and Epstein et al regarding article, "Complications associated with revision of Sprint Fidelis leads: report from the Canadian Heart Rhythm Society Device Advisory Committee". Circulation 123(10): E375-E375

Letter by Mc Loughlin and Mc Loughlin regarding article, "sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men". Circulation 126(17): E273; Author Reply E275-E273; Author Reply E275

Letter by McAuley et al regarding article, "Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men". Circulation 122(11): E455; Author Reply E457-E455; Author Reply E457

Letter by McColl et al regarding article, "influenza virus infection aggravates stroke outcome". Stroke 42(8): E416; Author Reply E417-E416; Author Reply E417

Letter by McEvoy regarding article, "Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both". Circulation 123(18): E585; Author Reply E586-7

Letter by McGuire and Aguilar regarding article, "Effect of torcetrapib on glucose, insulin, and hemoglobin A1c in subjects in the investigation of lipid level management to understand its impact in atherosclerotic events (ILLUMINATE) trial". Circulation 125(9): E427-E427

Letter by McLachlan et al regarding article, "Cough cardiopulmonary resuscitation revisited". Circulation 115(19): E460; Author Reply E461-E460; Author Reply E461

Letter by Mead et al regarding article, "Selective serotonin reuptake inhibitors for stroke: more trials are needed". Stroke 44(4): E40-E41

Letter by Mehran et al regarding article, "Bleeding academic research consortium consensus report: the food and drug administration perspective". Circulation 125(10): E460-E460

Letter by Mehta Oza and Raman regarding article, "Ischemic preconditioning for prevention of contrast medium-induced nephropathy: randomized pilot RenPro Trial (Renal Protection Trial)". Circulation 127(13): E535-E535

Letter by Meier and Seiler regarding article, "Impact of collateral flow to the occluded infarct-related artery on clinical outcomes in patients with recent myocardial infarction: a report from the randomized occluded artery trial". Circulation 123(8): E255; Author Reply E257-8

Letter by Melandri regarding article, "A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction". Circulation 117(18): E328; Author Reply E329-E328; Author Reply E329

Letter by Messas et al regarding article, "Initial results of posterior leaflet extension for severe type IIIb ischemic mitral regurgitation". Circulation 121(6): E36-E36

Letter by Metzler et al regarding article, "Intracoronary KAI-9803 as an adjunct to primary coronary intervention for acute ST-segment elevation myocardial infarction". Circulation 118(4): E80-E80

Letter by Meurin et al regarding article, "Early surgery versus conventional treatment in asymptomatic very severe aortic stenosis". Circulation 122(25): E638; Author Reply E639-E638; Author Reply E639

Letter by Meves and Neubauer regarding article "Clinical outcomes using a platelet function-guided approach for secondary prevention in patients with ischemic stroke or transient ischemic attack". Stroke 43(11): E167; Author Reply E168-E167; Author Reply E168

Letter by Mezzaroma, et al regarding article, "NLRP3 inflammasome as a therapeutic target in myocardial infarction". International Heart Journal 55(4): 379-379

Letter by Miceli et al regarding article, "No major differences in 30-day outcomes in high-risk patients randomized to off-pump versus on-pump coronary bypass surgery: the Best Bypass Surgery Trial". Circulation 122(17): E497; Author Reply E499-E497; Author Reply E499

Letter by Miceli et al regarding article, "Risk of assessing mortality risk in elective cardiac operations: age, creatinine, ejection fraction, and the law of parsimony". Circulation 121(8): E226; Author Reply E227-E228

Letter by Micheletti and Chevallier regarding article, "Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER Study". Circulation 116(13): E362; Author Reply E363-E362; Author Reply E363

Letter by Michiels et al regarding article, "Diagnostic accuracy of combined intracoronary pressure and flow velocity information during baseline conditions: adenosine-free assessment of functional coronary lesion severity". Circulation. Cardiovascular Interventions 5(6): E84; Author Reply E86-7

Letter by Minciu Macrea et al regarding article, "Leptin signaling in the failing and mechanically unloaded human heart". Circulation. Heart Failure 3(3): E12; Author Reply E16-E12; Author Reply E16

Letter by Minutoli et al regarding article, "Reduced myocardial 123-iodine meta-iodobenzylguanidine uptake: a prognostic marker in familial amyloid polyneuropathy". Circulation. Cardiovascular Imaging 6(6): E76-E76

Letter by Misra et al regarding article, "anticoagulants for cerebral venous thrombosis: harmful to patients?". Stroke 45(6): E110-E110

Letter by Mittal and McCormick regarding article, "self-report of stroke, transient ischemic attack, or stroke symptoms and risk of future stroke in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study". Stroke 44(5): E53-E53

Letter by Moccia et al regarding article, "Archetypal Arg169Cys mutation in NOTCH3 does not drive the pathogenesis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy via a loss-of-function mechanism". Stroke 45(7): E128-E128

