+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Non-Hodgkin lymphoma of the mandible--a case report with differential diagnostic considerations

, : Non-Hodgkin lymphoma of the mandible--a case report with differential diagnostic considerations. Schweizer Monatsschrift für Zahnmedizin 121(5): 449-460

Approximately 5% of all malignant lesions are diagnosed as malignant lymphomas, of which 2-3% are localized in the head and neck region. After the squamous cell carcinoma and neoplasms of the salivary glands, malignant lymphomas represent the third most frequent malignant lesion in that region. Malignant lymphomas can be grouped into Hodgkin- and non- Hodgkin lymphomas (NHL) and subdivided into nodal (lymph nodes) and extranodal lymphomas. We present the case of an extranodal non-Hodgkin lymphoma in the left mandible of a 47-year-old woman, who was referred to our department with an unclear swelling, which was supposed to be infectious. After clinical and radiological examination, a biopsy was taken and a CD20 and BCL-6 protein positive non-Hodgkin lymphoma of the large B-cell type (DLBCL) was diagnosed. The patient was treated primarily with immunochemotherapy (R-CHOP protocol) and refused to undergo a subsequent radiotherapy. The 18 months follow-up showed a complete remission of the lymphoma. In this paper, the NHL in the oral and maxillofacial region is presented as a cause of unclear swelling. Important differential diagnostic conditions are discussed.


PMID: 21656387

Other references

Smith, W.G., 1962: The slow reacting substance of anaphylaxis: its identification as a mixture of glycosides of neuraminic acid. Life Sciences 1: 133-140

Eichmeier Max, 1936: Die kandische Praerie als Wirtschaftsraum. Pages 129-299 1936

Borschmann, R.; Patton, G.C., 2017: The outcomes of adolescent mental disorders. Acta Psychiatrica Scandinavica

Liu, S.; Dixon, K., 1996: Induction of mutagenic DNA damage by chromium(VI) and glutathione. Certain chromium (Cr) compounds are known to be carcinogenic in humans and mutagenic in cell culture. However, the mechanism of Cr mutagenesis is not well understood. It appears that intracellular reduction of Cr by agents such as glutathione play...

Sybert A.; Knoblauch A.; Sylvester J.T.; Gurtner G.H., 1979: Oxygen dependence of o demethylation of p nitro anisole in the isolated perfused rabbit lung. Federation Proceedings 38(3 PART 1): 1329

Francl L.J.; Wyllie T.D.; Rosenbrock S.M., 1988: Influence of crop rotation on population density of macrophomina phaseolina in soil infested with heterodera glycines. Soil populations of Macrophomina phaseolina, cause of charcoal rot of soybean [Glycine max] and various rots and blights of a large number of cultivated plants, might be managed by crop rotation if the density of infective microsclerotia in soil c...

Rothschild, M., 1955: Diurnal movements of the Mountain Chough (Pyrrhocorax graculus) in the Wengen and Kleine Scheidegg (Bernese Oberland) areas during the months of January, February and March. Int Orn Congr, 111954: 611-617

Gopalan, A.I.; Lee, K-P.; Komathi, S., 2011: Bioelectrocatalytic determination of nitrite ions based on polyaniline grafted nanodiamond. Polyaniline chains were grafted onto nanodiamond (PANI-g-ND) through electrochemical polymerization of aniline in the presence of amine functionalized ND. A robust and effective composite film comprising PANI-g-ND/gold particles was subsequently p...

Yudofsky, S.C.; Hales, R.E., 2002: Neuropsychiatry and the future of psychiatry and neurology. American Journal of Psychiatry 159(8): 1261-1264

Treffry T., 1978: Biogenesis of the photochemical apparatus. Bourne, G H And J F Danielli (Ed ) International Review Of Cytology, Vol 52 Vii+368p Illus Academic Press, Inc : New York, N Y , Usa; London, England Isbn 0-12-364352-X 159-196