+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Lymphatic mapping in patients with primary or recurrent breast cancer following previous axillary surgery

, : Lymphatic mapping in patients with primary or recurrent breast cancer following previous axillary surgery. European Journal of Surgical Oncology 34(8): 851-856

To evaluate the feasibility of lymphatic mapping in breast cancer patients after previous axillary surgery and to identify parameters associated with mapping failure. Lymphatic mapping using peritumoural injection of blue dye and a radiocolloid was attempted in 30 patients with primary (n=7) or recurrent (n=23) breast cancer and a history of previous axillary lymph node dissection or sentinel node biopsy. Lymphatic mapping identified a mean number of 1.6 (range 1-3) lymph nodes in 19 of 30 patients (identification rate 63%). The lymph nodes were removed from the ipsilateral axilla (n=13), the internal mammary chain (n=2), both the internal mammary nodes and the axilla (n=2), the interpectoral space (n=1) and the contralateral axilla (n=1). Four of 19 patients revealed a positive lymph node. Fifteen of 19 patients had a negative lymph node. Axillary lymph node dissection was done in 13 of 15 patients but found no positive nodes (false negative rate=0). A negative lymphoscintigram (p<0.001) and a number of more than 10 lymph nodes removed at the time of initial surgery (p=0.02) were significantly associated with a mapping failure. Lymphatic mapping following prior axillary surgery was accurate but associated with a low identification rate. The lymphatic drainage pattern was unpredictable and the use of a radionuclide was necessary for a successful mapping procedure.


PMID: 18162358

DOI: 10.1016/j.ejso.2007.11.006

Other references

Cui, S.; Christensen, E.I., 1993: Three-dimensional organization of the vacuolar apparatus involved in endocytosis and membrane recycling of rat kidney proximal tubule cells. An electron-microscopic study of serial sections. The present study was performed to examine the three-dimensional structure of the vacuolar apparatus involved in endocytosis and especially the membrane recycling pathway of rat renal proximal tubule cells by electron microscopy of serial sections...

Shabanova, E.; Inshakova, T.; Bishlyaga, V.; Sergeeva, L., 1978: Substrate specificity of Pseudomonas fluorescens lipase. Applied biochemistry and microbiology 14(3): 359-364

Sutherland Donald G., 1991: Late Devensian glacial deposits and glaciation in Scotland and the adjacent offshore region. Pages 53-59 1991

Lauson, H.D., 1965: Antidiuretic Hormone. Federation Proceedings 24: 731-736

Cardinal, R., 2009: Outsider Art and the autistic creator. Outsider Art (art brut) is defined as a mode of original artistic expression which thrives on its independence, shunning the public sphere and the art market. Such art can be highly idiosyncratic and secretive, and reflects the individual creator&...

Manouras, A.; Markogiannakis, H.; Genetzakis, M.; Filippakis, G.M.; Lagoudianakis, E.E.; Kafiri, G.; Filis, K.; Zografos, G.C., 2008: Modified radical mastectomy with axillary dissection using the electrothermal bipolar vessel sealing system. The use of the electrothermal bipolar vessel sealing system is feasible, safe, and effective in modified radical mastectomy with axillary dissection in terms of lymph vessel sealing, hemostasis, and perioperative complications. Prospective study....

Yokoyama, K.; Araki, S.; Murata, K.; Morita, Y.; Katsuno, N.; Tanigawa, T.; Mori, N.; Yokota, J.; Ito, A.; Sakata, E., 1997: Subclinical vestibulo-cerebellar, anterior cerebellar lobe and spinocerebellar effects in lead workers in relation to concurrent and past exposure. By computerized static posturography, the subclinical effects of past and concurrent lead absorption on the vestibulo-cerebellum (lower vermis), anterior cerebellar lobe and spinocerebellar afferent pathway were examined in 49 male chemical factor...

Storch, M.J.ergen; Marbach, P.; Kerp, L., 1993: A time-resolved fluoroimmunoassay for human insulin based on two monoclonal antibodies. The insulin time-resolved fluoroimmunoassay (TRFIA) described here is a 'sandwich type' immunoassay using two monoclonal antibodies recognizing different epitopes of insulin. One of the antibodies is fixed to a solid phase and the other...

Gaykema, R.P.; Goehler, L.E.; Tilders, F.J.; Bol, J.G.; McGorry, M.; Fleshner, M.; Maier, S.F.; Watkins, L.R., 1998: Bacterial endotoxin induces fos immunoreactivity in primary afferent neurons of the vagus nerve. Subdiaphragmatic vagotomy inhibits brain-mediated illness responses to peripherally administered bacterial endotoxin, including fever, hyperalgesia, sickness behavior, and activation of the hypothalamic-pituitary-adrenal axis. However, direct evid...

Raible A.; Plauth M.; Bauder Gross D.; Vieillard Baron D.; Hartmann F., 1992: Effects of endotoxin on glutamine metabolism in the isolated perfused rat small intestine and cell cultures of isolated enterocytes. Gastroenterology 102(4 PART 2): A573