+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Maternal age-associated congenital anomalies among newborns: a retrospective study in Latvia

, : Maternal age-associated congenital anomalies among newborns: a retrospective study in Latvia. Medicina 49(1): 29-35

In Latvia, the mean age of women giving birth increased from 27.3 in 2000 to 29.0 years in 2010 during the last 11 years. The aim of this study was to report on major congenital anomalies of newborns at birth by the maternal age and to compare the mean maternal age by different diagnosis subgroups and maternal and neonatal characteristics. A cross-sectional retrospective study with the data from the Medical Birth Register (2000-2010) was carried out. The live birth prevalence rate was calculated for the subgroups of major congenital anomalies per 10 000 live births by the maternal age. The live birth prevalence rate of major congenital anomalies during the period 2000-2010 was 211.4 per 10 000 live births. The prevalence rate increased depending on the maternal age. Congenital heart defects, limb defects, and urinary system anomalies were the most common anomalies. The study results showed an age-related risk of abdominal wall defects, orofacial clefts, and chromosomal anomalies. There were significantly higher proportions of preterm births, newborns with low birth weight, and complications during pregnancy among mothers aged 35 years and more. The data on congenital anomalies from the Latvian Medical Birth Register can be used for the assessment of epidemiology of congenital anomalies. The results of this retrospective study showed a decrease in the live birth prevalence rate of major congenital anomalies despite an increase in the mean age of mothers in Latvia.


PMID: 23652715

Other references

Liu, S.; Xing, J.; Zheng, Z.; Song, F.; Liu, Z.; Liu, S., 2012: Ultrahigh performance liquid chromatography-triple quadrupole mass spectrometry inhibitors fishing assay: a novel method for simultaneously screening of xanthine oxidase inhibitor and superoxide anion scavenger in a single analysis. Xanthine oxidase (XOD) inhibitors and superoxide anion scavengers play an important role in the treatment of gout and the inhibition of many diseases related to superoxide anion. The respective quantitation of uric acid and superoxide anion by tra...

Vincenz C.; Fronk J.; Tank G.A.; Langmore J.P., 1988: Nucleoprotein hybridization a method for the enrichment of early sea urchin histone genes. Journal of Cell Biology 107(6 PART 3): 311A

Kaker, M.L.; Singal, S.P.; Razdan, M.N., 1977: Lactate & succinate dehydrogenase activities of semen from young crossbred bulls during winter. Indian Journal of Experimental Biology 15(2): 145-146

Birdsall, M.A.; Rees, M.C.P., 1997: Women referred to a specialist menopause clinic with premature ovarian failure. Maturitas 27(SUPPL ): 149

Tarnawsky, S.P.; Palazzo, A.F., 2013: Positional requirements for the stimulation of mRNA nuclear export by ALREX-promoting elements. The majority of vertebrate mRNAs that encode secreted, membrane-bound or mitochondrial proteins contain elements at the 5' end of the ORF that activate an alternative mRNA nuclear export (ALREX) pathway. Here we demonstrate that these element...

Waisser, K.; Perina, M.; Kunes, J.; Klimesova, V.; Kaustova, J., 2003: 3-Benzyl-2H-1,3-benzoxazine-2,4(3H)-diones, a new group of antimycobacterial compounds against potentially pathogenic strains. A series of derivatives of 3-benzyl-2H-benzoxazine-2,4(3H)-dione substituted in positions 6, 7 or 8 on the benzoxazine, and in positions 3 or 4 on the benzyl moiety was synthesized. The compounds were evaluated for in vitro antimycobacterial activ...

Parz-Gollner, R.; Brader, M., 2002: Distribution of migrating cormorants Phalacrocorax carbo sinensis in Upper Austria during the winter seasons 1999/2000 and 2000/2001 Durchzug und Verbreitung des Kormorans Phalacrocorax carbo sinensis in Oberoesterreich in den Wintersaisonen 1999/2000 und 2000/2001. Vogelkundliche Nachrichten aus Oberoesterreich Naturschutz Aktuell, 101: 1-18

Shen,; Constable, I.J.; Chelva, E.; Rakoczy, P.E., 2000: Inhibition of diclofenac formulated in hyaluronan on angiogenesis in vitro and its intraocular tolerance in the rabbit eye. Purpose: To investigate the effect of diclofenac, a potent nonsteroidal anti-inflammatory drug, formulated in hyaluronan (diclofenac/HA) on angiogenesis in vitro and its intraocular toxicity in vivo. Methods: The effect of diclofenac/HA on angioge...

Malmheden Yman, I.; Edberg, U., 1990: Estimation of gluten in different foods. Gluten was estimated in selected products by quantitative enzyme immunoassay (Qlone test) and by semiquantitative dot blotting method. All 28 foods marketed in Sweden as gluten-free products contained acceptably minimal amounts of gluten or none a...

Vjark, E Vark, E., E.Al., 1968: On the extraction of photosynthetic products by ethanol solutions. From bean leaf discs exposed to 14CO2, sugars, amino acids, organic acids and some unidentified compounds were completely extracted by 80% and 40% ethanol. Sugar phosphates were partially extracted by these solvents and completely by distilled wat...