+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

QT restitution properties of middle-aged women with different exercise capacities

, : QT restitution properties of middle-aged women with different exercise capacities. Journal of Electrocardiology 44(3): 340-345

Framingham Study data indicate an incremental risk of cardiovascular death in relation to low exercise capacity in women. The reason for death is still not clear. QT restitution properties in 80 middle-aged women were investigated to confirm whether the cardiac restitution property was affected by the exercise capacity. Exercise tests were performed according to the Bruce protocol. Seventy cases were divided into the low-exercise capacity group (LEC group) and high-exercise capacity group (HEC group) by median exercise capacities. Sequential QT intervals and their preceding TQ intervals were measured, and the QT restitution curve (QTRC) was constructed. Two exponential equations were used to match the data and calculate the maximum slope (Smax) of QTRC, respectively. With elevation in the exercise level, the women in the LEC group had a higher change rate of QT intervals (41 ± 10 vs 29 ± 3 ms/Met, P = .001) and TQ intervals (46 ± 12 vs 41 ± 7 ms/Met, P = .046); and the ratio of QT interval alterations to TQ interval alterations increased (0.41 ± 0.09 vs 0.36 ± 0.07, P = .003). The Smax of the QTRC in the LEC group was higher than that in the HEC group (1.43 ± 0.44 vs 1.13 ± 0.34, P = .002). There was an inverse relationship between Smax and exercise capacity (r = -0.43, P = .001). Middle-aged women with low exercise capacity have steeper QTRCs than those with high exercise capacity, denoting a more unstable alternation of QT interval with elevation in exercise level.


PMID: 20719335

DOI: 10.1016/j.jelectrocard.2010.06.014

Other references

Volpe, C.M.; Mehta, N.; Kim, U.; Hordines, J.; Doerr, R.J.; Cohen, S.A., 1999: AsGM1+ NK cells prevent metastasis of invading LD-MCA-38 tumor cells in the nude mouse. Background. Although the liver is a potent tumor cell killing organ it is frequently the site of lethal metastases often signifying the endstage for patients with colorectal cancers. Enhancing hepatic-associated immunity remains elusive until the...

Pfeffer, P., 1960: Etude d'une collection d'oiseaux de Borneo (a suivre). Oiseau, 30: 191-218

Vral, A.; Thierens, H.; Baeyens, A.; D.R.dder, L., 2002: The micronucleus and G2-phase assays for human blood lymphocytes as biomarkers of individual sensitivity to ionizing radiation: limitations imposed by intraindividual variability. As a part of a program to assess the applicability of the micronucleus (MN) and G2-phase assays as biomarkers of cancer susceptibility, we investigated the inter- and intraindividual variations of these end points. For the MN assay, unstimulated b...

Sharma, P.K.; Bhardwaj, R.; Dwarakanath, B.S.; Varshney, R., 2010: Metabolic oxidative stress induced by a combination of 2-DG and 6-AN enhances radiation damage selectively in malignant cells via non-coordinated expression of antioxidant enzymes. Our earlier studies have shown that simultaneous inhibition of glycolysis and pentose phosphate pathway using 2-deoxy-d-glucose (2-DG, an inhibitor of glycolysis) and 6-aminonicotinamide (6-AN, an inhibitor of pentose phosphate pathway) lead to me...

Sakhelashvilli, LZ.; Kvantaliani, IV., 1990: On first find of Abrytusites neumayri Ammonoidea in the Lower Cretaceous deposits of the south of the USSR. Soobshcheniya Akademii Nauk Gruzinskoi SSR: 1392: 345-348

Pourquié, O.; Brown, K., 2016: Introducing cross-referee commenting in peer review. Development 143(17): 3035-3036

Gunthart, E.; Holenstein, R., 1947: Life cycle and control of the plum sawfly. The life cycles of Hoplocampa minuta and H. flava (the black and the yellow plum sawflies) are similar in Switzerland. Benzene hexachloride (1%) applied immediately after flowering gave better control than the DDT products tested.

Cuezzo, Fabiana, 1999: New records of ants Tribes Dacetini and Basicerotini to the Argentine Republic. Revista de la Sociedad Entomologica Argentina 58(3-4): 209-210

Choi, M.Y.on; Jurenka, R.A., 2006: C75, a fatty acid synthase inhibitor, inhibits feeding activity and pheromone production in a moth, Helicoverpa zea. Fatty acid synthesis produces long-chain fatty acids that are principal forms of stored energy and essential constituents of cellular membrane Lipids. In animals fatty acid synthesis is catalyzed by fatty acid synthase (FAS) from acetyl-coenyzyme...

Singh, S.; Mehrotra, A., 1999: Histopathological changes induced by carbaryl in the intestine of fresh water fish Nandus nandus. Journal of Ecotoxicology and Environmental Monitoring. April; 92: 129-132