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Noncanonical Wnt comes of age in hematopoietic stem cells

, : Noncanonical Wnt comes of age in hematopoietic stem cells. Cell Stem Cell 13(6): 642-643

Understanding molecular mechanisms of aging is crucial in efforts to reverse it. In a recent issue of Nature, Florian et al. (2013) report that increasing levels of noncanonical Wnt signaling accompany hematopoietic stem cell (HSC) aging, which can be modulated to functionally rejuvenate HSCs.


PMID: 24315437

DOI: 10.1016/j.stem.2013.11.009

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