+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Management of oncology patients admitted to the paediatric intensive care unit of a general children's hospital - a single center analysis

, : Management of oncology patients admitted to the paediatric intensive care unit of a general children's hospital - a single center analysis. Klinische Padiatrie 223(3): 142-146

The improving prognosis of children with cancer has partially been attributed to the increasing importance of pediatric intensive care units (PICU). We analyze whether outcome of these patients on a PICU improved during the last decade and which factors may influence the outcome in our hospital. The charts of all oncology patients admitted to the PICU between 1998 and 2009 have been reviewed retrospectively. The survival of patients admitted for life threatening complications has been correlated with basic data, organ failure and the PRISM score. The results of 2 consecutive treatment periods (1998-2003 and 2004-2009) were compared. 644 admissions of 226 patients were recorded. 79 admissions were performed because of potentially life threatening complications (Group A), 236 for monitoring (B) and 329 admissions for interventions (C). 62% of Group A patients and all Group B and C patients were discharged alive. Poor outcome was associated with admission >28 days after initial diagnosis, PRISM >10, organ failure >2 organs, sepsis, allogeneic stem cell transplantation, need for mechanical ventilation or for catecholamines. The PICU survival rate of Group A patients admitted between 2004 and 2009 (78%) was higher than in the period between 1998 and 2003 (48%). PICU provides essential services to support the pediatric oncology ward. Although children with cancer may have had benefit from advances in pediatric intensive care over the past decade, specific scoring systems for early identification of children with cancer needing PICU treatment are required. These systems might further improve PICU outcome in critical ill pediatric cancer patients.


PMID: 21567369

DOI: 10.1055/s-0031-1275291

Other references

Almeida, J.I.; Wakefield, T.; Kabnick, L.S.; Onyeachom, U.N.; Lal, B.K., 2016: Use of the Clinical, Etiologic, Anatomic, and Pathophysiologic classification and Venous Clinical Severity Score to establish a treatment plan for chronic venous disorders. To be useful in clinical practice and in the evaluation of clinical therapies for chronic venous disorders, a measurement instrument should be objective, inclusive of all severities of venous disease, and rapidly performed by clinicians. The Clini...

Denoix, J.M., 2000: The equine distal limb: an atlas of clinical anatomy and comparative imaging. Jean-Marie Denoix is the world's leading equine musculoskeletal system anatomist and has become one of the foremost equine diagnostic ultrasonographers. There is therefore nobody better to compile a reference atlas of the clinical anatomy of...

Bathon, H., 1985: Kaferfunde der Jahre 1982 bis 1984 aus Hessen 2. Bericht der Arbeitsgemeinschaft hessischer Koleopterologen. Naturwissenschaftlicher Verein Darmstadt Bericht N F: 9: 20-29

Burchfield, P.M.; Beimler, T.F.; Doucette, C.S., 1982: An unusual precoital head-biting behavior in the Texas patchnosed snake, Salvadora grahamae lineata Reptilia Serpentes Colubridae. Copeia

Kilbride, H.W.; Thorstad, K.; Turnbull, W.; Claflin, K., 2002: Higher cognitive scores for 801 g birth weight survivors at 6 years born in 1990s compared to those from 1980s. Pediatric Research 51(4 Part 2): 409A, April

Westwood, I.M.; Kawamura, A.; Russell, A.J.; Sandy, J.; Davies, S.G.; Sim, E., 2011: Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening. Arylamine N-acetyltransferases (NATs) are a family of enzymes found in eukaryotes and prokaryotes. While the precise endogenous function of NAT remains unknown for most organisms, recent evidence has shown that the expression of human NAT1 is up-r...

Wagner, D., 1997: The little red book - golf in China. That golf course development is forging ahead with little respect for existing natural and human landscapes is described. The ways in which developers have taken advantage of cheap land, labour and a top down totalitarian political system in the p...

Eisenberg, J.M.; Kabcenell, A., 1988: Organized practice and the quality of medical care. Larger, more complex medical care organizations have the inherent capability to improve the quality of the care they deliver because of the improved competency that follows higher volumes of service, the interdependence of staff, and the emergence...

Oppenheimer, H., 1963: A program for management of diabetes. Missouri Medicine 60: 261-261

Vanselow, K.; Heuck, F., 1975: New principles and theories for improving angio-cinedensitometry. I. The physical principles of quotient densitometry(author's transl). The physical basis of quotient densitometry is described. All stages are discussed, beginning with the production of the x-rays, their attenuation by the patient, their effect on the radiographic film, and the evaluation of the film by projection...