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Pathologic evaluation of explanted vaginal mesh: interdisciplinary experience from a referral center


, : Pathologic evaluation of explanted vaginal mesh: interdisciplinary experience from a referral center. Female Pelvic Medicine & Reconstructive Surgery 19(4): 238-241

In light of vaginal mesh safety concerns, we reviewed our institutional experience with analytic processes and pathologic findings of explanted vaginal mesh to identify problems and opportunities to facilitate improved documentation and research. We reviewed gross and microscopic pathology reports and archival slides of explanted mesh specimens from January 2010 through February 2012. Specimen requisition clinical history, number of mesh specimens per case, and type of examination (gross or histologic) were abstracted from pathology records using the initial search word "mesh". One hundred two cases were reviewed. Explanted mesh specimens included tissue in 97%. Forty-eight percent of these cases were submitted for histopathologic evaluation (as opposed to gross examination only). Specimen requisitions listed clinical history as pain (28.4%), vaginal mesh erosion (24.5%), erosion (17.6%), urinary retention (5.9%), and infection (2.9%). When no history was provided (24.5%), the case was more frequently submitted for histologic examination (74% vs 41%, P = 0.05). In all but 2 cases, the mesh material was polypropylene; no requisition mentioned this information. Gross descriptions of mesh varied significantly; in 18% of the cases, mesh was inaccurately described as "metallic". No cases of neoplasm were diagnosed histologically; all tissue diagnoses described benign reactive processes. Our experience suggests that either gross or histopathologic examination is appropriate for mesh explants. Documentation of clinical history, mesh product, and material was frequently incomplete and associated with increased submission of tissue for histologic examination and inaccurate gross impression of material type. We recommend improved documentation to aid pathologic examination and enable future pathophysiologic study of mesh complications.

US$19.90

PMID: 23797523

DOI: 10.1097/SPV.0b013e31829996e2


Other references

Conley, T.D.; Rabinowitz, J.L.; Hardin, C.D.; Simpson, O.J., 2010: O. J. Simpson as shared (and unshared) reality: the impact of consensually shared beliefs on interpersonal perceptions and task performance in different- and same-ethnicity dyads. Shared reality theory postulates that interpersonal relationships are regulated by the degree to which people share experiences and beliefs (Hardin & Higgins, 1996). To assess consequences of shared (and unshared) reality for interpersonal rel...

Bin Guangmei; Wang Chenyu; Chou Jingshao; Cun Chenqian, 1988: River regulation on the lower reaches of the Yellow River. Journal of Sediment Research 1988(4): 83-90

Vichev, Zh, 1977: Determining the width of the working chamber of a cotton harvester. The optimum limits of adjustment were determined theoretically and experimentally in relation to crop maturity, impurities, plant dimensions and the number of plants in clusters.

Flamant, Y.; Zantain, O.L.; Barge, J., 1992: Questionable appendectomies. Each year in France, 75,000 appendectomies are carried out for normal or fibrous appendix and another 75,000 for a mere inflammation of the mucosa of submucosa. To decrease the incidence--four times higher than in other countries--it is suggested...

Green, J.P.; Mohler, E.W., 2014: The death effect in literary evaluation: reverence for the dead?. It is commonly believed that the value of art and other creative works increases after the death of the artist. In an attempt to examine this so-called death effect we presented a short story to N = 431 undergraduate students asking how much money...

Grigorian, Gsh, 1974: Forming of meat qualities relative to the age of cattle. Zhivotnovudstvo 4 58-59

Carlberg, G.; Loras, V.M.ller, M.S.teland, N.T.eten, G., 1981: The bleaching of sulphite dissolving pulps. The effects of chip storage time and bleaching sequence on extractives of the pulp as well as on mutagenicity and on chlorinated organics in the effluents. Papier 35(7): 257-264

Freers, J.; Mayanja-Kizza, H.; Ziegler, J.L.; Rutakingirwa, M., 1996: Echocardiographic diagnosis of heart disease in Uganda. Five hundred consecutive cardiological patients were reviewed and evaluated by echocardiography in Mulago Hospital as a referral service. All diagnostic problems in cardiology in the hospital and to a certain degree from other institutions were re...

Kim, J.H.; Kim, Y.H.; Kim, M.R.; Kim, S-C., 2012: Clinical efficacy of different doses of rituximab in the treatment of pemphigus: a retrospective study of 27 patients. The treatment of pemphigus is still challenging and some pemphigus patients are unresponsive to conventional immunosuppressive treatments. Rituximab, a chimeric monoclonal anti-CD2 antibody, binds to the CD2 antigen on the surfaces of B cells and...

Ito, K.; Kawamura, S.; Horie, R.; Watanabe, T.; Mori, S., 1994: Expression of the CD-30 molecule in human decidual cells. Acta Histochemica et Cytochemica 27(4): 420