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Mycobacterium chelonae keratitis in a patient with Sjögren's syndrome

, : Mycobacterium chelonae keratitis in a patient with Sjögren's syndrome. European Journal of Ophthalmology 18(2): 294-296

In this report a case of Mycobacterium chelonae keratitis in a patient without any previously described risk factors is described. The only risk factor found was a rheumatoid arthritis related Sjogren''s syndrome. Case report. A 60-year-old woman was referred to the hospital with an infectious keratitis of the left eye of 3 months duration, unresponsive to empirical therapy with ofloxacin and tobramycin drops. Her medical history included a longstanding rheumatoid arthritis and a secondary ocular surface syndrome. Upon arrival the left eye showed diffuse corneal edema and centrally several large infiltrates with fluffy edges, surrounded by several smaller satellite infiltrates. The cornea was scraped for culture and grew M chelonae and sensitivity testing showed sensitivity to ciprofloxacin, clofazimine, and clarithromycin. Systemically, ciprofloxacin 750 mg and clarithromycin 500 mg twice daily were prescribed orally. Topical therapy consisted of topical erythromycin 10 mg/mL and ofloxacin 3 mg/mL every 2 hours. Treatment was continued for a total of 10 months during which the infiltrates cleared completely, but the central cornea remained scarred. M chelonae can be a cause of infectious keratitis in patients without known risk factors for rapidly growing mycobacterium keratitis. Especially in the case of ocular infections that show no response to regular antibacterial treatment, mycobacterial infection should be considered. Good communication between the ophthalmologist and the microbiologist is crucial for a rapid diagnosis.


PMID: 18320526

Other references

Richards, LP.; Bock, WJ., 1973: Functional anatomy and adaptive evolution of the feeding apparatus in the Hawaiian honeycreeper genus Loxops (Drepanididae). Ornithological Monographs, No1: 1-173

Lu, J.; Prabakaran, S.; Edmunds, J.W.; Aukema, H.M., 2000: Dietary fish oil delays progression of kidney disease in HanSPRD-cy rats. FASEB Journal 14(4): A738, March 15

Coyle, J.T., 1999: Ice-nine and human prion disease. Harvard Review of Psychiatry 6(6): 331-333

Anonymous, 1967: Protriptyline (Concordin) - another tricyclic antidepressant. Drug and Therapeutics Bulletin 5(17): 67-67

Sameoto D.D., 1984: Environmental factors influencing diurnal distribution of zooplankton and ichthyoplankton. The diurnal vertical distribution of a large number of species of zooplankton, ichthyoplankton and micronekton were determined in the top 150 m in 3 locations in the Shelf Water, on the Nova Scotia [Canada] Shelf and Slope and on Georges Bank duri...

Pust, R.E.; Binns, C.W.; Weinhold, D.W.; Martin, J.R., 1985: Palm oil and pyrantel as child nutrition mass interventions in Papua New Guinea. Two mass interventions in the local low energy-density diet were evaluated for safety, acceptability and nutritional efficacy in a four-group matched study of 896 Papua New Guinea children aged 12-54 months. A single dose of 125 mg of pyrantel pam...

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Spikes, J.M.; Schutzenhofer, K.K., 1987: The coordinated course: efficient and effective. Nurse Educator 12(4): 4-4

Talmadge, Robert J., 2000: Myosin heavy chain isoform expression following reduced neuromuscular activity: Potential regulatory mechanisms. In this review, the adaptations in myosin heavy chain (MHC) isoform expression induced by chronic reductions in neuromuscular activity (including electrical activation and load bearing) of the intact neuromuscular unit are summarized and evaluated...

Watkins, S.F.; Kim, S.J.; Fronczek, F.R.; Voll, R.J.; Younathan, E.S., 1990: The X-ray crystal structure of 2,3:4,5-di-O-isopropylidene-1-O-methyl-beta-D-fructopyranose. 2,3:4,5-Di-O-isopropylidene-1-O-methyl-beta-D-fructopyranose, C13H22O6, Mr = 274.3, orthorhombic, P212121, a = 12.388 (2), b = 13.307 (5), c = 8.660 (1) A, V = 1427.4 (9) A3, Z = 4, Dm = 1.24, Dx = 1.276, CuKalpha, lambda = 1.54184 A...