geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Multiple risk factor clustering and risk of hypertension in the Mongolian ethnic population of China


, : Multiple risk factor clustering and risk of hypertension in the Mongolian ethnic population of China. Biomedical and Environmental Sciences 20(5): 381-385

To evaluate whether the clustering of risk factors, both environmental and genetic, increases the risk of essential hypertension (EH) and the accumulation of risk factors influences the blood pressure level in normotensives. On the basis of a prevalence survey, 501 subjects of Mongolian ethnicity (243 hypertensives and 258 normotensives) who were not related to each other were selected to conduct a case-control study. All subjects were interviewed with questionnaires and their blood specimens were collected. Renin gene insertion/deletion (I/D) polymorphism, a new genetic marker, was genotyped with PCR and polyacrylamide gel electrophoresis. Overweight, alcohol consumption, and renin gene I/D polymorphism were significant risk factors of EH (P<0.05). The odds ratios (OR) for the number of risk factors were 2.39 (95%CI: 0.98-6.74) for one risk factor, 5.03 (95%CI: 2.06-14.18) for two, and 6.09 (95%CI: 1.85-22.38) for three respectively after adjusting for age and sex. In normotensives, age- and sex-adjusted mean blood pressures increased with more accumulation of risk factors. However, there were no significant differences among the different blood pressure levels according to the number of risk factors (P>0.05). Overweight, alcohol consumption, and renin gene I/D polymorphism are risk factors of EH in the Mongolian ethnic population of China. The accumulation of the risk factors causes a sharp increase of the risk of EH.

US$29.90

PMID: 18188989


Other references

Cook, A.M.; Daughton, C.G.; Alexander, M., 1978: Phosphonate utilization by bacteria. Bacteria able to use at least one of 13 ionic alkylphosphonates or O-alkyl or O,O-dialkyl alkylphosphonates as phosphorus sources were isolated from sewage and soil. Four of these isolates used 2-aminoethylphosphonic acid (AEP) as a sole carbon, n...

Hogan, M.; MacDonald, J.; Olness, K., 1984: Voluntary control of auditory evoked responses by children with and without hypnosis. This is the 1st reported study of the ability of children to voluntarily change brainstem auditory evoked responses (BAER). Fifteen children were studied. Both control and hypnosis groups showed changes in interwave latencies after verbal suggesti...

Daccordi, M. .; Giachino, P.M. ., 2005: Results of the zoological missions to Australia of the Regional Museum of Natural Sciences of Turin, Italy. II. Museo Regionale di Scienze Naturali Monografie (Turin): 42: 1-643

Sawahara, K.; Ishikawa, K.; Endo, N.; Mawatari, M., 1993: Some technological developments in a packaging line. Journal of the Institute of Brewing 99(3): 205

Twomey, S.L.; Sweat, R., 1975: Radioimmunoassay for triiodothyronine: use of polyethylene glycol to precipitate immune complexes. 1. A rapid radioimmunoassay (RIA) for determining serum triiodothyronine (T3) concentration has been developed. The reaction of T3 with its antibody was performed at 37 degrees C for 3 hours; precipitation of antibody bound T3 by 15% polyethylene...

Sekhar, R.V.; Goodman, J.Clay.; Balasubramanyam, A.; Tatro, J.B.; Mihaly, E., 2005: Regulation of body weight by proopiomelanocortin peptides in humans: lessons from the Nelson syndrome. Annals of Internal Medicine 143(3): 238-239

Hao, X.; Godlinski, F.; Chang, C., 2008: Distribution of phosphorus forms in soil following long-term continuous and discontinuous cattle manure applications. Better information on soil P and its distribution in various forms is needed to assess their bioavailability and environmental impact. This study investigates the distribution of P forms following long-term manure application to a calcareous clay...

Demicheli, R.; Jirillo, A.; Bonciarelli, G.; Bellini, A.; Petrosino, L.; Bigi, L.; Garusi, G.F., 1982: Pharmacological data and technical feasibility of intraperitoneal 5-fluorouracil administration. Via a surgically implanted Tenckhoff catheter, 5-fluorouracil was intraperitoneally administered to patients with malignant disease confined to abdominal space. Treatment was well tolerated without local complications. Peritoneal and plasmatic dru...

Neirinckx, E.; Vervaet, C.; D.B.ever, S.; Remon, J.P.; Gommeren, K.; Daminet, S.; D.B.cker, P.; Croubels, S., 2010: Species comparison of oral bioavailability, first-pass metabolism and pharmacokinetics of acetaminophen. Species differences in oral bioavailability, first-pass metabolism and pharmacokinetics of biopharmaceutics classification system (BCS) class I compound acetaminophen were studied. The absolute bioavailability was 42.2%, 39.0%, 44.5%, 75.5% and 91...

Cayley, W., 2010: Patients as allies in student education and rural recruitment. Family Medicine 42(4): 288-288