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Microscopic diffusion tensor imaging of the mouse brain


, : Microscopic diffusion tensor imaging of the mouse brain. Neuroimage 50(2): 465-471

Diffusion tensor imaging (DTI) data at 43 mum isotropic resolution has been acquired on the intact adult mouse brain in 28-h scan time by using a streamlined protocol, including specimen fixation and staining, image acquisition, reconstruction, post-processing, and distribution. An intermediate registration of each component image is required to achieve the desired microscopic resolution. Multiple parameters have been derived, including fractional anisotropy, axial and radial diffusivity, and a color-coded orientation map of the primary eigenvector. Each DTI dataset was mapped to a common reference space to facilitate future standardized analysis. Fiber tracking has also been demonstrated, providing 3D connection information. This protocol to acquire high-resolution DTI data in a robust and repeatable fashion will serve as a foundation to quantitatively study mouse brain integrity and white matter architecture, at what we believe to be the highest spatial resolution yet attained.

US$19.90

PMID: 20034583

DOI: 10.1016/j.neuroimage.2009.12.057


Other references

Anderson, J.U.; Fadul, K.E.; O.C.nnor, G.A., 1973: Factors affecting the coefficient of linear extensibility in vertisols. In horizon samples from ustert and torrert profiles from the Sudan, Arizona and New Mexico, the coefficient of linear extensibility was highly correlated with percent fine clay plus ESP. A predictive model which assumes that these vertisols expand...

Saccani Emilio; Beccaluva Luigi; Coltorti Massimo; Siena Franca, 2004: Petrogenesis and tectono-magmatic significance of the Albanide-Hellenide ophiolites. International Geological Congress, Abstracts = Congres Geologique International, Resumes 32, Part 1: 373

Warabieda, W.; Miszczak, A.; Olszak, R.W., 2004: The influence of methyl jasmonate and beta-glucosidase on induction of apple tree resistance mechanisms to two-spotted spider mite (Tetranychus urncae Koch.). The objective of the research was to determine the influence of methyl jasmonate (JA-Me) and beta-glucosidase on the mechanisms of apple tree resistance to T. urticae like antibiosis and non-preference. The experiments were conducted on leaves of...

Pantaleo, P.; Lagi, A.; Laffi, G.; Cencetti, S.; Barletta, G.; L.V.lla, G., 2001: Altered autonomic modulation of cerebral blood flow in cirrhosis. Journal of Hepatology 34(Supplement 1): 63, April

Reese, A.J.; Nunn, J.F., 1961: An apparatus for administering known concentrations of volatile anaesthetics to small laboratory animals. British Journal of Anaesthesia 33: 54-57

Koopman, M.M., 1999: Outpatient treatment of deep vein thrombosis with LMWH. Low-molecular-weight heparin therapy is safe and effective in the treatment of patients with acute deep vein thrombosis. These compounds are administered subcutaneously, without a need for laboratory control. This has made possible to treat patien...

Ahmed, A.M.; Shinoda, S.; Shimamoto, T., 2004: A variant type of Vibrio cholerae SXT element in a multidrug-resistant strain of Vibrio fluvialis. Vibrio fluvialis strain H-08942 was isolated from an infant aged 6 months who was suffering from cholera-like diarrhea in India. This strain showed the typical multidrug-resistance phenotype of an SXT element. It was resistant to sulfamethoxazole...

Einsele, H.; Meisner, C.; Straka, C.; Schmidt, H.; Schmidberger, H.; Hebart, H.; Truemper, L.; Mueller, R.; Schlimok, G.; Hertenstein, B.; Kroeger, N.; Zander, A.R.; Hossfeld, D.; Peest, D.; Metzner, B.; Budach, W.; Frickhofen, N.; Bamberg, M., 2001: Total marrow irradiation, busulfan and cyclophosphamide followed by PBSCT in patients with advanced multiple myeloma. The overall survival of patients with advanced multiple myeloma (MM) undergoing high-dose chemotherapy and autologous stem cell transplantation (SCT) was found to depend mainly on the quality of response. Thus, to improve the response rate, a new...

Blais, M-Claude.; Maunsell, E.; Grenier, S.; Lauzier, S.; Dorval, M.; Pelletier, S.; Guay, Séphane.; Robidoux, Aé.; Provencher, L., 2015: Validating the content of a brief informational intervention to empower patients and spouses facing breast cancer: perspectives of both couple members. The study objectives were to identify key information components that would be the basic content of a brief informational intervention, developed from a population perspective, to empower individual couple members facing breast cancer and to valid...

Soltan, S.A.; Abdel Salam, A.A.; Nasef, M.K., 2002: Impact of interaction between zinc and iron or cadmium on wheat yield and elemental composition. Four incubation and greenhouse pot experiments were conducted to evaluate the effect of interaction between Zn (sulfate form at 0, 5, 10 and 20 micro g/g soil), and Fe and Cd (sulfate and chloride forms, respectively, at 0, 1, 2 and 4 micro g/g so...