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Prognostic relevance of F-18 fluorodeoxyglucose positron emission tomography and computed tomography in molar pregnancy before evacuation


, : Prognostic relevance of F-18 fluorodeoxyglucose positron emission tomography and computed tomography in molar pregnancy before evacuation. Journal of Reproductive Medicine 54(7): 441-446

To assess prognostic significance of tumor metabolic activity of molar tissue by preevacuation F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) in patients clinically diagnosed with molar pregnancy. A total of 11 consecutive patients with clinical diagnosis of molar pregnancy before evacuation were enrolled. After evacuation of molar tissue, histopathologic findings and clinical follow-up were used as reference standards for the study. Six patients, 5 with complete and 1 with partial hydatidiform mole, had good outcome and normalization of beta-human chorionic gonadotropin (beta-hCG) levels within 5-7 weeks of evacuation. In the other 5 patients, serial measurements showed persistently and/or progressively elevated beta-hCG serum levels. These patients were treated with first-line single methotrexate or second-line etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine (EMA/CO) chemotherapy regimen. Standardized uptake value of molar tissue within the uterus in patients with persistently/progressively elevated beta-hCG levels was significantly higher than that in patients whose serum beta-hCG levels normalized after evacuation of molar tissue. Preliminary results suggest that F-18 FDG uptake within the uterus assessed by preevacuation PET/CT is predictive for probability of high-risk features of gestational trophoblastic disease or choriocarcinoma in patients with molar pregnancy.

US$29.90

PMID: 19691261


Other references

Pei, R.; Yang, X.; Wang, E., 2001: Enhanced surface plasmon resonance immunosensing using a streptavidin-biotinylated protein complex. In this paper, we present a novel strategy for improving the sensitivity of surface plasmon resonance immunosensing using a streptavidin-biotinylated protein complex. This amplification strategy is based on the construction of a molecular complex...

Holcroft, R.B., 1951: The Crowned Hawk-Eagle. A Diary of Observations. Africa Wild Life, 5: 107-109

Tsutsumi, K.; Tsuchiya, C.; Hanawa, K.; Suzuki, M.; Hanawa, T.; Oguchi, T., 2008: Evidence-based quality management of clinical formulations: determination of expiration date of powdered medicine prepared by grinding tablets. Beraprost sodium (BPS) is often used for pediatric patients with pulmonary hypertension. The purpose of this study was to determine the expiration date of the powdered medicine prepared by grinding tablets. In the present study, the hygroscopicity...

Nilius, A.M.; Beyer, J.M.; Flamm, R.K.; Tanaka, S.K., 1997: Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. The National Committee for Clinical Laboratory Standards (NCCLS) methods for susceptibility testing of Haemophilus influenzae in Haemophilus test medium allow a pH range of 7.2 to 7.4. However, it is known that bacteria may appear to be less susce...

Hardy, S.; McClay, K.; Munoz, J.A.ton, 2009: Deformation and fault activity in space and time in high-resolution numerical models of doubly vergent thrust wedges. A discrete-element model is used to investigate the manner in which deformation and fault activity change in space and time during the development of a doubly vergent thrust wedge in the upper crust. Deformation is a result of shortening at a subd...

Finsterer, J.; Mamoli, B., 1997: Satellite potentials as a measure of neuromuscular disorders. The study was carried out to investigate the characteristics of satellite potentials and their validity in clinical electromyography. Conventional needle electromyography was applied to the right biceps brachii and tibialis anterior muscles of 41...

Wu, X.; Liu, H., 2015: Obstructive sleep apnea/hypopnea syndrome increases glaucoma risk: evidence from a meta-analysis. Associations between Obstructive sleep apnea/hypopnea syndrome (OSAHS) and risk of glaucoma remained controversial. Therefore, we performed this meta-analysis to investigate this association. We searched Pubmed, EMBASE, and Wangfang databases for...

Zhang, Z.; Wang, Y.; Dong, M.; Cui, J.; Rong, D.; Dong, Q., 2012: Oxymatrine ameliorates L-arginine-induced acute pancreatitis in rats. The aim of this study was to determine whether oxymatrine has a protective effect against acute pancreatitis (AP) in a rat model of l</small>-arginine-induced AP. AP was induced by two intraperitoneal injections of l</small>-arginine (...

Kazheva, O.N.; Alexandrov, G.G.; Kravchenko, A.V.; Kosenko, I.D.; Lobanova, I.A.; Sivaev, I.B.; Filippov, O.A.; Shubina, E.S.; Bregadze, V.I.; Starodub, V.A.; Titov, L.V.; Buravov, L.I.; Dyachenko, O.A., 2010: Molecular conductors with a 8-hydroxy cobalt bis(dicarbollide) anion. Molecular conductors based on the 8-hydroxy cobalt bis(dicarbollide) anion, (TMTTF)[8-HO-3,3'-Co(1,2-C2B9H10)(1',2'-C2B9H11)] (1), (BMDT-TTF)[8-HO-3,3'-Co(1,2-C2B9H10) (1',2'-C2B9H11)] (2), and (BEDT-TTF)[8-HO-3,3&apo...

Tan Ming; Liu Tungsheng, 1996: Monsoon data from oxygen isotope of speleothems in East China; an example from Beijing Shihua Cave. Karst Waters Institute Special Publication: ges 163-164. 1996.