+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Prevalence of hepatitis C virus genotypes in Mexican patients

, : Prevalence of hepatitis C virus genotypes in Mexican patients. Revista de Gastroenterologia de Mexico 72(4): 344-348

Worldwide HCV studies have documented its large genetic variability; HCV has major genetic groups called genotypes that are designated from 1 to 6, as well as > 50 subtypes. This is very important considering that treatment response varies according to genotype. The purpose of this trial was to ascertain prevalence of HCV genotypes in a group of patients from 10 states in Mexico. This study enrolled patients from 22 hospitals throughout the country. Patients tested positive to hepatitis C antibody and genotyping was preformed by Lipa method. To carry out a comparison, two regions were arbitrarily defined, the northern region embodied the cities of Culiacan, Torreón, Monterrey, Ciudad Obregón, and Tijuana, while the central-southern region embodied Mexico City, Guadalajara, León, Puebla, and Veracruz. The test was performed on a total of 421 patients. The most frequently found genotype was genotype 1, present in 70.55% of cases. The majority (40.1%) corresponded to genotype 1b, 17.81% to 1a, and genotype 2a/2c (11.64%). A total of 29.4% of samples corresponded to genotypes non-1. Genotype 1 was found in 72.34 (northern region) and 70.03% (central-southern) of the two regions, and genotypes non-1 in 27.66 and 29.97%, respectively. We conclude that the most frequent genotype in Mexico is 1b, followed by 1a, and, in third place 1b1a, for a total of 70.55%; the remaining 29.45% had genotypes other than 1.


PMID: 18595321

Other references

Rizzoli, R.; Ammann, P.; Bourrin, S.; Chevalley, T.; Bonjour, J.P., 2001: Protein intake and bone homeostasis. The roles over- and under intake of nutrition play in the pathogenesis of osteoporotic fracture and in bone development are discussed. The role of insulin-like growth factor in bone mass, muscle mass, risk of fracture and outcome after hip fractur...

Rosin, R.David., 2015: International Journal of Surgery. Editor's perspectives--June 2015. International Journal of Surgery 18: 245-246

Kesselheim, A.S.; Franklin, J.M.; Avorn, J.; Duke, J.D., 2014: Speaking the same language? International variations in the safety information accompanying top-selling prescription drugs. The official prescribing information document distributed with a prescription drug is a key source of safety information, but it may include excessive or insufficient details.To compare prescribing information approved by the US Food and Drug Admi...

de Waal, F.B.M.; Gavrilets, S., 2013: Monogamy with a purpose. Proceedings of the National Academy of Sciences of the United States of America 110(38): 15167-8

Ciannelli, L.; Brodeur, R.D.; Napp, J.M., 2004: Foraging impact on zooplankton by age-0 walleye pollock (Theragra chalcogramma) around a front in the southeast Bering Sea. The waters around the Pribilof Islands in the southeast Bering Sea are a center of abundance for age-0 walleye pollock (Theragra chalcogramma). Each spring and summer a tidal front is formed around the islands separating a well-mixed inshore habit...

Sargent, I.L.; Redman, C.W., 1985: Maternal cell-mediated immunity to the fetus in human pregnancy. Cell-mediated sensitisation of the mother to her fetus is not a regular event in human pregnancy, and the role of suppressor cells and blocking antibodies in preventing this sensitisation is unresolved. There is as yet little evidence to support t...

Iashan, I.; Kovalik, P.; Protasevich, G., 1987: Use of propolis therapy for chronic purulent mesotympanitis. Pchelovodstvo (5) 29

Mikulowski, P.; Kowalczykowa, J., 1971: In Memoriam: Prof. Dr.Med. Janina Kowalczykowa. Patologia Polska 22(2): 117-132

Muylle, E.; Oyaert, W., 1976: Auscultation of the equine heart. I. Normal heart sounds and their origin. In some normal horses five heart sounds can be heard. The atrial sound has a low frequency and a low amplitude. It is probably generated by the second rapid filling phase of the ventricles. The fourth heart sound is clearly separated from the firs...

Ando, D.; Nagata, M.; Kitamura, T.; Shinriki, Y., 2004: Evaluation of loss rate of coded-wire tags implanted into adipose eye tissue of masu salmon Oncorhynchus masou and effect on growth of tagged salmon. A total of ~30 000 tagged masu salmon smolts were stocked to investigate the tag loss rate and effect on growth for recovered adults. Insertion of coded-wire tags into adipose eye tissue of masu salmon had little or no effect on survival and growt...