+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Managing femoral head osteonecrosis in patients with sickle cell disease

, : Managing femoral head osteonecrosis in patients with sickle cell disease. Surgeon 5(5): 282-289

With an increasing number of people immigrating between different countries, sickle cell disease (SCD) is spreading all over the world. Due to improved health care, the life span of SCD patients has increased and many of them live to adulthood and middle-age. Osteonecrosis of the femoral head is one of the most common musculo-skeletal problems in SCD patients. Once osteonecrosis starts in the femoral head, it can progress from early to late stages in just a few years. Managing osteonecrosis of the femoral head in young-adults is a challenging problem and, in many situations, it requires major surgical procedures. In the early stages of the disease it is advisable to treat it by femoral head preserving procedures. In advanced stages, hip replacement arthroplasty (HPA) is indicated. In SCD patients, the incidence of operative complications and failure rates are higher than that for osteonecrosis due to other causes. Understanding the problems of SCD patients; appropriate diagnosis, prognosis, implications of the procedure performed and taking the necessary precautions, can reduce the complications and delay the failure of surgical procedures.


PMID: 17958228

Other references

Hamade, R.; Yamamori, N., 2000: Method for controlled release of compounds having antimicrobial activity and coating composition. A novel method for controlled release of compounds having antimicrobial activity and a novel coating composition capable of controlled release of compounds having antimicrobial activity is provided. This invention relates to a method for releasing...

Etheredge, E.E.; Sicard, G.A.; Anderson, C.B., 1979: Immunologic correlates of human renal allograft survival. Transplantation Proceedings 11(1): 354-359

Fasasi, O.S.; Adeyemi, I.A.; Fagbenro, O.A., 2005: Proximate composition and multi-enzyme in vitro protein digestibility of maize-tilapia flour blends. The study aims at reducing the post harvest loss of Nile Tilapia (Oreochromis niloticus) in the riverine areas of Africa, by introducing the underutilized species of fish into human food chain to produce a high-quality protein cereal gruel. O. nil...

Gillissen, A., 2007: Are athletes really at risk of asthma (Interview by Maria Weiss). Mmw Fortschritte der Medizin 149(42): 21-21

Collignon, A.; Edelman, L.; Scherrmann, J.M., 1984: A comparative study between animals and monoclonal anti-digitoxin antibodies. Anti-digitoxin antibodies have been produced by immunizing rabbits and by monoclonal techniques using the same digitoxin-protein conjugate. Titres, inhibition curves, affinities, dissociation and association rate-constants have been investigated f...

Chang, C-Chao.; Lin, Y-Ting.; Lu, Y-Ting.; Liu, Y-Shian.; Liu, J-Fang., 2011: Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation. Irritable bowel syndrome (IBS) is a common functional disorder of the gastrointestinal system, and is characterized by abdominal pain, diarrhea (IBS/D), constipation (IBS/C), and alternating diarrhea and constipation (IBSC/A). The purpose of this...

Messinger, P.; Meyer, H., 1976: The reaction of iodohydroxyquinolinesulfonic acid with nitrite. Archiv der Pharmazie 309(12): 1009-1010

Stasi, K.; Chuck, R.S., 2009: Update on phototherapeutic keratectomy. To review all recent publications on the use of phototherapeutic keratectomy (PTK). Recent studies confirm the beneficial outcomes of PTK in a variety of anterior corneal disorder: anterior stromal scars, dystrophies of the corneal epithelium and...

Ezmirly, S.T.; Cheng, J.C.; Wilson, S.R., 1979: Saudi Arabian medicinal plants: Salvadora persica. The Saudi Arabian toothbrush tree Salvadora persica has been used as a brushing stick for over 1000 years. Extracts of the plant have yielded sulfur as a major constituent. In addition, pharmacological data indicate antibiotic, anti-inflammatory,...

Sciortino; Tartaglia, 2001: Extension of the Fluctuation-Dissipation Theorem to the Physical Aging of a Model Glass-Forming Liquid. We present evidence in favor of the possibility of treating an out-of-equilibrium supercooled simple liquid as a system in quasiequilibrium. Two different temperatures, one controlled by the external bath and one internally selected by the system,...