geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Prognostic factors in critically ill patients with hematologic malignancies admitted to the intensive care unit


, : Prognostic factors in critically ill patients with hematologic malignancies admitted to the intensive care unit. Journal of Critical Care 27(6): 739.E1-6

Despite an improvement in the prognosis of patients with hematologic malignancies, the mortality of such patients transferred to the intensive care unit (ICU) is high. This study determined the predictors of mortality in a cohort of critically ill patients with hematologic malignancies admitted to the ICU. We studied 227 critically ill patients with hematologic malignancies who were admitted to the ICU between April 2009 and December 2011. A cohort of consecutive patients with hematologic malignancies was reviewed retrospectively to identify clinically useful prognostic factors. The ICU mortality rate was 84.1%, and the in-hospital mortality rate was 89.9%. The ICU mortality was significantly higher in patients with acute leukemia than in those with other malignancies. A significant difference between survivors and nonsurvivors was found in neutropenia and its recovery during the ICU stay, presence of cardiac dysfunction, the need for an invasive mechanical ventilator, use of inotropic/vasopressor agents, platelet count, aspartate transaminase level, pH, and Acute Physiology And Chronic Health Evaluation II score. In the multivariate analysis, acute leukemia, need for invasive mechanical ventilator, use of inotropic/vasopressor agents, and Acute Physiology And Chronic Health Evaluation II scores were independently associated with a worse outcome in patients with hematologic malignancies admitted to the ICU. Higher mortality in patients with hematologic malignancies admitted to the ICU is associated with more severe illness, as reflected by higher organ failure scores or respiratory or hemodynamic instability. Mortality is higher in patients with acute leukemia as compared with other hematologic malignancies.

US$19.90

PMID: 23217573

DOI: 10.1016/j.jcrc.2012.07.014


Other references

Peperstraete B.; Decoodt P.; Paternot J.; Dumont N.; Verhas M.; Telerman M., 1987: Predictors of the variation of the ejection fraction during exercise in patients with and without coronary heart disease. The aim of this study was to determine the factors influencing the different response to the ejection fraction (EF) of the left ventricle at exercise observed in patients with and without significant coronary heart disease. We have studied 98 pati...

L.C.unsheng, T.R.min; Gao Xiulan; L.A.min; Q.P.n, 1996: Plasma levels of endogenous opioid peptides and arginine vasopressin in patients with acute myocardial infarction. Chinese Medical Sciences Journal 11(3): 173

Potter, J.; Stott, D.J.; Roberts, M.A.; Elder, A.G.; O'Donnell, B.; Knight, P.V.; Carman, W.F., 1997: Influenza vaccination of health care workers in long-term-care hospitals reduces the mortality of elderly patients. Vaccination of health care workers (HCWs) is recommended as a strategy for preventing influenza in elderly patients in long-term care. However, there have been no controlled studies to show whether this approach is effective. During the winter of...

Leven J.; Tarlowski C.Z.; Scott D.L., 1997: Potential field modelling around the Murphy Inlier. Record - Australian Geological Survey Organisation 1997

Robert, Y.R.uze-Jouan, J., 1971: Transmission of potato leaf roll by greenfly. Pomme de terre francaise: 346 5-7

Zhang, Y.; Wang, Z-Yue.; He, X-Ping.; Liu, N.; Zhang, B-Run., 2008: New industrial brewing yeast strains with ILV2 disruption and LSD1 expression. New industrial brewing yeast strains, free of vector sequences and drug-resistance genes, were constructed by disrupting alpha-acetohydroxyacid synthase (AHAS) gene (ILV2) and introducing Lipomyces starkeyi dextranase (DEX) gene (LSD1) as a selec...

Murphy, P.A.; Hendrich, S.; Hopmans, E.C.; Lu, Z.; Buseman, G.; Munkvold, G., 1995: Effect of processing on the fumonisin content of corn. Abstracts of Papers American Chemical Society 209(1-2): AGFD 131

Bourjeily, G.; Khalil, H.; Miller, M.A.; O'Connor, K.; Rosene-Montella, K., 2008: Pregnancy and delivery in a patient with hypoplastic lung and dyspnoea. Journal of Obstetrics and Gynaecology 28(2): 228-229

Chiericato, G.M.; Rizzi, C.; Verdiglione, R., 2005: Effect of two dietary electrolyte balances on the zootechnical performance and on the biochemical profile of rabbit does. In this research the effect of the dietary electrolyte balance (dEB= Na++K+-Cl, meq/100 g) on the zootechnical performance and on the metabolic profile of 26 rabbit does, belonging to Grimaud genotype, at the third reproductive cycle was studied....

Kash, B.A.; Baek, J.; Davis, E.; Champagne-Langabeer, T.; Langabeer, J.R., 2017: Review of successful hospital readmission reduction strategies and the role of health information exchange. The United States has invested substantially in technologies that enable health information exchange (HIE), which in turn can be deployed to reduce avoidable hospital readmission rates in many communities. With avoidable hospital readmissions as t...