+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Long-term survival after hospitalization for acute heart failure--differences in prognosis of acutely decompensated chronic and new-onset acute heart failure

, : Long-term survival after hospitalization for acute heart failure--differences in prognosis of acutely decompensated chronic and new-onset acute heart failure. International Journal of Cardiology 168(1): 458-462

To analyze the five-year mortality after hospitalization for acute heart failure (AHF) and compare predictors of prognosis in patients with and without a previous history of heart failure. Patients with AHF (n=620) from the prospective multicenter FINN-AKVA study were classified as acutely decompensated chronic heart failure (ADCHF) or de-novo AHF if no previous history of heart failure was present. Both all-cause mortality during five years of follow-up and prognostic factors were determined. The overall mortality was 60.3% (n=374) at five years. ADCHF was associated with significantly poorer outcome compared to de-novo AHF; five-year mortality rate 75.6% vs. 44.4% (p<0.001). Initially, mortality was high (33.5% in ADCHF and 21.7% in de-novo AHF after 12 months), but in de-novo AHF the annual mortality declined markedly already after the first year. Compared to de-novo AHF, patients with ADCHF had an increased risk of death for several years after the index hospitalization. A previous history of heart failure was an independent predictor of five-year mortality (adjusted hazard ratio 1.8 (95% CI 1.4-2.2; p<0.001). Older age and impaired renal function were associated with adverse long-term prognosis in both ADCHF and de-novo AHF, while higher systolic blood pressure on admission predicted better outcome. The long-term prognosis after hospitalization for AHF is poor, with a significantly different survival observed in patients with de-novo AHF compared to ADCHF. A previous history of heart failure is an independent predictor of five-year mortality. Distinction between ADCHF and de-novo AHF may improve our understanding of patients with AHF.


PMID: 23073273

DOI: 10.1016/j.ijcard.2012.09.128

Other references

Ledvinkova Vlasta; Waldhausrova Jarmila; Palivcova Marie, 1999: Recrystallized members of upper Proterozoic ultramafic magmatism in the Variscan felsic/ mafic stratified plutonic series in the Teletin quarries (central Bohemian Pluton, Bohemian Massif). The mafic up to ultramafic rock, uralitic metagabbro of the Variscan stratified mafic/felsic calc-alkaline suite in the Teletin area is described. The metagabbro occurs as a sill at the bottom of the stratified sequence and as a megaenclave in a z...

Zhu, J.J.lius; Sakmann, B., 1998: Whisker-evoked slow oscillation in single neurons of the rat barrel cortex. Society for Neuroscience Abstracts 24(1-2): 1512

Tarzaali, A.; Viens, P.; Quevillon, M., 1972: Immunodepression after whooping cough vaccination in mice infected with Plasmodium berghei yoelii. Mice were infected intraperitoneally with 4 X 105 Plasmodium berghei yoelii, and 7 or 13 days later they were inoculated with whooping cough vaccine in dilutions corresponding to doses of 85, 50 or 15% protection. Antibody titres (measured by aggl...

Khaw, O.K., 1930: Prosthogonimus. China Medical Journal, 44: 922-923

Blue J.H.; Ross S., 1982: Spatial discrimination learning by young rats. Twenty hooded rat pups were tested at 17 days of age on a left-right spatial discrimination task. One experiment used homing as the incentive (n = 10), and the other experiment used suckling as the incentive (n = 10). Each rat was given a maximum...

Locock A.J.; Burns P.C., 2002: The crystal structures of uranyl phosphate and uranyl arsenate minerals. Abstracts of the : eral Meeting of the International Mineralogical Association. 18; Pages 118. 2002.

Bailey, H.C.; Deanovic, L.; Reyes, E.; Kimball, T.; Larson, K.; Cortright, K.; Connor, V.; Hinton, D.E., 2000: Diazinon and chlorpyrifos in urban waterways in Northern California, USA. Samples collected from urban streams in the cities of Sacramento and Stockton, California, USA, during the precipitation season were analyzed for diazinon and chlorpyrifos. Concentrations were determined with enzyme-linked immunosorbent assays spe...

Fritel, P.H., 1910: Les Eohinodermes fossiles. Naturaliste Paris : 32 149-161

Freeman, C.E.; Reid, W.H.; Becvar, J.E., 1983: Nectar sugar composition in some species of Agave (Agavaceae). The nectar sugar composition of 19 Agave species, determined by HPLC, varied among the species; 11 produced hexose-rich nectars with small amounts of sucrose, 4 produced nectars that contained hexoses only, and 4 produced sucrose-rich nectars. Kno...

Martín, J.; Pérez-Gil, J.; Acebal, C.; Arche, R., 1990: Theoretical approach to the steady-state kinetics of a bi-substrate acyl-transfer enzyme reaction that follows a hydrolysable-acyl-enzyme-based mechanism. Application to the study of lysophosphatidylcholine:lysophosphatidylcholine acyltransferase from rabbit lung. A kinetic model is proposed for catalysis by an enzyme that has several special characteristics: (i) it catalyses an acyl-transfer bi-substrate reaction between two identical molecules of substrate, (ii) the substrate is an amphiphilic molecule th...