geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Predictive factors analysis for malignant peritoneal mesothelioma


, : Predictive factors analysis for malignant peritoneal mesothelioma. Journal of Gastrointestinal Surgery 19(2): 319-326

Malignant peritoneal mesothelioma (MPM) is an uncommon disease with a dismal prognosis and unclear natural history. The present study aims to assess potential prognostic factors and management of MPM. Clinical records of 39 patients with MPM between December 2003 and April 2014 were retrospectively reviewed. Overall survival was identified with Kaplan-Meier curves and Cox regression analysis. Mean age of 39 patients was 55.0 years; asbestos exposure was recorded in two patients. Main presentations were abdominal distension, abdominal pain, and weight loss. Thrombocytosis, low serum albumin level, and anemia were principal laboratory abnormalities. Ascites, peritoneal cavity mass, and peritoneum thickening were the main signs on CT scans. Cytoreductive surgery (CRS) plus adjuvant therapies were performed in 22 patients, single chemotherapy in 13, and best supportive care in 4. Median survival time was 10.0 months after pathological diagnosis, with a 6-, 12-, 18-, and 24-month survival rate of 84.4, 31.6, 18.5, and 15.8 %, respectively. Significant prognostic factors were age, performance status (PS), abdominal pain, serum albumin level, thrombocytosis, and treatment strategy on univariate analysis, while only age, abdominal pain, and treatment strategy hold statistical significance on multivariate analysis. Age ≤65 years, abdominal pain, and CRS plus adjuvant therapy are independent positive prognostic factors of MPM.

US$19.90

PMID: 25297446

DOI: 10.1007/s11605-014-2664-4


Other references

Lu, B.R.; Salomon, B., 1993: Two new Tibetan species of Elymus (Poaceae: Triticeae) and their genomic relationships. E. cacuminus (2n = 4x = 28) and E. retroflexus (2n = 2x = 28), native to western China, are formally described and illustrated. To determine their genomic constitution they were crossed with Pseudoroegenia spicata [E. spicatus] (2n = 2x = 14, SS),...

Fischer J.A., 1972: Geological investigation for major offshore construction. Bulletin - New Jersey Academy of Science 17(2): 45

Muñoz, C.A.; Stephens, J.A.; Proskin, H.M.; Ghassemi, A., 2005: Clinical efficacy evaluation of calcium, phosphate, and sodium bicarbonate on surface-enamel smoothness and gloss. This clinical study evaluated the effectiveness of a fluoride dentifrice containing calcium, phosphate, and sodium bicarbonate for improving surface-enamel smoothness and gloss relative to a commercially available fluoride and silica-containing de...

Dobrochayeva, D.M.; Zaverukha, B.V., 1991: Botanical museum. Ukrayins'kyi Botanichnyi Zhurnal 48(6): 120-123

Vallilo, M.I.; Aguiar, O.T. de; Fiumarelli, J.; Martins Junior, H.A.; Sassine, A.; Bustillos, O.V., 2004: Identification of therpenes in the oil of the fruits of Campomanesia adamantium (Cambessedes) O Berg. Landrum - Myrtaceae. An experiment was conducted to analyse the volatile compounds present in Campomanesia adamantium, popularly known as guabiroba or gabiroba, by GC/MS technique. There were 34 compounds between monoterpenes C<sub>10</sub>H<sub>16&l...

Lopatkina I.V., 1987: Genesis of placers of endogenous origin. Izvestiya Vysshikh Uchebnykh Zavedeniy Geologiya i Razvedka

Baird J.R., 1986: Improving learning through enhanced metacognition a classroom study. A six-month classroom-based action-research study is reported, which involved 64 Grade 9 and 11 students, their teacher and the researcher. The study was directed to improving students' responsibility for, and control of, learning by training...

Ikezoe, T.; Kojima, S.; Furihata, M.; Yang, J.; Nishioka, C.; Takeuchi, A.; Isaka, M.; Koeffler, H.Phillip.; Yokoyama, A., 2011: Expression of p-JAK2 predicts clinical outcome and is a potential molecular target of acute myelogenous leukemia. Our study determined if Janus kinase 2 (JAK2) was activated in acute myelogenous leukemia (AML; n = 77, excluding acute promyelocytic leukemia) by immunohistochemistry (IHC) using a phosphor-specific antibody against JAK2. p-JAK2 was detectable in...

Bounias, M., 1986: Interactions agonistes et antagonistes de quelques effecteurs peptidergiques et aminergiques sur la lipemie de l'abeille in vivo. Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales, 1801: 89-97

Smith, E.M.; Treaster, S.A., 1990: Tolerance of clematis and wisteria to Ronstar and Devrinol. Oxadiazon (Ronstar) at 4 lb/acre and napropamide (Devrinol) at 4 and 8 lb gave good weed control in Clematis cv. Ernest Markham and Wisteria sinensis over a 10-week period in 1989, but caused slight damage to the Clematis.