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Novel layer-by-layer assembly molecularly imprinted sol-gel sensor for selective recognition of clindamycin based on Au electrode decorated by multi-wall carbon nanotube


, : Novel layer-by-layer assembly molecularly imprinted sol-gel sensor for selective recognition of clindamycin based on Au electrode decorated by multi-wall carbon nanotube. Journal of Colloid and Interface Science 344(1): 158-164

A novel sensitive molecularly imprinted electrochemical sensor was constructed for selective detection of clindamycin by combination of a multi-wall carbon nanotube (MWNT) layer with a thin molecularly imprinted sol-gel film. The sensor was fabricated onto Au electrode via stepwise modification of MWNT and a thin sol-gel film of molecularly imprinted polymers (MIP) by using electrodeposition method. The molecularly imprinted film displayed excellent selectivity towards clindamycin. Due to such combination, the sensor responded quickly to clindamycin. The response peak current was linear to the concentration of clindamycin in the range from 5.0 x 10(-7) mol L(-1) to 8.0 x 10(-5) mol L(-1), and the detection limit was 2.44 x 10(-8) mol L(-1). This imprinted sensor was applied to the determination of clindamycin in human urine samples successfully. These results revealed that the imprinted sensor fulfilled the selectivity, sensitivity, speed and simplicity requirements for clindamycin detection, and provided possibilities of clinical application in physiological fluids.

US$19.90

PMID: 20045524

DOI: 10.1016/j.jcis.2009.12.022


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Herishanu, Y.; Perry, C.; Braunstein, R.; Metser, U.; Goor, O.; Rogowski, O.; Berliner, S.; Polliack, A.; Naparstek, E., 2007: Early-mid treatment C-reactive protein level is a prognostic factor in aggressive non-Hodgkin's lymphoma. Background: In the light of an emerging role for early-mid treatment 18 F-deoxyfluoroglucose positron emission tomography (FDG-PET) as an important prognostic indicator in aggressive non-Hodgkin's lymphoma (NHL), we attempted to determine whe...

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Müntener, C.; Bruckner, L.; Stürer, A.; Althaus, F.; Caduff-Janosa, P., 2010: Vigilance for veterinary medicinal products: declarations of adverse reactions in the year 2008. With 106 reports of suspected adverse reactions to veterinary medicinal products (VMPs) there was a slight decrease in the year 2008 compared to 2007. However, the distribution according to species and drug classes remained grossly the same: dogs...

Sandford, F., 1987: Intra- and interspecific aggression in two species of field crickets, Gryllus integer and G. alogus. Adult, laboratory-reared, and singly caged field crickets, Gryllus integer, of known ages and representing F1 to F4 generations, were exposed to 15-20 minute bouts of social interaction with introduced adult intruder males on alternate days from a...

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