Letter by Modarai et al regarding article, "Contemporary analysis of descending thoracic and thoracoabdominal aneurysm repair". Circulation 120(11): E89-E89

Letter by Mokhles et al regarding article, "Prosthetic heart valve". Circulation 124(24): E897; Author Reply E898-E897; Author Reply E898

Letter by Molkentin regarding article, "The absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit Locus". Circulation Research 115(8): E21-E23

Letter by Moll regarding article, "Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran". Stroke 43(2): E24; Author Reply E25-E24; Author Reply E25

Letter by Mont et al regarding article, "Physical activity and incidence of atrial fibrillation in older adults: the Cardiovascular Health Study". Circulation 119(5): E195; Author Reply E196-E195; Author Reply E196

Letter by Montani et al regarding article, "Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension". Circulation 123(21): E614; Author Reply E615-E614; Author Reply E615

Letter by Montenegro and Lundberg regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". Circulation 129(13): E426-E426

Letter by Montone et al regarding article, "Atrial fibrillation: outpatient presentation and management". Circulation 125(4): E318; Author Reply E319-E318; Author Reply E319

Letter by Moody et al regarding article "Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction". Circulation 126(5): E62; Author Reply E64-5

Letter by Morel et al regarding article, "Ischemic postconditioning during primary percutaneous coronary intervention: the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction (POST) randomized trial. Circulation 130(6): E53-E53

Letter by Morikawa et al regarding article, "coronary artery spasm: a 2009 update". Circulation 121(3): E16; Author Reply E19-E16; Author Reply E19

Letter by Morris et al regarding article, "Low heart rates predict incident atrial fibrillation in healthy middle-aged men" by Grundvold et al. Circulation. Arrhythmia and Electrophysiology 6(6): E101-E101

Letter by Movahed regarding article, "Randomized Study of the Crush Technique Versus Provisional Side-Branch Stenting in True Coronary Bifurcations: The CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study". Circulation 120(8): E63; Author Reply E64-E63; Author Reply E64

Letter by Movahed regarding article, "Simple or complex stenting for bifurcation coronary lesions: a patient-level pooled analysis of the Nordic Bifurcation Study and the British Bifurcation Coronary Study". Circulation. Cardiovascular Interventions 4(3): E20-E20

Letter by Mugikura and Takahashi regarding article, "Perfusion characteristics of moyamoya disease: an anatomically and clinically oriented analysis and comparison". Stroke 45(3): E48-E48

Letter by Munin et al regarding article, "Botulinum Toxin for the Upper Limb after Stroke (BoTULS) trial: effect on impairment, activity limitation, and pain". Stroke 42(7): E412; Author Reply E413-E412; Author Reply E413

Letter by Munoz Arrondo et al regarding article, "Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis". Stroke 42(12): E638-E638

Letter by Murakami and Niwa regarding article, "Unknown complication of arterial switch operation: resistant hypertension induced by a strong aortic arch angulation". Circulation 130(11): E100-E100

Letter by Murphy et al regarding article, "Fugl-Meyer assessment of sensorimotor function after stroke: standardized training procedure for clinical practice and clinical trials". Stroke 42(6): E402-E402

Letter by Murry et al regarding article, "Embryonic stem cell-derived cardiac myocytes are not ready for human trials". Circulation Research 115(10): E28-E29

Letter by Murzi and Glauber regarding article, "Extensive primary repair of the thoracic aorta in acute type A aortic dissection by means of ascending aorta replacement combined with open placement of triple-branched stent graft: early results". Circulation 123(22): E619; Author Reply E620-E619; Author Reply E620

Letter by Nabi regarding article, "attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries". Circulation 123(20): E605; Author Reply E606-E605; Author Reply E606

Letter by Naeije and Melot regarding article, "Exercise-induced pulmonary arterial hypertension". Circulation 120(23): E283; Author Reply E284-E283; Author Reply E284

Letter by Nagelkerke and Conca regarding article, "acute coronary syndrome and khat herbal amphetamine use: an observational report". Circulation 126(6): E86; Author Reply E87-8

Letter by Naggara et al regarding article, "Are distal protection devices 'protective' during carotid angioplasty and stenting?". Stroke 42(11): E578-80; Author Reply E581

Letter by Nagueh et al regarding article, "Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure". Circulation 120(7): E44-E44

Letter by Naimer regarding article, "Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study". Circulation 124(21): E552; Author Reply E555-E552; Author Reply E555

Letter by Nakajima and Saito regarding article, "Human C-reactive protein does not promote atherosclerosis in transgenic rabbits". Circulation 122(4): E406; Author Reply E407-E406; Author Reply E407

Letter by Nakano et Al regarding article, "optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation". Circulation 124(25): E954; Author Reply E955-E954; Author Reply E955