+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Partial vs. whole breast irradiation in a community hospital: a retrospective cohort analysis of 200 patients

, : Partial vs. whole breast irradiation in a community hospital: a retrospective cohort analysis of 200 patients. BrachyTherapy 9(3): 248-253

We compared patients undergoing partial breast irradiation (PBI) with the MammoSite applicator (Cytyc Corp., Marlborough, MA) to a similar group of patients who underwent whole breast irradiation with external beam radiotherapy. Stage 0-IIA breast cancer patients satisfying American Brachytherapy Society selection criteria and receiving accelerated PBI with the MammoSite system (n=100) were compared for toxicities with similarly staged patients receiving whole breast irradiation using tangential portals (n=100). The MammoSite applicator treatment was prescribed to a total dose of 34 Gy. External beam doses generally ranged from 60 to 66 Gy. Based on common toxicity criteria scores for acute toxicities, MammoSite patients experienced less cutaneous toxicity, fatigue, and breast pain and had higher Karnofsky performance status scores during the acute period than external beam patients but experienced more seroma pain during followup. These results were both statistically significant and clinically meaningful. In our institutional experience, PBI using the MammoSite applicator produces less acute toxicity than external beam radiotherapy of the whole breast but is associated with an increased incidence of seroma pain. The rate of disease recurrence in both cohorts was low.


PMID: 20153984

DOI: 10.1016/j.brachy.2009.12.002

Other references

Ludwicka, A., 1978: Preparation and evaluation of homogeneity of the t protein of streptococcus pyogenes type 12. A method was developed for isolation of T protein, consisting of digestion of the bacterial cells with insoluble trypsin linked to CNBr-sepharose. The preparation obtained was purified by ethanol precipitation and ion-exchange chromatography on th...

Sochivko, N.I.; Vorob' ev, V.F., 1978: Methodology of growing spring durum wheat under controlled light conditions. When 72 forms were grown in 12 h, 18 h or 24 h day for the first 20 days after emergence and in a 24 h day thereafter, grain yields were generally best with a 12 h day and worst with a 24 h day. Only one form gave a higher yield per m2 and a highe...

Ruasse, J.P., 1972: Advertisers' descriptions of special and diet foods. Special and diet foods were classed as follows. The "true-true" were those where a real quality such as low Na content was associated with a valid argument such as that the food was useful in a low-Na diet, e.g., salt-free mustard, oxala...

von E Doering, W.; Barsa, E.Albert., 2004: Fate of diradicals in the caldera: stereochemistry of thermal stereomutation and ring enlargement in cis- and trans-1-cyano-2(E)-propenylcyclopropanes. This study of thermally induced stereomutation and ring enlargement in both (-)-trans-1-cyano-2(E)-propenylcyclopropane [(-)-trans-1] and (+)-cis-1-cyano-2(E)-propenylcyclopropane [(+)-cis-1] to cyclopentenes definitively contraindicates the usefu...

Dobrogaeva, G.F.; Shchetinina, M.Z.; Neshta, K.P.; Chepurna, T.D., 1964: On The Problem Of Treating Chronic Pneumonia In Children. Pediatriia Akusherstvo i Ginekologiia 65: 6-9

Deuschl, G., 2008: Therapy of Parkinson's disease 2008. Mmw Fortschritte der Medizin 150 Suppl 2: 60-63

Lezdey, J.; Wachter, A., 1994: Method for deactivating viruses in blood component containers. Official Gazette of the United States Patent & Trademark Office Patents 1169(4): 2448, Dec 27

Frisk, P.Y.qob, A.N.lsson, K.L.ndh, U., 2001: Selenite or selenomethionine interaction with methylmercury on uptake and toxicity showing a weak selenite protection. Biological trace element research 80(3): 251-268

Holmes, C.B.; Thirumurthy, H.; Padian, N.S.; Goosby, E.P., 2010: AIDS funds: prevention. Science 330(6001): 176-7; Author Reply 177-8

Eversmeyer, M.; Browder, L.; Kramer, C., 1978: The effect of temperature on incubation period of Puccinia recondita f. sp. tritici. Phytopathology news 12 (9) 160