geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Palladium-catalyzed C(sp2)-H cyanation using tertiary amine derived isocyanide as a cyano source


, : Palladium-catalyzed C(sp2)-H cyanation using tertiary amine derived isocyanide as a cyano source. Organic Letters 14(18): 4966-4969

An unprecedented palladium-catalyzed cyanation of aromatic C-H bonds by using tertiary amine derived isocyanide as a novel cyano source was developed. Cu(TFA)(2) was used as a requisite stoichiometric oxidant. Mechanistic studies suggest that a tertiary carbon cation-based intermediate is involved following the C-N bond breakage.

US$19.90

PMID: 22937807

DOI: 10.1021/ol302372p


Other references

Bonfils, S.; Baratgin, B.; Rossi, G.; Lambling, A., 1958: The mechanism of gastroduodenal complications induced by treatment with corticoids (cortisone and prednisone). Pathologie et Biologie 6(1-2): 133-139

Todd, J.E.; Whitworth, A., 1974: Adult dental health in Scotland 1972. British Dental Journal 137(4): 139-142

Cheng, Y-Kai.; Weng, H-Huei.; Yang, J-Tsung.; Lee, M-Hsueh.; Wang, T-Chung.; Chang, C-Nen., 2008: Factors affecting graft infection after cranioplasty. The aim of this study was to identify the risk factors associated with bone grafts infection after cranioplasty. Eighty-four cranioplasties were performed on 75 patients between 2002 and 2006. Cryopreserved bone grafts were used as graft material...

Willmore, E.; Elliott, S.L.; Mainou-Fowler, T.; Summerfield, G.P.; Jackson, G.H.; O'Neill, F.; Lowe, C.; Carter, A.; Harris, R.; Pettitt, A.R.; Cano-Soumillac, C.; Griffin, R.J.; Cowell, I.G.; Austin, C.A.; Durkacz, B.W., 2008: DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia. del(17p), del(11q), and associated p53 dysfunction predict for short survival and chemoresistance in B-cell chronic lymphocytic leukemia (CLL). DNA-dependent protein kinase (DNA-PK) is activated by DNA damage and mediates DNA double-strand break r...

Trento, H.; Oehling, A.; Ona, J., 1982: Effects of immunotherapy on histamine release: a study in allergy to dermatophagoides and house dust. Studies were carried out in Spain with 56 patients allergic to house dust and/or Dermatophagoides pteronyssinus (Trt.) and 50 healthy persons. The histamine-release test was carried out with antigens to both allergens, and the results were evaluat...

Giroux, J., 1988: Programme de reinsertion du merle-bleu a poitrine rouge. Carnets de Zoologie, 483: 58-66

Malhotra, D.; Wenk, R.E., 1992: Assessment of cyclosporine nephrotoxicity by H-1 magnetic resonance spectroscopy. Journal of the American Society of Nephrology 3(3): 727

Bogliolo, C.; Bacherini, A.M.; Puccetti, F., 1985: The psychiatric service and the family of a patient diagnosed psychotic. Minerva Psichiatrica 26(3): 237-241

Szilagyi, J.; Spanyar, P., 1975: Recent results of researches carried out in Hungary concerning the objective evaluation of the agricultural raw materials of the food industry. A detailed survey is given of the results obtained in various scientific and industrial research institutes and university departments concerning the objective evaluation of various products (must, wine, beer, molasses, wheat, rice, flour, hop ext...

Mauclaire L.; McKenzie J.A.; Schwyn B.; Bossart P., 2007: Detection and cultivation of indigenous microorganisms in Mesozoic claystone core samples from the Opalinus Clay Formation (Mont Terri rock laboratory). Although microorganisms have been isolated from various deep-subsurface environments, the persistence of microbial activity in claystones buried to great depths and on geological time scales has been poorly studied. The presence of in-situ microbi...