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Optimization of preload in severe sepsis and septic shock


, : Optimization of preload in severe sepsis and septic shock. Critical Care Research and Practice 2012: 761051-761051

In sepsis both under- and overresuscitation are associated with increased morbidity and mortality. Moreover, sepsis can be complicated by myocardial dysfunction, and only half of the critically ill patients exhibit preload responsiveness. It is of paramount importance to accurately, safely, and rapidly determine and optimize preload during resuscitation. Traditional methods of determining preload based on measurement of pressure in a heart chamber or volume of a heart chamber ("static" parameters) are inaccurate and should be abandoned in favor of determining preload responsiveness by using one of the "dynamic parameters" based on respiratory variation in the venous or arterial circulation or based on change in stroke volume in response to an endogenous or exogenous volume challenge. The recent development and validation of a number of noninvasive technologies now allow us to optimize preload in an accurate, safe, rapid and, cost-effective manner.

US$19.90

PMID: 22919473

DOI: 10.1155/2012/761051


Other references

Nashiki, M.; Nomoto, T.; Harashima, N., 1982: Seasonal productivity of herbage in pasture. II. The effect of the ratio of split applications on seasonal productivity of herbage. In newly established pasture late summer yield increased as the proportion of the N fertilizer applied in late summer increased, but weed populations also tended to increase. In the 2nd yr yields in late summer were increased if all N was applied...

Poluboyarinov, V.N.; Grabskii, Y.V.; Zemlyannikov, D.A.; Kushchev, G.G., 2016: Conditions of professional activity of the staff of units and formations of special support and its medical and psychological support. In the field of special support of nuclear- and radiation-dangerous objects "human factor" is highlighted, which means that psychological status of crew is at the first place. The authors analysed conditions of professional activity, det...

Bempong, D., K.; Honigberg, I., L.; Meltzer, N., M., 1993: Separation of 13-cis and all-trans retinoic acid and their photodegradation products using capillary zone electrophoresis and micellar electrokinetic chromatography (MEC). Two retinoic acid isomers; 13-cis retinoic acid and all-trans retinoic acid and their photodegradation products were resolved with capillary electrophoresis (CE) (UV detector, 345 nm) using three different mobile phases: method 1 - an acetonitrile...

Ashurmetov, A.A.; Dzevaltovs' kii, A.K. (Dzevaltovskij, A.K., 1978: Study of aspects of pollination and fruit formation in some melon varieties of Uzbekistan. In three cultivars each of Cucumis melo convars. chandalak, ameri and zard, and in subsp. agrestis, xenogamy, geitonogamy and autogamy occurred mainly with the help of insect pollinators. Natural autogamy did not occur in isolated hermaphrodite fl...

Yuan, S.H.; Sunahara, F.A.; Sen, A.K., 1987: Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart. Activation of protein kinase C has been implicated in the regulation of a variety of cellular reactions. Although we, and others, have found protein kinase C and its substrate proteins to be present in both membrane and cytosolic fractions in the...

Stone; Bingham; Riedinger; Lide; Carter; Mlekodaj; Spejewski, 1985: Decay of mass-separated 199Pom and 199Pog. Physical Review. C, Nuclear Physics 31(2): 582-592

Armstrong, M.T.; Turlo, K.; Elges, C.J.; Dayton, S.M.; Lee, J.; Armstrong, P.B., 2006: A novel form of epithelial wound healing of the embryonic epidermis. The embryonic epidermis of amniotes is a two-cell layer sheet with a periderm. positioned superficial to the basal cell layer which, itself, attaches apically to the basal surface of the periderm and basally to the basal lamina. The presence of th...

Taylor C.E.; Wong K.M., 1987: Some aspects of herbal medicine among the orang hulu community of kampung peta johore malaysia. Fifty-two plants species (belonging to 52 families) used for medicinal purposes by the Orang Hulu community of Kampung Peta in the Endau valley are documented. Their Orang Hulu names, uses, and methods of prescription are noted. Wherever applicabl...

Tablin, F.; Walker, N.J.; Klein, S.D.; Field, C.L.; Crowe, J.H., 2000: Animal models for studies on cold-induced platelet activation in human beings. When human platelets are chilled below about 20 degrees C, they spontaneously activate, a phenomenon that limits their storage lifetime. We have previously shown that this activation in chilled human platelets is associated with passage through a...

Sims; Martin, 1988: Variational calculations for 4He I: Improved energies for singlet and triplet n D and n F levels (n=3-8). Physical Review. A, General Physics 37(7): 2259-2269