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Outcome and predictive factors of successful transarterial embolization for the treatment of acute gastrointestinal hemorrhage

, : Outcome and predictive factors of successful transarterial embolization for the treatment of acute gastrointestinal hemorrhage. Acta Radiologica 55(2): 186-194

Transarterial embolization (TAE) is an effective procedure for the treatment of acute gastrointestinal bleeding (GIB). Factors associated with clinical success have not been well delineated. To evaluate the technical and clinical successes of TAE for acute GIB in order to identify factors influencing clinical success and in-hospital mortality. This was a retrospective study of 70 consecutive patients with GIB who underwent angiography and embolization between January 2004 and December 2011. The technical success rate, clinical success rate, and in-hospital mortality were calculated by percentage. Clinical parameters, angiographic, and embolization data were assessed for factors influencing clinical success and in-hospital survival using univariate and multivariate analysis. Statistical significance was set at P value <0.05. The technical success rate was 98.6%. The primary clinical success rate was 71.4% and the secondary clinical success rate after repeat embolization was 78.6%. Bowel infarction was the most serious complication of three (4.3%) patients. Failure to achieve 30-day hemostasis can be predicted in patients who have one or more of the following factors: hemoglobin concentration <8 g/dL (P = 0.004), coagulopathy (P = 0.005), upper GIB (P = 0.02), contrast extravasation (P = 0.012), and more than one embolized vessel (P = 0.005). In-hospital survival is affected by the amount of transfused packed red blood cells before embolization (P = 0.008) and post-embolization bowel infarction (P = 0.005). TAE is a feasible and effective management of acute GIB with high technical and clinical success rates. The factors influencing clinical success include hemoglobin concentration, coagulopathy, upper GIB, contrast extravasation, and more than one embolized vessel. The number of units of transfused packed red blood cells and post-embolization bowel infarction are important factors associated with in-hospital mortality.


PMID: 23904090

DOI: 10.1177/0284185113494985

Other references

Parichy, D.M.; Mellgren, E.M.; Rawls, J.F.; Lopes, S.S.; Kelsh, R.N.; Johnson, S.L., 2000: Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio. Pigment patterns of fishes are a tractable system for studying the genetic and cellular bases for postembryonic phenotypes. In the zebrafish Danio rerio, neural crest-derived pigment cells generate different pigment patterns during different phase...

Arendt, A.; Bachmann, P., 1966: Intracerebral vessel wall changes in hypertensive cerebral hemorrhage. Acta Neuropathologica 7(1): 79-85

Søderman, A.; Thomsen, M.S.; Hansen, H.H.; Nielsen, E.Ø.; Jensen, M.S.; West, M.J.; Mikkelsen, J.D., 2008: The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42. Recent studies have demonstrated that amyloid-beta1-42 (Abeta1-42) binds to the nicotinergic alpha7 acetylcholine receptor (alpha7 nAChR) and that the application of Abeta1-42 to cells inhibits the function of the alpha7 nAChR. The in vivo consequ...

Mukai H.; Ambe Y., 1987: Detection of monomethylarsenic compounds originating from pesticide in airborne particulate matter sampled in an agricultural area in japan. Alkylarsenic species in airborne particulate matter sampled in an agricultural area in Japan were investigated. The monomethyl form of arsenic, which has not been found so far in the air, was detected in a concentration as much as 1.4 ng m-3 in a...

Johnson, J.H., 1966: To the ramparts. Oral Health 56(8): 497-501

Linn, W.S.; Jones, M.P.; Bachmayer, E.A.; Clark, K.W.; Karuza, S.K.; Hackney, J.D., 1979: Effect of low-level exposure to ozone on arterial oxygenation in humans. We investigated the effect on arterial blood oxygenation of exposure to 0.2 ppm of ozone in purified air for 2 hours with intermittent light exercise and heat stress. Similar exposures to purified air alone provided control data. In 12 healthy vol...

Drets, M.E., 2004: Cytological indications of the complex subtelomeric structure. Research on the subtelomeric region has considerably increased because this chromosome segment (1) keeps the chromosome number constant, (2) intervenes in cancer and cell senescence processes, (3) presents more crossovers than other regions of the...

Werneck, F.L., 1944: O malofago do urso dos Andes. Mem Oswaldo Cruz, Rio de: 257-261

Kouyama, T., 1994: Supramolecular assembly of a membrane protein--hollow spheres of bacteriorhodopsin in its three-dimensional crystal. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme 39(3): 231-240

Hirano, K., 1985: Population dynamics of a phytophagous lady beetle henosepilachna vigintioctopunctata living in spatio temporally heterogenous habitats 1. estimation of adult population parameters based on a capture recapture census. 1. The population processes of the lady-beetle, Henosepilachna vigintioctopunctata (F.), were studied from the spring of 1976 to 1979 in an area (about 150,000 m2) including 17 patches of host plants. 2. Amplitudes of yearly fluctuations of adult...