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Recreational physical activity and risk of Parkinson's disease


, : Recreational physical activity and risk of Parkinson's disease. Movement Disorders 23(1): 69-74

The purpose of this study was to investigate associations between recreational physical activity and Parkinson's disease (PD) risk. We prospectively followed 143,325 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2001 (mean age at baseline = 63). Recreational physical activity was estimated at baseline from the reported number of hours per week on average spent performing light intensity activities (walking, dancing) and moderate to vigorous intensity activities (jogging/running, lap swimming, tennis/racquetball, bicycling/stationary bike, aerobics/calisthenics). Incident cases of PD (n = 413) were confirmed by treating physicians and medical record review. Relative risks (RR) were estimated using proportional hazards models, adjusting for age, gender, smoking, and other risk factors. Risk of PD declined in the highest categories of baseline recreational activity. The RR comparing the highest category of total recreational activity (men > or = 23 metabolic equivalent task-hours/week [MET-h/wk], women > or = 18.5 MET-h/wk) to no activity was 0.8 (95% CI: 0.6, 1.2; P trend = 0.07). When light activity and moderate to vigorous activity were examined separately, only the latter was found to be associated with PD risk. The RR comparing the highest category of moderate to vigorous activity (men > or = 16 MET-h/wk, women > or = 11.5 MET-h/wk) to the lowest (0 MET-h/wk) was 0.6 (95% CI: 0.4, 1.0; P trend = 0.02). These results did not differ significantly by gender. The results were similar when we excluded cases with symptom onset in the first 4 years of follow-up. Our results may be explained either by a reduction in PD risk through moderate to vigorous activity, or by decreased baseline recreational activity due to preclinical PD.

US$19.90

PMID: 17960818

DOI: 10.1002/mds.21772


Other references

Biagioli, M., 1998: The instability of authorship: credit and responsibility in contemporary biomedicine. Faseb Journal 12(1): 3-16

Konecki, D.; Cimadevilla, J.M.; Kramer, G.; Hardesty, B., 1975: A simple method for the purification of reticulocyte globin messenger ribonucleic acid. A relatively simple and inexpensive method has been developed for the preparation of highly purified rabbit reticulocyte globin mRNA. After phenol extraction, polysomal RNA was chromatographed on Sigmacell type 38 cellulose and Sepharose 4B. The r...

Ding, N.; Simon, J.Z., 2013: Power and phase properties of oscillatory neural responses in the presence of background activity. Natural sensory inputs, such as speech and music, are often rhythmic. Recent studies have consistently demonstrated that these rhythmic stimuli cause the phase of oscillatory, i.e. rhythmic, neural activity, recorded as local field potential (LFP)...

Kennedy, G.T., 1977: Some social and economic aspects of farm syndication. The aim was to examine the effects of complete integration of farms in farm syndicates by a study of four production syndicates in the Wimmera region of Victoria, Australia ranging in size from two to eight farmer members. The syndicates were asse...

Hume, D.E., 1991: Effect of cutting on production and tillering in prairie grass bromus willdenowii kunth compared with two ryegrass lolium spp 1. vegetative plants. Effects of cutting to 3 or 6 cm stubble height at frequencies of 1, 2, or 4 weeks were investigated in young, vegetative, spaced plants of prairie grass (Bromus willednowii Kunth), a tetraploid Westerwolds ryegrass (Lolium multiflorum Lam.) and pe...

Tiwari P.N.; Gambhir P.N.; Nath K.K.; Chahal S.S., 1986: Application of nmr in study of drought tolerance of cereal crops. Spin-lattice relaxation time T1 of water in leaf of pearl-millet, barley, wheat and rice, which are known to differ in their drought tolerance, has been measured by pulsed NMR at 20 MHz and ambient temperature. T1 of each crop has two components....

Patel J.M.; Block E.R., 1983: Cyclo phosphamide potentiates oxygen toxicity by depressing lung anti oxidant defense. American Review of Respiratory Disease 127(4 PART 2): 284

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McGinn, T.G., 2013: On being a physician…when you wish you weren't. Journal of General Internal Medicine 28(2): 328-329

Sharma, A.P.; Singh, S.P., 1994: Genotypic variation in photosynthesis and yield component in rice. Genotypic differences in photosynthetic rate (42.8 to 29.3 mg CO-2 dm-2h-1) were observed among 22 rice cultivars in advanced yield trial. Genotypes, AYTI2448, AYTI2364, AYTI2343 and AYTI2488 recorded high rate of photosynthesis (40 mg CO-2 dm-2h-...