geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Mechanisms of hypoxemia episodes in spontaneously breathing preterm infants after mechanical ventilation


, : Mechanisms of hypoxemia episodes in spontaneously breathing preterm infants after mechanical ventilation. Neonatology 94(2): 100-104

Preterm infants often present with recurrent episodes of hypoxemia after mechanical ventilation. To evaluate the role of abdominal muscle activity and central apnea on the frequency and severity of hypoxemia episodes (HEs) in preterm infants with a history of mechanical ventilation. Continuous recordings of arterial oxygen saturation (SpO(2)), gastric pressure, respiratory inductance plethysmography and abdominal surface electromyography were obtained during 4 h from spontaneously breathing preterm infants who had recently been extubated and presented with frequent HEs. Ten infants (gestational age 26.4 +/- 1.1 weeks, body weight 816 +/- 128 g, age 44 +/- 21 days, FiO2 0.31 +/- 0.09, mechanically ventilated for 33 +/- 37 days) were studied 12 +/- 7 (mean +/- SD) days after extubation. These infants presented with 10.2 +/- 9.3 HEs/h (SpO2 <88%, > or =10 s). Of these, 8.2 +/- 6.2 HEs/h were associated with abdominal muscle contraction while only 2.0 +/- 4.5 HEs/h were associated with > or =10 s apnea (p < 0.05). Of the more severe HEs (SpO(2) <75%, > or =10 s), 2.7 +/- 3.1 HEs/h were associated with abdominal contraction and only 0.7 +/- 2.1 HEs/h with apnea (p < 0.05). Resting lung volume decreased by 69 +/- 16% of tidal volume in HEs associated with abdominal contraction. In this group of premature infants who presented with frequent HEs after mechanical ventilation, most HEs were associated with abdominal muscles contraction and a loss in lung volume. These findings provide an alternate mechanism to explain these episodes in spontaneously breathing preterm infants with a history of mechanical ventilation.

US$19.90

PMID: 18277057

DOI: 10.1159/000116634


Other references

Balasta, M.L.; Friedland, D.E.; Sha, M.; Goss, D.J., 1993: Fluorescence spectroscopic studies of the interactions of wheat germ eukaryotic initiation factors eIF-4F, eIF-4B, and eIF-4A with RNA. Biophysical Journal 64(2 PART 2): A278

Chen Hai hong; Sun Shu; L.J.liang; Hsu Kenneth J.; Heller Friedrich; Dobson Jon, 1992: Rotation of the Hunan Block, South China. Chinese Science Bulletin 37(22): 1899-1902

Thiesemann, R.; Kruse, W.H.H.; Meier-Baumgartner, H.P., 1997: Application of clinical databases for gerontological and geriatric quality assurance: Principles and constructional demands. Geriatric institutions enforce clinical documentation in order to assure quality of care. Different means include basic information of the clinical course, data gathering by administration and extractions from research projects. The use of electro...

Grosse-Brauckmann, G., 1978: Absolute annual pollen deposition rates at various sampling sites in the Federal Republic of Germany. Flora: 67 (3 4) 209-247

Benedetto, U.; Jin, X.Yu.; Hill, E.; Treasure, T.; Petrou, M., 2016: An Option for Concomitant Management of Moderate Marfan Root Aneurysm at the Time of Mitral Valve Repair: A Role for Personalized External Aortic Root Support. NlmCategory="UNASSIGNED">Two patients had mitral valve repair for severe regurgitation in the presence of a Marfan aortic root aneurysm. Concomitant personalized external aortic root support was used at the same operation to halt aneu...

Korotchkin, L.I., 1966: Morphological and cytochemical divergency in neurocytogenesis of vegetative neurons. Morphology and cytochemistry of the development of vegetative neurons of digestive tube and sympathetic chain in a man was investigated. Some general principles of differentiation of these groups of neurons are discovered. Numerous structural chem...

Shen BaiZhen; Horibe, K.; Oshita, S., 1996: Studies on thermal properties of food (part 2). Intrinsic thermal conductivity of sugar and heat transfer mechanism of food model. In this study, 6 types of food were represented by mixed gels containing 2.4% agar, 10.4-59.0% sugar and 87.2-38.6% water. For each gel, the thermal diffusivity was measured using a flash method; the density and specific heat were determined by ot...

Meunier, M., 1950: Preliminary reports on prefrontal lobotomy; the psychological aspects. Treatment Services Bulletin. Canada. Department of Veterans' Affairs 5(7): 363-366

Izadpanahi, M.Hossein.; Honarmand, R.; Khorrami, M.Hataf.; Najarzadegan, M.Reza.; Sichani, M.Mohammadi.; Alizadeh, F., 2015: A comparison of bladder neck preservation and bladder neck reconstruction for urinary incontinence after radical retro pubic prostatectomy. Prostate cancer is the sixth most common cancer worldwide and will include about 30% of all malignancies in men. Since the initial report of the anatomic radical prostatectomy, refinements in the surgical technique have been made. Several studies...

Germaniuk, I.L.; Sidorenko, D.S., 1974: Amino acid incorporation into subcellular fraction protein in the rat liver under the influence of multiple injections of ACTH and ACTH in combination with RNA. Ukrains'kyi Biokhimichnyi Zhurnal 46(4): 438-440