geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Post-operative pressure lability and cardiac baroreflex in normotensive patients as a function of age


, : Post-operative pressure lability and cardiac baroreflex in normotensive patients as a function of age. Acta Anaesthesiologica Scandinavica 52(9): 1250-1258

Pressure lability may be linked to the loss of the cardiac baroreflex. The reduction of the sensitivity of the cardiac baroreflex has not been delineated in the post-operative period according to age in normotensive patients. This study addresses pressure lability and slope of the cardiac baroreflex as a function of age. Patients were allocated to the following three groups: young (20-39 years, n=7), middle aged (40-59 years, n=7) and elderly (60-79 years, n=6), and studied before minor intra-abdominal surgery under CO(2) peritoneal insufflation and nitrous oxide-isoflurane-sufentanil anesthesia, up to 24 h after extubation. An electrocardiogram and non-invasive beat-by-beat pressure monitoring (Finapres) allowed offline calculation of the sensitivity of the cardiac baroreflex ('sequence' technique) and standard deviation (SD) of heart rate (HR; HR variability) and systolic blood pressure (SBP; pressure lability). Before anesthesia, (a) an inverse relationship was observed between the slope of the cardiac baroreflex and age and (b) a trend (P<0.09) existed between the slope of the cardiac baroreflex and pressure lability, irrespective of age. During the early post-operative period, young patients returned to their baseline slope of the cardiac baroreflex; no inverse relationship between increased SD of SBP and decreased SD of RR interval was observed. Middle-aged and elderly patients displayed a depressed slope of the cardiac baroreflex both before and after anesthesia. At variance with the pre-operative period, no simple inverse relationship was observed between increased pressure lability and depressed HR variability in young patients during the early post-operative period.

US$19.90

PMID: 18823465

DOI: 10.1111/j.1399-6576.2008.01740.x


Other references

Bullock, Rc, 1984: New developments in the biological control of insects on citrus. Citrus industry 65(8): 16-19

Donega, V.; Nijboer, C.H.; van Tilborg, G.; Dijkhuizen, R.M.; Kavelaars, A.; Heijnen, C.J., 2014: Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury. Previous work from our group has shown that intranasal MSC-treatment decreases lesion volume and improves motor and cognitive behavior after hypoxic-ischemic (HI) brain damage in neonatal mice. Our aim was to determine the kinetics of MSC migratio...

Monga, P.K.; Dhaliwal, U., 2009: Paradoxical reaction in tubercular meningitis resulting in involvement of optic radiation. A 25-year-old woman was diagnosed to have tubercular meningitis (TBM) with a right parietal infarct. She responded well to four-drug anti-tubercular treatment (ATT), systemic steroids and pyridoxine. Steroids were tapered off in one and a half mon...

Hibbard, B.M.; Basu, H.K., 1969: Laparoscopy in gynaecological practice. Journal of the Indian Medical Association 53(1): 1-6

Varentsov I.M.; Sokolova E.Y., 1995: Generation of synthetic magnetotelluric data. Physics of the Solid Earth 30(6): 554-562

Fujita, Y.; Hiyoshi, K.; Wakasugi, N.; Sakuta, R.; Yanagida, Y.; Fuchigami, T.; Gotoh, K.; Ohkubo, O.; Utsumi, Y., 1988: Transient improvement of the West syndrome in two cases following rotavirus colitis. No to Hattatsu. Brain and Development 20(1): 59-63

Amrhein, N., 1979: Growth. Recent work on the biochemistry and physiology of the gibberellins and cytokinins is reviewed with reference to methods of isolation and determination, occurrence, biosynthesis and metabolism and mechanism of action.

Ziatdinov, M.; Lim, H.; Fujii, S.; Kusakabe, K.; Kiguchi, M.; Enoki, T.; Kim, Y., 2017: Chemically induced topological zero mode at graphene armchair edges. The electronic and magnetic properties of chemically modified graphene armchair edges are studied using a combination of tight-binding calculations, first-principles modelling, and low temperature scanning tunneling microscopy (STM) experiments. T...

Digenis, G.A.; Khouri, C., 1999: Methods of treating eye conditions with human leukocyte elastase inhibitory agents. Official Gazette of the United States Patent & Trademark Office Patents 1224(2), Jul 13

Nasu, J.; Kato, Y.; Yoshitake, J.; Kamiya, Y.; Motome, Y., 2017: Spin-Liquid-to-Spin-Liquid Transition in Kitaev Magnets Driven by Fractionalization. While phase transitions between magnetic analogs of the three states of matter-a long-range ordered state, paramagnet, and spin liquid-are extensively studied, the possibility of "liquid-liquid" transitions, namely, between different spi...