+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Penile haemodynamic changes in post-radical cystectomy patients

, : Penile haemodynamic changes in post-radical cystectomy patients. International Journal of Andrology 34(1): 27-32

The aim of this study was to assess the penile vascular changes in post-radical cystectomy patients. A prospective assessment took place between January 2003 and January 2005 of 45 potent men who underwent radical cystectomy and diversion for invasive bladder cancer. Nerve sparing (NS) technique was applied in 21 cases, while others were not subjected to NS (non-nerve sparing group; NNS = 24 cases). All patients were comparable in preoperative clinical and pathological parameters. A control arm was the preoperative normal indices of the same patients. Preoperative penile duplex ultrasounds (PDU) for all cases were carried out, and then follow-up 2, 6 and 12 months thereafter. On first postoperative visit, none of NS cases showed any arterial insufficiency, while two cases of NNS (8.3%) had peak systolic velocity (PSV) < 30 cm/sec. Moreover, all cases of both groups showed early increase of end diastolic velocity (EDV) > 5 cm/sec. In NS cystectomy group, the PSV showed statistically insignificant change [p > 0.05 (mean: 53.6, cm/sec)]. Shortly after surgery, the EDV values increased, followed by gradually significant improvement (decrease in EDV values) in comparison with control state (mean: 5.9 cm/sec). On the other hand, the NNS cases showed statistically insignificant changes in PSV (mean: 49.3 cm/sec), with deterioration in EDV that did not improve with time, in contrast to NS cases (mean: 13.15 cm/sec). The main significant penile vascular changes were in EDV (venogenic mechanism) in post-cystectomy patients. There was a gradual progressive improvement in venogenic competence mechanism in NS cases with insignificant deterioration of arteriogenic mechanism in both groups (NS/NNS).


PMID: 20158540

DOI: 10.1111/j.1365-2605.2009.01045.x

Other references

Awiszus, F., 2013: On relative frequency estimation of transcranial magnetic stimulation motor threshold. Clinical Neurophysiology 123(11): 2319-2320

Imperial, J.S.; Bansal, P.S.; Alewood, P.F.; Daly, N.L.; Craik, D.J.; Sporning, A.; Terlau, H.; López-Vera, E.; Bandyopadhyay, P.K.; Olivera, B.M., 2006: A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Using assay-directed fractionation of the venom from the vermivorous cone snail Conus planorbis, we isolated a new conotoxin, designated p114a, with potent activity at both nicotinic acetylcholine receptors and a voltage-gated potassium channel su...

Scott, P., 2007: Trace element deficiencies affecting adult sheep and their progeny. This paper discusses deficiencies in cobalt, copper, selenium and vitamin E, and iodine in sheep and their progeny.

Krol, A.; Unlu, M.Z.; Baum, K.G.; Mandel, J.A.; Lee, W.; Coman, I.L.; Lipson, E.D.; Feiglin, D.H., 2007: MRI/PET nonrigid breast-image registration using skin fiducial markers. We propose a finite-element method (FEM) deformable breast model that does not require elastic breast data for nonrigid PET/MRI breast image registration. The model is applicable only if the stress conditions in the imaged breast are virtually the...

Panté, N.; Aebi, U., 1995: Toward a molecular understanding of the structure and function of the nuclear pore complex. International Review of Cytology 162b: 225-255

Drechsel, D.; Hyman, A.A.; Hall, A.; Glotzer, M., 1996: The role of Rho and Cdc42 during cytokineses in cleaving xenopus embryos. Molecular Biology of the Cell 7(SUPPL ): 231A

Irwin, M.R., 1971: The evolution of 2 gene systems and of associated hybrid substances in columbidae. Genetics 68(4): 509-526

Kamdem, R.E.ery; Ho,, 2002: Diterpene lactone andrographolides An unusual class of nutritional antioxidant. Abstracts of Papers American Chemical Society 223(1-2): AGFD 12

Barker, R.A.; Currie, D.C.; Horwich, A.; Spiro, S.G., 1990: Metastatic non-seminomatous germ cell tumour and dermatomyositis. Twenty to thirty percent of cases of dermatomyositis in adults are associated with malignancy. We report a case in which dermatomyositis heralded the development of a testicular germ cell tumour. Germ cell testicular tumours are treatable and our...

Verma, S.K., 2006: Emerging insect pest problems of legumes in arid ecosystem. Changes in crop ecosystems in arid western Rajasthan, India, have brought changes in the insect pest problems in legumes. Polyphagous insects tend to prefer legumes. Seasonality and behaviour of scarab adults have changed. Aleyrodid Acaudaleyrodes...