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Relationships between repeated instruction on inhalation therapy, medication adherence, and health status in chronic obstructive pulmonary disease


, : Relationships between repeated instruction on inhalation therapy, medication adherence, and health status in chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 6(): 97-104

Adherence to inhalation therapy is a critical determinant of the success of chronic obstructive pulmonary disease (COPD) management. However, in practice, nonadherence to inhalation therapy is very common in COPD patients. The effects of adherence to inhalation therapy in COPD have not been fully studied, and less is known about the relationship between medication adherence and quality of life in COPD. Our aim is to assess the factors that contribute to adherence to inhalation therapy and examine their correlation with quality of life. A cross-sectional analysis of 88 COPD patients was performed using a self-reported adherence questionnaire with responses on a 5-point Likert scale. Of the 88 patients who were potential participants, 55 (63%) responded with usable information. The only significant factor associated with the overall mean adherence score was receiving repeated instruction about inhalation techniques (P = 0.032). Of the 55 respondents, 22 (40.0%) were given repeated verbal instruction and/or demonstrations of inhalation technique by a respiratory physician. Significant correlations were found between the overall mean adherence score and the health-related quality of life score (St George's Respiratory Questionnaire: total, r = -0.35, P = 0.023; symptoms, r = -0.43, P = 0.002; impacts, r = -0.35, P = 0.011). Furthermore, patients with repeated instruction showed better quality of life scores than those who did not receive instruction (total, P = 0.030; symptoms, P = 0.038; impacts, P = 0.019). Repeated instruction for inhalation techniques may contribute to adherence to therapeutic regimens, which relates to better health status in COPD.

US$19.90

PMID: 21407822

DOI: 10.2147/COPD.S16173


Other references

Bradley, J.D.; Paulus, R.; Graham, M.V.; Ettinger, D.S.; Johnstone, D.W.; Pilepich, M.V.; Machtay, M.; Komaki, R.; Atkins, J.; Curran, W.J., 2005: Phase II trial of postoperative adjuvant paclitaxel/carboplatin and thoracic radiotherapy in resected stage II and IIIA non-small-cell lung cancer: promising long-term results of the Radiation Therapy Oncology Group--RTOG 9705. To determine the overall survival, progression-free survival, and toxicity associated with concurrent paclitaxel/carboplatin and thoracic radiotherapy for completely resected patients with stage II and IIIA non-small-cell lung cancer (NSCLC). Eigh...

Shires, T.K., 1982: Iron-induced DNA damage and synthesis in isolated rat liver nuclei. Incubation of iron with isolated rat liver nuclei stimulated fragmentation of single-stranded DNA, incorporation of [3H]thymidine into DNA and the binding of 59Fe to DNA. FeCl2 was about twice as active as FeCl3. Lipid peroxidation took place in n...

Anonymous, 1982: Nuclear Safety Program; 1981 annual report. Kernforschungszentrum Karlsruhe 3250(1982

Russell, B.J.; Miller, B., 2000: Comparison of mold spores in 1998 and 1999. Journal of Allergy & Clinical Immunology 105(1 part 2): S336, Jan

Mitomi, T.; Kyoji-Ogoshi, 1986: Clinical study of PSK as an adjuvant immunochemotherapeutic agent against gastric cancer. The effects of PSK in combination with Mitomycin C, Adriamycin and Tegafur were studied in 168 patients who underwent gastrectomy for gastric cancer. The study group receiving PSK showed improved survival and there was a significant difference in...

Holland, J.M., 1994: A MAFF link project - integrated farming systems. A project to investigate the economic, agronomic and environmental effects of a conventional and an integrated farming system was initiated in the UK in 1992. At each of 6 sites, a minimum of 5 fields will be used to cover a 5-course rotation. Eac...

Jones R.N.; Erwin M.E.; Barrett M.S., 1991: Proposed interpretive criteria for susceptibility tests with 5 micrograms ci 960 pd 127391 disks. Program & Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 31: 290

Zharinov, O.I.; Sallam, S.; Komorovs'kyĭ, R.R.; Oryshchyn, N.D., 2003: Diastolic filling of the right ventricle in patients with arterial hypertension and ischemic heart disease. Our objective in this study was to compare particular features of pathogenesis of diastolic dysfunction of the right ventricle (RV) in patients with arterial hypertension (AH), stable exertional angina, and myocardial infarction of the left ventri...

Fioravanti, M.; Ferrario, E.; Massaia, M.; Cappa, G.; Rivolta, G.; Grossi, E.; Buckley, A.E., 2008: Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits. The relevance of low folate levels as determinants of cognitive deficits and the usefulness of folate supplementation in the treatment of cognitive deficits was reviewed from the literature. Over 40 papers and book chapters published in English, F...

Budyanskii, V.M.; Gorelov, V.G.; Shulutko, E.M.; Mikhailova, E.A.; Mosolova, S.V., 1996: Spontaneous gas gangrene in a female with aplastic anemia. Terapevticheskii Arkhiv 68(2): 70-71