+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Peritonitis: 10 years' experience in a single surgical unit

, : Peritonitis: 10 years' experience in a single surgical unit. Tropical Gastroenterology 28(3): 117-120

Peritonitis secondary to gut perforation is still one of the commonest surgical emergencies in India and is associated with high morbidity and mortality. The present study examines the aetiology and outcome of peritonitis cases operated on in our surgical unit, and compares our findings with those of previous studies performed between 1981 and 1991. A retrospective study of 260 peritonitis patients operated on in a single surgical unit from 1995 to 2006 was done and data involving clinical presentation, operative findings and post-operative course were studied and analysed. Causes of peritonitis were small bowel perforation (96 ileal, 17 jejunal), peptic perforation (45 duodenal, 16 gastric), appendicular perforation (36), primary peritonitis (8), and others (42). The incidence of major complications was 25% (burst-11%, leak-5%, intraabdominal abscess-5%, multi-organ failure-6.5%). The overall mortality was 10%. High mortality was observed in jejunal, gall bladder and liver abscess perforation cases (> 20%). Histopathological evaluation (143 specimens) revealed tuberculosis in 42 (mostly small bowel), malignancy in 8, and inflammation in the rest. Comparisons with a similar study carried out in the same unit and published in 1995 revealed similar demographic features and mortality, but a change in the most common cause (peptic ulcer perforation to small bowel perforation), and an increased performance of enterostomy compared with primary repair in small bowel perforation and a decrease in the leak rate (13% to 4%). Small bowel perforation is the commonest form of perforation and the mortality rate associated with peritonitis remains unchanged.


PMID: 18384000

Other references

Leonhardt, P., 1971: Perbronchial lymph node puncture. Zeitschrift für Erkrankungen der Atmungsorgane Mit Folia Bronchologica 135(1): 141-149

Rechnagel, K., 1960: Complications of the local use of hydrocortisone. Ugeskrift for Laeger 122: 111-113

Hrmo, V., 1975: Increasing organizational and managerial efficiency in developing co-operation and integration of agricultural production. The present stage of development of socialist agriculture in Czechoslovakia requires a systematic consolidation and improvement of the management system. Management is organized by functions, sectors and a combination of both. The functional struc...

Otomo, J.; Muramatsu, T., 1995: Over-expression of a new photo-active halorhodopsin in Halobacterium salinarium. The gene of haloopsin (hop) from halobacterial strain shark was cloned and its nucleotide sequence was determined. The deduced amino acid sequence of shark halorhodopsin (HR) showed that its homology with halobium HR was 62%. The gene product seem...

Fukuhara, M.; Tsurufuji, S., 1969: The effect of locally injected anti-inflammatory drugs on the synthesis of collagen and non-collagen protein of carrageenin granuloma in rats. Biochemical Pharmacology 18(10): 2409-2414

Jeserich, G.; Breer, H.; Düvel, M., 1981: Effect of exogenous gangliosides on synaptosomal membrane ATPase activity. Changes in the activity of (Na+, K+)-ATPase of synaptosomal membranes induced by exogenous gangliosides were studied. Depending on the ganglioside-protein ratio, the enzyme activity was finally reduced to 40% when the ratio was about 1. By analysi...

Li, J.; Liu, J.; Peng, H-Qing., 2008: Ethyl 4-nitro-phenyl-acetate. In the asymmetric unit of the title compound, C(10)H(11)NO(4), there are two crystallographically independent mol-ecules, which are connected via a C-H⋯O hydrogen bond. The crystal structure is stabilized by this hydrogen bond together with an N...

Garbutt, J.S.; Reynolds, S.E., 2012: Induction of RNA interference genes by double-stranded RNA; implications for susceptibility to RNA interference. Gene silencing by RNA interference (RNAi) can be a useful reverse genetics tool in eukaryotes. However, some species appear refractory to RNAi. To study the role of the differential expression of RNAi proteins in RNAi, we isolated partial dicer-2,...

Gregor Mikulas; Horvath Ivan; Mihalik Anton, 1970: The discovery of a new type kaolin in Czechoslovakia; its mineralogic and technological properties. Acta Universitatis Carolinae Geologica

Lu, Q.; Li, M.; Zou, Y.; Cao, T., 2015: Induction of adipocyte hyperplasia in subcutaneous fat depot alleviated type 2 diabetes symptoms in obese mice. The role of subcutaneous adipose tissue (SAT) in the pathogenesis of type 2 diabetes is still under controversy. In this study, the metabolic effects of inducing adipocyte hyperplasia in SAT depots in obese mice were investigated. High fat diet wa...