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Malaria associated acute renal failure--experience from Rourkela, eastern India


, : Malaria associated acute renal failure--experience from Rourkela, eastern India. Journal of the Indian Medical Association 106(10): 640-2, 654

Acute renal failure is a significant complication of falciparum malaria and is associated with increased morbidity and mortality. It occurs rarely in children and is seen frequently among the adults. Malaria associated renal failure may occur as a sole complication or as a component of multiple complications. Some of the patients may have normal urination (non-oliguric) and usually have better prognosis even without renal replacement therapy. Only a few research studies are available from Indian subcontinent on malarial acute renal failure. The present study is a hospital based study from eastern India. Rourkela is situated in the western part of Orissa which contributes a large number of falciparum malaria cases. The study was conducted at the internal medicine department of Ispat General Hospital. The clinical presentation of malaria patients in 2001 were analysed with special emphasis on malarial acute renal failure. The difference between patients with or without renal failure was compared. Seven hundred eighteen patients admitted to Ispat General Hospital in 2001 above the age of 14 years were analysed. Of these, 84 (11.8%) had serum creatinine >3 mg/dl. Seventy-five patients were referred from different hospitals outside the township. The presenting complaints were fever (95%), oliguria (55%); loose motions (25%), and vomiting (51%). Headache was present in only 20% patients. Similarly, hypotension was encountered in about a third. Associated complications were significantly more common among patients having renal failure viz, Jaundice (77 versus 19%; p < 0.001), Cerebral malaria (59 versus 11%; p < 0.001), and hypoglycaemia (p < 0.05). The mortality in presence of acute renal failure was high (p < 0.001). Though malaria renal failure is a burning issue, still scant data is available in the literature, including India. The present study is an attempt to study the patients admitted to a referral hospital. The reason for high mortality is due to presence of multiple complications. The present study indicates that the presence of acute renal failure and jaundice together adversely influences the mortality. Hence, studies may be carried out to find out the reason of this changing trend as well as the methods to ameliorate/manage the situation.

US$29.90

PMID: 19552096


Other references

Honma, H., 1977: Respiratory bronchiolitis--with special reference to the chronic type--clinical studies of diffuse panbronchiolitis. Kokyu to Junkan. Respiration & Circulation 25(1): 37-46

Ascer, E.; Pimentel Filho, W.A.; Büchler, J.R.; Hirschfeld, R.; de Assis, S.F.; Neves, M.; Araújo, E.C.; Pinheiro, L.F.; Saad, J.; Armelin, E., 1992: Coronary angioplasty in octogenarians. To evaluate the indications, results and follow-up of patients with 80 years old and over, who had undergone percutaneous transluminal coronary angioplasty (PTCA). From July 1987 through July 1990, 36 patients, 80 years of age and over, had PTCA a...

Davtyan N.K.; Lipunova Z.I., 1972: Effect of lyophilized serum dialysate of patients with diabetes mellitus on lipolytic activity of adipose tissue and its glucose utilization. Problemy Endokria 18(3): 30-32

Steen V.; Ziegler G.L.; Rodnan G.P.; Medsger T.A.Jr, 1982: Clinical associations of anti centromere antibody in patients with progressive systemic sclerosis. Arthritis & Rheumatism 25(4 SUPPL): S4

Watson, H.K.; Beebe, R.D.; Cruz, N.I., 1984: A centralization procedure for radial clubhand. A modified centralization procedure for radial club hand caused by partial or total absence of the radius is presented. This technique differs from the methods presently used in that no carpal bones are resected. Adequate release of the wrist from...

Nakamura, M.; Kido, Y.; Egawa, T., 2008: Development of a 32-item scale to assess postoperative dysfunction after upper gastrointestinal cancer resection. The purpose of this study was to develop a 32-item scale to assess postoperative dysfunction in patients who underwent surgery for gastric and oesophageal cancer and to evaluate its reliability and validity. For the objective assessment of postope...

Usuku G., 1973: Studies on the collagen formation and resorption part 2. Bulletin of the Institute of Constitutional Medicine Kumamoto University 23((SUPPL)): 1-62

Binkley F., 1982: Localized elaboration of immuno globulin a in primary murine mammary cell culture relationship to fibronectin matrix and time in culture. Federation Proceedings: Abstract 4034

Hütt, P.; Songisepp, E.; Rätsep, M.; Mahlapuu, R.; Kilk, K.; Mikelsaar, M., 2016: Impact of probiotic Lactobacillus plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults. The blood pressure-lowering effect of dairy products holds the potential to decrease the risk of cardiovascular disease (CVD). An open question is if the successful expression of functional properties of the probiotic strain depends on host biomar...

Sivanesan A., 1984: Teleomorphs of clasterosporium anomalum and clasterosporium cyperi new genus new species. Transactions of the British Mycological Society 83(4): 710-718